Name |
Symbol |
Entrez ID |
Max average lifespan change |
Acyl-CoA-Binding |
ACB1 |
852925 |
Upregulated |
Adenine AminoHydrolase |
AAH1 |
855581 |
Upregulated |
Adenine PhosphoribosylTransferase |
APT1 |
854986 |
Upregulated |
Adenine requiring |
ADE1 |
851272 |
Upregulated |
Adenine requiring |
ADE12 |
855501 |
Upregulated |
Adenine requiring |
ADE2 |
854295 |
Upregulated |
Adenine requiring |
ADE4 |
855346 |
Upregulated |
Adenine requiring |
ADE5,7 |
852617 |
Upregulated |
Adenine requiring |
ADE6 |
852952 |
Upregulated |
Adenylate cyclase |
CYR1 |
853452 |
90% Upregulated |
Adenylyl-sulfate kinase |
MET14 |
853869 |
Upregulated |
ADP/ATP Carrier |
AAC3 |
852380 |
15% Upregulated |
Alcohol DeHydrogenase |
ADH1 |
854068 |
20% Upregulated |
ALdehyde Dehydrogenase |
ALD4 |
854556 |
50% Upregulated |
Aldehyde dehydrogenase (NADP(+)) ALD6 |
ALD6 |
856044 |
Upregulated |
Alpha-1,2-mannosyltransferase MNN2 |
MNN2 |
852303 |
16% Upregulated |
Alpha-1,3-mannosyltransferase MNN1 |
MNN1 |
856718 |
15% Upregulated |
AMP Deaminase |
AMD1 |
854973 |
Upregulated |
Arginine permease CAN1 |
CAN1 |
856646 |
30% Upregulated |
Ark family Kinase-Like protein |
AKL1 |
852351 |
20% Upregulated |
Aromatic amino acid transmembrane transporter TAT2 |
TAT2 |
854139 |
23% Upregulated |
Asparagine-Linked Glycosylation |
ALG12 |
855764 |
25% Upregulated |
Asparagine-Linked Glycosylation |
ALG5 |
855874 |
50% Upregulated |
Aspartate-Glutamate Carrier |
AGC1 |
856132 |
30% Upregulated |
ATP synthase |
ATP3 |
852327 |
50% Upregulated |
ATPase Family Gene |
AFG3 |
856737 |
20% Upregulated |
BASal |
BAS1 |
853974 |
30% Upregulated |
Bem1 (One) Interacting protein |
BOI2 |
856850 |
25% Upregulated |
Bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17 |
MET17 |
851010 |
100% Upregulated |
Bile Pigment Transporter |
BPT1 |
850645 |
20% Upregulated |
Biosynthesis of Nicotinic Acid |
BNA2 |
853541 |
Upregulated |
Bst1p |
BST1 |
850519 |
25% Upregulated |
Bypass of Stop Codon |
BSC2 |
851868 |
20% Upregulated |
Bypass of Stop Codon |
BSC1 |
851524 |
20% Upregulated |
CaRnitine Carrier |
CRC1 |
854267 |
25% Upregulated |
Casein Kinase Alpha' subunit |
CKA2 |
854227 |
Upregulated |
CaTalase A |
CTA1 |
851843 |
Upregulated and Downregulated |
Cbp6p |
CBP6 |
852417 |
25% Upregulated |
Cbs1p |
CBS1 |
851491 |
37% Upregulated |
Cdc25p |
CDC25 |
851019 |
50% Upregulated |
Cell division cycle |
CDC6 |
853244 |
20% Upregulated |
Ceramide synthase component |
LAG1 |
856386 |
50% Upregulated |
Chromosome STability |
CST26 |
852330 |
40% Upregulated |
Cln3p |
CLN3 |
851191 |
Downregulated |
Csr2p |
CSR2 |
856142 |
Upregulated |
CYStathionine beta-synthase |
CYS4 |
853059 |
50% Upregulated |
Cysteine-Three-Histidine |
CTH1 |
851729 |
20% Upregulated |
Cytoplasmic pre-60S factor |
REI1 |
852569 |
40% Upregulated |
Dead Box Protein |
DBP3 |
852802 |
35% Upregulated |
Defective Cell Wall |
