Aging and Senescence

     D melanogaster
Dose
Name of Formulation Avg/Med Lifespan Change (%) -96267.9 Max Lifespan Change (%) -94.993 Strain Significance (Yes: Y, No: N) Reference
Carnosine 200 mg/l D-32 N 12447464
Cocoa 100 g/l medium rosy^+5 N 19083435
Cocoa 50 g/l medium rosy^+5 Y 19083435
Curcumin 10 mM Ra N 23063786
Curcumin 200 mM Ra Y 23063786
Curcumin 0.5 mg/g Wild 1-A N 23675008
Nordihydroguaiaretic acid 1 mg/ml Oregon-R-C N 25380600
Rhodiola rosea extract 30 mg/mL every other day 28.6 ND 9825229
Rhodiola rosea extract 30 mg/mL every other day 42.9 ND 9825229
Tartaric acid 0.1M -72 Oregon R ND 110607
Sodium borate 0.01 M -69.2 Oregon R Y 7889879
Calcium lactate 0.1 M -66.1 Oregon R ND 110607
Metformin 100 mM -66 Dahomey Y 23077661
Calcium gluconate 0.1 M -56.6 Oregon R ND 110607
Sodium borate 0.05 M -51.9 Oregon R Y 7889879
Paraquat 1 mM -41.4 Dahomey Y 27076081
Rutin 800 µM -38 Canton-S Y 28389882
Lactic acid 1 M -32.7 Oregon R ND 110607
Metformin 100 mM -31 Dahomey Y 23077661
Curcumin 100 mM -23.4 Ra N 23063786
Curcumin 100 mM -23.4 Ra Y 26136617
Rutin 600 µM -23 Canton-S Y 28389882
Caffeine 0.03% -22.86 -11.6 Canton-S Y 29093334
Metformin 50 mM -22 Dahomey Y 23077661
Sodium borate 1 mM -21.2 Oregon R Y 7889879
Rotenone 100 µM -21.14 Dahomey Y 27076081
Caffeine 0.05% -17.14 -11.6 Canton-S Y 29093334
Curcumin 100 mM -17 -3 Ra Y 26136617
Curcumin 100 mM -17 3 Ra Y 23063786
Rutin 800 µM -16.66 Canton-S Y 28389882
Galactose 6.50% -15.9 -17.1 Y 15547319
Resveratrol 32 µM -15.4 Canton S N 17875315
Taurine 1.50% -14.29 -23.19 Canton-S Y 29093334
Resveratrol 32 µM -13.9 Canton S Y 17875315
Quercetin 1 µM -13.79 -14.62 Canton S Y 28066251
Rutin 600 µM -13.33 Canton-S Y 28389882
Calcium gluconate 0.01 M -13.2 Oregon R ND 110607
Galactose 6.50% -12.6 -12.9 Y 15547319
Quercetin 0.5 µM -12 -13.84 Canton S Y 28066251
Rhodiola rosea 30 mg/ml -11.9 -16.4 IF Y 24472572
Epicatechin 1 µM -11.44 -2.21 Canton S Y 28066251
Sodium butyrate 100 mM -10.9 Ra Y 23044027
Calcium lactate 0.01 M -10.7 Oregon R ND 110607
Curcumin 100 mM -10.2 Ra N 23063786
Quercetin 1 µM -10.2 -8.21 Canton S Y 28066251
Caffeine 0.01 mg/ml -10.1 Oregon R N 8326745
Resveratrol 500 µmol/L -9.9 -5.28 w1118 N 29324667
Gluconic acid 1 M -9.3 Oregon R ND 110607
Sodium butyrate 10 mM -9.1 Ra N 23044027
Rhodiola rosea 30 mg/ml -9.1 -12.2 IF Y 24472572
Epicatechin 0.3µM -9.08 -10 Canton S Y 28066251
