UniprotIds |
Genes |
Protein Names |
New Plasma SASP Protein |
Q13740 |
ALCAM |
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166) |
YES |
P21810 |
BGN |
Biglycan (Bone/cartilage proteoglycan I) (PG-S1) |
YES |
Q14019 |
COTL1 |
Coactosin-like protein |
YES |
P01034 |
CST3 |
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin) |
YES |
P07858 |
CTSB |
Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] |
NO |
P07339 |
CTSD |
Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain] |
YES |
Q9UBR2 |
CTSZ |
Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) |
YES |
P02751 |
FN1 |
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3] |
YES |
Q99988 |
GDF15 |
Growth/differentiation factor 15 (GDF-15) (Macrophage inhibitory cytokine 1) (MIC-1) (NSAID-activated gene 1 protein) (NAG-1) (NSAID-regulated gene 1 protein) (NRG-1) (Placental TGF-beta) (Placental bone morphogenetic protein) (Prostate differentiation factor) |
YES |
P06396 |
GSN |
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin) |
YES |
P09211 |
GSTP1 |
Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1) |
YES |
P0DMV8 |
HSPA1A |
Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 1) (HSP70-1) (HSP70.1) |
YES |
P11142 |
HSPA8 |
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) |
YES |
P18065 |
IGFBP2 |
Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2) |
NO |
Q16270 |
IGFBP7 |
Insulin-like growth factor-binding protein 7 (IBP-7) (IGF-binding protein 7) (IGFBP-7) (IGFBP-rP1) (MAC25 protein) (PGI2-stimulating factor) (Prostacyclin-stimulating factor) (Tumor-derived adhesion factor) (TAF) |
NO |
P03956 |
MMP1 |
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase] |
YES |
P08253 |
MMP2 |
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX] |
YES |
Q99497 |
PARK7 |
Protein/nucleic acid deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase) (Oncogene DJ1) (Parkinson disease protein 7) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) |
YES |
P00558 |
PGK1 |
Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) |
YES |
Q15063 |
POSTN |
Periostin (PN) (Osteoblast-specific factor 2) (OSF-2) |
YES |
P05155 |
SERPING1 |
Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1) |
YES |
P52823 |
STC1 |
Stanniocalcin-1 (STC-1) |
YES |
P01033 |
TIMP1 |
Metalloproteinase inhibitor 1 (Erythroid-potentiating activity) (EPA) (Fibroblast collagenase inhibitor) (Collagenase inhibitor) (Tissue inhibitor of metalloproteinases 1) (TIMP-1) |
NO |
P16035 |
TIMP2 |
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) |
NO |
P27348 |
YWHAQ |
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1) |
YES |
Reference: A proteomic atlas of senescence-associated secretomes for aging biomarker development Nathan Basisty,et al, PLOS Biology, 2020 |