DCW1 |
853820 |
Upregulated |
Deficient in Utilization of Glutathione |
DUG1 |
850605 |
Upregulated |
Der1p |
DER1 |
852500 |
16% Upregulated |
Derepression of ITR1 Expression |
DIE2 |
853142 |
50% Upregulated |
Dls1p |
DLS1 |
853381 |
20% Upregulated |
Dnm1p |
DNM1 |
850686 |
Upregulated |
dolichyl-diphosphooligosaccharide--protein glycotransferase OST3 |
OST3 |
854252 |
20% Upregulated |
dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase |
ALG6 |
854163 |
15% Upregulated |
dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase |
ALG3 |
852196 |
10% Upregulated |
Drs2 Neo1 Family |
DNF1 |
856913 |
50% Upregulated |
Dst1-delta 6-Azauracil Sensitivity |
DAS2 |
851583 |
25% Upregulated |
ELongator Protein |
ELP3 |
856019 |
Upregulated |
ELongator Protein |
ELP4 |
856002 |
30% Upregulated |
Eos1p |
EOS1 |
855644 |
24% Upregulated |
ER oxidoreductin |
ERO1 |
854909 |
28% Upregulated |
Essential for Respiration and Viability |
ERV2 |
856152 |
Upregulated |
Factor ARrest |
FAR10 |
850939 |
Upregulated |
Factor ARrest |
FAR8 |
855044 |
Upregulated |
Ferric REductase 6 |
FRE6 |
850675 |
14% Upregulated |
Five Zinc Fingers |
FZF1 |
852638 |
66% Upregulated |
FluoroCYtosine resistance |
FCY2 |
856783 |
Upregulated |
FluoroCYtosine resistance |
FCY21 |
856788 |
Upregulated |
FluoroCYtosine resistance |
FCY1 |
856175 |
Upregulated |
Fob1p |
FOB1 |
851688 |
50% Upregulated |
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for gluc |
FBP1 |
851092 |
Downregulated |
GDP/GTP exchange protein (GEP) for Rho1p and Rho2p |
ROM2 |
851086 |
50% Upregulated |
GIg1-2 Suppressor |
GIS1 |
851670 |
25% Upregulated |
gluconokinase |
YDR248C |
851835 |
20% Upregulated |
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2 |
TDH2 |
853465 |
29% Upregulated |
Gpr1p |
GPR1 |
851527 |
50% Upregulated |
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway |
RAS1 |
854268 |
23% Upregulated |
Hes1p |
HES1 |
854412 |
25% Downregulated |
hexokinase 2 |
HXK2 |
852639 |
50% Upregulated |
high-Affinity Glutamine Permease |
AGP1 |
850333 |
Upregulated |
Histone deacetylase |
RPD3 |
855386 |
41% Upregulated |
Histone DeAcetylase |
HDA1 |
855710 |
Upregulated |
HnRNP MethylTransferase |
HMT1 |
852322 |
50% Upregulated |
homolog of S. pombe SDS23 |
SDS23 |
852824 |
Upregulated |
Homologous to RAD4 |
RAD34 |
851909 |
30% Upregulated |
Hsp70 family ATPase SSC1 |
SSC1 |
853503 |
40% Upregulated |
Hyper-resistance to Nitrogen Mustard |
HNM1 |
852803 |
Upregulated |
hypothetical protein |
YBR238C |
852540 |
30% Upregulated |
hypothetical protein |
YLR422W |
851141 |
25% Upregulated |
hypothetical protein |
YMR018W |
855032 |
35% Upregulated |
hypothetical protein |
YGR130C |
853031 |
30% Upregulated |
hypothetical protein |
YOR012W |
854177 |
Upregulated |
hypothetical protein |
YER186C |
856935 |
30% Upregulated |
hypothetical protein |
YER187W |
856937 |
30% Upregulated |