Catechin 0.1 mg/ml -8.5 Oregon R N 8326745
Resveratrol 10 µM -8.3 Canton S Y 17875315
Resveratrol 1000 µM -8.3 Canton S N 17875315
Curcumin 100 mM -8.2 25 Ra Y 23063786
Resveratrol 10 µM -7.7 Canton S Y 17875315
Resveratrol 3.2 µM -7.4 Dahomey N 17875315
Resveratrol 32 µM -7.4 Dahomey N 17875315
Resveratrol 1000 µM -7.4 Dahomey N 17875315
Resveratrol 200 µM -7.4 Dahomey N 17875315
Metformin 25 mM -7 Dahomey Y 23077661
Resveratrol 1 µM -6.8 Canton S N 17875315
Epicatechin 0.3µM -6.49 -5.22 Canton S Y 28066251
Sodium butyrate 100 mM -6.3 Ra N 23044027
Sodium butyrate 10 mM -6.3 Ra N 23044027
Metformin 50 mM -6 Dahomey N 23077661
Metformin 10 mM -6 Dahomey N 23077661
Metformin 25 mM -6 Dahomey N 23077661
Resveratrol 1 µM -5.6 Dahomey N 17875315
Resveratrol 10 µM -5.6 Dahomey Y 17875315
Resveratrol 1000 µM -5.6 Dahomey N 17875315
Gluconic acid 0.1 M -5.2 Oregon R ND 110607
Catechin 1 mg/ml -5.1 Oregon R N 8326745
Catechin 0.01 mg/ml -5.1 Oregon R N 8326745
Quercetin 0.3µM -5.09 -8.2 Canton S Y 28066251
Quercetin 0.5 µM -4.55 -6.7 Canton S Y 28066251
Resveratrol 10 µM -4.5 Canton S N 17875315
Resveratrol 200 µM -4.5 Canton S N 17875315
Metformin 2.5 mM -4 Dahomey N 23077661
Epicatechin 1 µM -3.78 -4.48 Canton S Y 28066251
Calcium gluconate 0.001 M -3.7 Oregon R ND 110607
Resveratrol 1 µM -3.7 Dahomey N 17875315
Resveratrol 100 µM -3.7 Dahomey N 17875315
Resveratrol 10 µM -3.4 Canton S N 17875315
Resveratrol 1 µM -3.4 Canton S N 17875315
Resveratrol 32 µM -3.4 Canton S Y 17875315
Resveratrol 100 µM -3.4 Canton S N 17875315
Resveratrol 3.2 µM -3.4 Canton S N 17875315
Resveratrol 100 µM -3.4 Canton S N 17875315
Resveratrol 200 µM -3.4 Canton S N 17875315
Resveratrol 1000 µM -3.4 Canton S N 17875315
Resveratrol 3.2 µM -3.4 Dahomey N 17875315
Resveratrol 100 µM -3.4 Dahomey N 17875315
Resveratrol 32 µM -3.4 Dahomey N 17875315
Caffeine 1 mg/ml -3.3 Oregon R N 8326745
Metformin 10 mM -3 Dahomey N 23077661
Resveratrol 3.2 µM -3 Dahomey N 17875315
Tannic acid 1 mg/ml -2.9 Oregon R N 8326745
Resveratrol 3.2 µM -2.8 Canton S N 17875315
Resveratrol 3.2 µM -2.8 Dahomey N 17875315
Resveratrol 32 µM -2.8 Dahomey N 17875315
Resveratrol 200 µM -2.8 Dahomey N 17875315
Resveratrol 1000 µM -2.8 Dahomey N 17875315
Quercetin 0.3µM -2.8 -13.07 Canton S Y 28066251
Resveratrol 200 µM -2.1 Canton S N 22083438
Resveratrol 32 µM -2 Canton S N 17875315
Resveratrol 1000 µM -2 Canton S N 17875315