hypothetical protein |
YMR010W |
855022 |
30% Upregulated |
Hypothetical RNA-Binding protein |
HRB1 |
855728 |
20% Upregulated |
Hypoxanthine guanine PhosphoribosylTransferase |
HPT1 |
852008 |
Upregulated |
Idh2p |
IDH2 |
854303 |
30% Upregulated |
INositol polyphosphate 5-Phosphatase |
INP51 |
854815 |
10% Upregulated |
Inositol Polyphosphate Kinase |
IPK1 |
851910 |
40% Upregulated |
Insensitive to KIller toxin |
IKI3 |
851100 |
Upregulated |
Iron-sulfur cluster assembly factor for Biotin synthase and Aconitase-like mitochondrial proteins |
IBA57 |
853586 |
50% Upregulated |
Isocitrate dehydrogenase |
LYS12 |
854714 |
Upregulated |
Isocitrate DeHydrogenase |
IDH1 |
855691 |
15% Upregulated |
Isocitrate Dehydrogenase, NADP-specific |
IDP1 |
851493 |
15% Upregulated |
Isw2p |
ISW2 |
854480 |
24% Upregulated |
Itc1p |
ITC1 |
852744 |
18% Upregulated |
KARyogamy |
KAR3 |
856263 |
55% Upregulated |
Las Seventeen Binding protein |
LSB3 |
850580 |
40% Upregulated |
Las Seventeen Binding protein |
LSB1 |
853037 |
30% Upregulated |
Las Seventeen Binding protein |
LSB6 |
853345 |
50% Upregulated |
LEUcine biosynthesis |
LEU2 |
850342 |
Upregulated |
LEUcine biosynthesis |
LEU3 |
851172 |
Upregulated |
LINk |
LIN1 |
856561 |
40% Upregulated |
LOCalization of ASH1 mRNA |
LOC1 |
850551 |
40% Upregulated |
Long Chronological Lifespan |
LCL1 |
856051 |
Upregulated |
Long Chronological Lifespan 2 |
LCL2 |
850794 |
Upregulated |
Long Chronological Lifespan 3 |
LCL3 |
852795 |
Upregulated |
Long-Chain Base |
LCB3 |
853307 |
Upregulated |
lysine--tRNA ligase MSK1 |
MSK1 |
855651 |
12% Upregulated |
mannosyltransferase YUR1 |
YUR1 |
853302 |
19% Upregulated |
Mep2p |
MEP2 |
855580 |
Upregulated |
Mep3p |
MEP3 |
856260 |
Upregulated |
Methylene Tetrahydrafolate Dehydrogenase |
MTD1 |
853955 |
Upregulated |
Mir1p |
MIR1 |
853540 |
25% Upregulated |
mitochondrial 54S ribosomal protein IMG1 |
IMG1 |
850413 |
23% Upregulated |
mitochondrial 54S ribosomal protein IMG2 |
IMG2 |
850434 |
28% Upregulated |
mitochondrial 54S ribosomal protein YmL33 |
MRPL33 |
855330 |
16% Upregulated |
mitochondrial 54S ribosomal protein YmL40 |
MRPL40 |
855930 |
21% Upregulated |
mitochondrial 54S ribosomal protein YmL49 |
MRPL49 |
853349 |
25% Upregulated |
Mitotic Arrest-Deficient |
MAD2 |
853422 |
50% Upregulated |
Mns1p |
MNS1 |
853595 |
Upregulated |
Mub1p |
MUB1 |
855126 |
29% Upregulated |
MUddled Meiosis |
MUM2 |
852348 |
Upregulated |
N-Myristoyl Transferase |
NMT1 |
850892 |
50% Upregulated |
Nat4p |
NAT4 |
855091 |
21% Upregulated |
Nitrogen Network Kinase |
NNK1 |
853683 |
Upregulated |
OligoPeptide Transporter 2 |
OPT2 |
856324 |
23% Upregulated |
Outer Membrane |
OM45 |
854670 |
Upregulated |
p53 Regulatory Kinase |
PRK1 |
854713 |
30% Upregulated |
Pachytene CHeckpoint |
PCH2 |
852484 |
50% Upregulated |
PaXillin-Like protein |
PXL1 |
853965 |
Upregulated |
PEroXisome related |
PEX25 |
855991 |
Upregulated |
Pet127p |
PET127 |
854182 |
35% Upregulated |
Pet309p |
PET309 |
850756 |
25% Upregulated |
Pho85 CycLin |
PCL7 |
854761 |
Upregulated |
PHOsphate metabolism |
PHO89 |
852599 |
50% Upregulated |
PhosphatidylInositol(3)-phosphate Binding |
PIB1 |
851908 |
25% Upregulated |
phosphoadenylyl-sulfate reductase (thioredoxin) |
MET16 |
856296 |
Upregulated |
PhosphoRibosylpyrophosphate Synthetase |
PRS3 |
856375 |
50% Upregulated |
PIK-related protein kinase and rapamycin target |
TOR1 |
853529 |
30% Upregulated |
Pkb-activating Kinase Homolog |
PKH1 |
852101 |
15% Upregulated |
Pkb-activating Kinase Homolog |
PKH3 |
852077 |
10% Upregulated |
Pkb-activating Kinase Homolog |
PKH2 |
854053 |
20% Upregulated |
Plasma Membrane ATPase Related |
PMR1 |
852709 |
40% Upregulated |
Pleiotropic Drug Resistance |
PDR18 |
855807 |
Upregulated |
Pmt7p |
PMT7 |
851902 |
30% Upregulated |
protein disulfide isomerase MPD1 |
MPD1 |
854462 |
17% Upregulated |
Protein kinase activator found in a complex containing Snf1p and members of the Sip1p/Sip2p/Gal83p f |
SNF4 |
852763 |
20% Upregulated |
Protein kinase that regulates signal transduction activity and G1 progression |
SCH9 |
856612 |
300% Upregulated |
PseudoHyphal Determinant |
PHD1 |
853823 |
20% Upregulated |
Psi+ INducibility |
PIN3 |
856277 |
15% Upregulated |
Pst2p |
PST2 |
851596 |
36% Upregulated |
putative dolichyl-phosphate-mannose-protein mannosyltransferase PMT5 |
PMT5 |
851464 |
21% Upregulated |
putative mitochondrial 54S ribosomal protein |
MRX14 |
851692 |
12% Upregulated |
putative ubiquitin-protein ligase UBR2 |
UBR2 |
850711 |
67% Upregulated |
PyriDoXine auxotrophy |
PDX3 |
852323 |
50% Upregulated |
Rcm1p |
RCM1 |
855709 |
Upregulated |
Rcy1p |
RCY1 |
853226 |
Upregulated |
Rec8p |
REC8 |
856115 |
20% Upregulated |
Regulator of heterotrimeric G protein Signaling |
RGS2 |
854274 |
35% Upregulated |
Replication In Mitochondria |
RIM1 |
850395 |
20% Upregulated |
Resistance to Congo Red 2 |
RCR2 |
851566 |
18% Upregulated |
Restores Glucose Transport |
RGT1 |
853828 |
Upregulated |
Restores Glucose Transport |
RGT2 |
851417 |
Upregulated |
Rfx1p |
RFX1 |
850873 |
20% Upregulated |
ribosomal 40S subunit protein S10B |
RPS10B |
855270 |
Upregulated |
ribosomal 40S subunit protein S12 |
RPS12 |
854551 |
38% Upregulated |
ribosomal 40S subunit protein S18A |
RPS18A |
852061 |
15% Upregulated |
ribosomal 40S subunit protein S18B |
RPS18B |
854982 |
15% Upregulated |
ribosomal 40S subunit protein S6B |
RPS6B |
852479 |
45% Upregulated |
ribosomal 60S subunit protein L10 |
RPL10 |
850764 |
24% Upregulated |
ribosomal 60S subunit protein L16B |
RPL16B |
855655 |
23% Upregulated |
ribosomal 60S subunit protein L26A |
RPL26A |
851058 |
22% Upregulated |
ribosomal 60S subunit protein L2B |
RPL2B |
854794 |
38% Upregulated |
ribosomal 60S subunit protein L35A |
RPL35A |
851336 |