Lactic acid 0.5M -1.9 Oregon R ND 110607
Gluconic acid 0.001 M -1.8 Oregon R ND 110607
Resveratrol 200 µM -1.5 Canton S N 22083438
Resveratrol 100 µM -1.4 Dahomey Y 17875315
Resveratrol 200 µM -1.4 Dahomey Y 17875315
Curcumin 50 µM -1 Canton S ND 25173182
AU701 0.30% -0.7 Canton S N 24305778
CU701 0.30% 0 Canton S N 24305778
Gluconic acid 0.01 M 0 Oregon R ND 110607
Gluconic acid 0.001 M 0 Oregon R ND 110607
Gluconic acid 0.5M 2x/week 0 Oregon R ND 110607
Metformin 1 mM 0 Dahomey N 23077661
Metformin 5 mM 0 Dahomey N 23077661
Metformin 5 mM 0 Dahomey N 23077661
Metformin 2.5 mM 0 Dahomey N 23077661
Resveratrol 200 µM 0 Canton S N 17875315
Resveratrol 1 µM 0 Canton S N 17875315
Resveratrol 3.2 µM 0 Canton S N 17875315
Resveratrol 200 µM 0 Canton S N 17875315
Resveratrol 100 µM 0 Canton S N 17875315
Resveratrol 10 µM 0 Canton S N 17875315
Resveratrol 100 µM 0 Canton S N 17875315
Resveratrol 1 µM 0 Canton S N 17875315
Resveratrol 200 µM 0 Dahomey N 17875315
Resveratrol 10 µM 0 Dahomey N 17875315
Resveratrol 100 µM 0 Dahomey N 17875315
Resveratrol 32 µM 0 Dahomey N 17875315
Resveratrol 10 µM 0 Dahomey N 17875315
Sodium borate 1 µM 0 Oregon R N 7889879
Tannic acid 1 mg/ml 0 Oregon R N 8326745
Tannic acid 0.1 mg/ml 0 Oregon R N 8326745
Tartaric acid 0.001 M 0 Oregon R ND 110607
Epicatechin 0.5 µM 0 2.24 Canton S N 28066251
Aronia extract 1 mg/mL 0 7.77 Canton-S N 30263675
Resveratrol 100 µM 1 Canton S N 22083438
Proanthocyanidins from Kunlun Chrysanthemum flowers 1 5.1 Oregon R+ N 25628774
AU701 0.30% 1.2 Canton S N 24305778
Resveratrol 1 µM 1.4 Dahomey N 17875315
Cynomorium songaricum Rupr. 10 mg/ml 1.5 Canton S N 22844336
Sodium borate 0.01 mM 1.5 Oregon R Y 7889879
Caffeine 0.1 mg/ml 1.7 Oregon R N 8326745
Calcium lactate 0.001 M 1.8 Oregon R ND 110607
Epicatechin 0.01 mg/ml 1.8 Oregon R N 8326745
Resveratrol 100 µM 1.8 Canton S N 22083438
Curcumin 5 µM 2 Canton S ND 25173182
Resveratrol 200 µM 2 Canton S N 17875315
Vitamin E 100 µg/ml 2 Canton S Y 17169403
Cynomorium songaricum Rupr. 20 mg/ml 2.2 Canton S N 22844336
Rhodiola rosea 2.5 mg/ml 2.4 -6 IF N 24472572
Platanus orientalis Extract 10 µg/ml 2.43 7.46 Oregon R Y 28887920
Morphine 2.6 Oregon R Y 21061062
Resveratrol 1 µM 2.8 Canton S N 17875315
Resveratrol 100 µM 2.8 Canton S N 17875315
Resveratrol 100 µM 2.8 Dahomey N 17875315
Resveratrol 3.2 µM 2.8 Dahomey N 17875315
Turmeric powder 2.5 g/L 2.9 Y 24967413
Curcumin 50 µM 3 Canton S ND 25173182