41% Upregulated |
ribosomal 60S subunit protein L6B |
RPL6B |
851169 |
40% Upregulated |
Ribosomal Protein of the Large subunit |
RPL33B |
854409 |
15% Upregulated |
Ribosomal Protein of the Large subunit |
RPL35B |
851419 |
25% Upregulated |
Ribosomal Protein of the Large subunit |
RPL8B |
850682 |
25% Upregulated |
Ribosomal Protein of the Large subunit |
RPL12A |
856656 |
35% Upregulated |
Ribosomal Protein of the Large subunit |
RPL37B |
852111 |
35% Upregulated |
Ribosomal Protein of the Large subunit |
RPL19A |
852379 |
50% Upregulated |
Ribosomal Protein of the Large subunit |
RPL9A |
852730 |
30% Upregulated |
Ribosomal Protein of the Large subunit |
RPL9B |
855658 |
30% Upregulated |
Ribosomal Protein of the Large subunit |
RPL20B |
854489 |
50% Upregulated |
Ribosomal Protein of the Large subunit |
RPL19B |
852254 |
20% Upregulated |
Ribosomal Protein of the Large subunit |
RPL12B |
852026 |
20% Upregulated |
Ribosomal Protein of the Large subunit |
RPL1B |
852742 |
20% Upregulated |
Ribosomal Protein of the Large subunit |
RPL4A |
852319 |
20% Upregulated |
Ribosomal Protein of the Large subunit |
RPL21B |
856026 |
50% Upregulated |
Ribosomal Protein of the Large subunit |
RPL22A |
850750 |
90% Upregulated |
Ribosomal Protein of the Large subunit |
RPL23A |
852191 |
40% Upregulated |
Ribosomal Protein of the Large subunit |
RPL29 |
850592 |
35% Upregulated |
Ribosomal Protein of the Large subunit |
RPL34B |
854759 |
60% Upregulated |
Ribosomal Protein of the Large subunit |
RPL43B |
853557 |
30% Upregulated |
Ribosomal Protein of the Large subunit |
RPL7A |
852804 |
40% Upregulated |
Ribosomal Protein of the Large subunit |
RPL13A |
851477 |
30% Upregulated |
Ribosomal Protein of the Large subunit |
RPL21A |
852489 |
30% Upregulated |
Ribosomal Protein of the Small subunit |
RPS11A |
851589 |
30% Upregulated |
Ribosomal Protein of the Small subunit |
RPS6A |
856015 |
30% Upregulated |
Ribosomal Protein of the Small subunit |
RPS26B |
856868 |
20% Upregulated |
Ribosomal Protein P1 Beta |
RPP1B |
851427 |
40% Upregulated |
Ribosomal Protein P2 Beta |
RPP2B |
851990 |
55% Upregulated |
Rieske Iron-sulfur Protein |
RIP1 |
856689 |
15% Upregulated |
RNase H |
RNH201 |
855652 |
50% Upregulated |
RPO31 |
RPO31 |
854283 |
Upregulated |
Rtg3p |
RTG3 |
852171 |
Upregulated |
S-AdenosylMethionine requiring |
SAM1 |
850877 |
20% Upregulated |
SAGA histone acetyltransferase complex subunit SGF11 |
SGF11 |
856060 |
26% Upregulated |
Scp1p |
SCP1 |
854549 |
65% Upregulated |
SECretory |
SEC28 |
854734 |
20% Upregulated |
Silent information regulator |
SIR4 |
851813 |
Upregulated and Downregulated |
similar to the mammalian TPA Induced Sequence gene family |
TIS11 |
850827 |
30% Upregulated |
SIt4 Suppressor |
SIS2 |
853946 |
50% Upregulated |
Sna3p |
SNA3 |
853290 |
27% Upregulated |
Something About Silencing |
SAS3 |
852228 |
Upregulated |
Something About Silencing |
SAS4 |
851762 |
Upregulated |
Sorting NeXin |
SNX3 |
854539 |
Upregulated |
Sorting NeXin |
SNX41 |
852035 |
Upregulated |
Sov1p |
SOV1 |
855088 |
30% Upregulated |
SPOrulation |
SPO22 |
854737 |
Upregulated |
SPorulation Specific |
SPS1 |
852135 |
25% Upregulated |
Stability of Eisosomes Guaranteed |
SEG2 |
853756 |
20% Upregulated |
Stress-inducible Dual specificity Phosphatase |
SDP1 |
854693 |
25% Upregulated |
Stress-Seventy subfamily A |
SSA3 |
852203 |
50% Upregulated |
succinate dehydrogenase assembly factor SDH5 |
SDH5 |
854083 |
28% Upregulated |
succinate dehydrogenase flavoprotein subunit SDH1 |
SDH1 |
853709 |
25% Upregulated |
succinate dehydrogenase iron-sulfur protein subunit SDH2 |
SDH2 |
850685 |
21% Upregulated |
Sucrose NonFermenting |
SNF3 |
851333 |
Upregulated |
Suppressor gene for FLocculation |
SFL1 |
854307 |
Upregulated |
Suppressor Of Kinase |
SOK1 |
851569 |
50% Upregulated |
Suppressor of Kre Null |
SKN1 |
853045 |
60% Upregulated |
SuPpressor of Ty's |
SPT4 |
852955 |
40% Upregulated |
Suv3p |
SUV3 |
856078 |
25% Upregulated |
SWItching deficient |
SWI5 |
851724 |
20% Upregulated |
Tcb3p |
TCB3 |
854903 |
18% Upregulated |
Temperature dependent Organization in Mitotic nucleus |
TOM1 |
852068 |
30% Upregulated |
Tpk2p |
TPK2 |
855898 |
25% Upregulated |
TransALdolase |
TAL1 |
851068 |
20% Upregulated |
transcription factor MIG1 |
MIG1 |
852848 |
Downregulated |
Translation Initiation Factor |
TIF4631 |
853071 |
20% Upregulated |
Translation Initiation Factor |
TIF4632 |
852833 |
20% Upregulated |
Translation Machinery Associated |
TMA19 |
853809 |
30% Upregulated |
TriacylGlycerol Lipase |
TGL3 |
855361 |
Upregulated |
trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) |
GRE3 |
856504 |
100% Upregulated |
TRna Methyltransferase |
TRM9 |
854994 |
Upregulated |
UBiquitin-Conjugating |
UBC12 |
851015 |
50% Upregulated |
Ubx2p |
UBX2 |
854995 |
24% Upregulated |
Up in StarVation |
USV1 |
855871 |
Upregulated |
Upstream Activation Factor subunit |
UAF30 |
854470 |
Upregulated |
Ure2p |
URE2 |
855492 |
20% Upregulated |
URidine Hydrolase |
URH1 |
852009 |
24% Upregulated |
Uth1p |
UTH1 |
853916 |
15% Upregulated |
Utilization of GAba |
UGA1 |
852902 |
50% Upregulated |
Utilization of GAba |
UGA3 |
851384 |
75% Upregulated |
Vacuolar Basic Amino acid transporter |
VBA5 |
853980 |
Upregulated |
Vacuolar Protein Sorting |
VPS5 |
854235 |
Upregulated |
Vacuolar Protein Sorting |
VPS70 |
853590 |
Upregulated |
Vacuolar Protein Sorting |
VPS75 |
855475 |
Upregulated |
Yeast Protein Two |
YPT6 |
850966 |
30% Upregulated |
Yeast Tat-binding Analog |
YTA7 |
853186 |
50% Upregulated |
Yeast vaccinia virus VH1 Homolog |
YVH1 |
854844 |
50% Upregulated |
Ysc84p |
YSC84 |
856409 |
25% Upregulated |
Zds1p |
ZDS1 |
855316 |
37% Upregulated |
ZWischenFerment |
ZWF1 |
855480 |
Upregulated |
Reference: HAGR |