Resveratrol 1000 µM 3 Dahomey N 17875315
Sodium borate 0.1 mM 3 Oregon R Y 7889879
N-(3-(aminomethyl)benzyl)acetamidine 0.03 µM 3 13 Canton S Y 24096697
Curcumin 0.2 mg/g 3.01 4.91 Canton-S N 30488487
Epitalon 5*10^-6 % 3.2 Canton S N 11087911
Epitalon 1*10^-6 % 3.2 Canton S N 11087911
Morphine 3.2 Oregon R Y 21061062
Proanthocyanidins from Kunlun Chrysanthemum flowers 3.2 2.9 Oregon R+ N 25628774
Platanus orientalis Extract 1 µg/ml 3.26 1.49 Oregon R Y 28887920
Resveratrol 1000 µM 3.4 Canton S N 17875315
Resveratrol 10 µM 3.4 Dahomey N 17875315
Lactic acid 0.01M 3.6 Oregon R ND 110607
Lactic acid 0.001 M 3.6 Oregon R ND 110607
Cynomorium songaricum Rupr. 30 mg/ml 3.7 Canton S N 22844336
Epicatechin 0.1 mg/ml 3.7 Oregon R N 8326745
N-Acetyl Cysteine 1 mM 3.7 1.6 Canton-S Y 30243020
Gluconic acid 0.25M 2x/week 3.8 Oregon R ND 110607
Gluconic acid 0.01M 2x/week 3.8 Oregon R ND 110607
Curcumin 25 µM 4 Canton S ND 25173182
Metformin 1 mM 4 Dahomey N 23077661
Sodium butyrate 100 mM 4.2 Ra Y 23044027
Casein 1.25% 4.34 0 Canton-S Y 27388939
Resveratrol 3.2 µM 4.5 Canton S N 17875315
Resveratrol 1000 µM 4.5 Canton S N 17875315
Rosa damascena extract 4.5 7.4 w1118 N 21928072
Torin 1 1 µM 4.55 3.8 Dahomey Y 29329306
Glucomannan Hydrolysate 0.25% w/v 4.6 DGRP-40 Y 30137218
Melatonin 0.08% per unit mass culture medium 4.8 Canton S Y 10100152
Wortmannin 5 µM 5 Canton S Y 24096697
Prunetin 25 µM 5.19 7.17 w1118 Y 26538555
Gluconic acid 0.01 M 5.3 Oregon R ND 110607
Proanthocyanidins from Kunlun Chrysanthemum flowers 5.3 4.7 Oregon R+ N 25628774
CU701 0.30% 5.4 Canton S Y 24305778
Melatonin 0.08% per unit mass culture medium 5.5 Canton S Y 10100152
N-Acetyl Cysteine 10 nM 5.6 4.7 Canton-S Y 30243020
N-Acetyl Cysteine 100 µM 5.6 10.9 Canton-S Y 30243020
Korean red ginseng tonic 0.12 µg/ml 5.7 w1118 N 24265871
Proanthocyanidins from Kunlun Chrysanthemum flowers 5.7 3.1 Oregon R+ N 25628774
Emblica officinalis 20 ml 5.9 Y 24967413
Emblica officinalis 30 ml 5.9 Y 24967413
Green tea extract 1 mg/ml 5.9 5.3 Oregon-R-C Y 17440995
CU701 0.30% 6 Canton S N 24305778
Curcumin 5 µM 6 Canton S ND 25173182
Minocycline 0.36mM 6 w1118 Y 29152127
Tartaric acid 0.01M 6 Oregon R ND 110607
Curcumin 0.5 mg/g 6.2 -5.2 Oregon R N 22653297
Fucoxanthin 1 µM 6.2 0 Canton S Y 29504896
Cranberry anthocyanin extract 5 mg/ml 6.3 0 Oregon-R-C Y 26159161
Curcumin 0.2 mg/g 6.74 8.77 Canton-S Y 30488487
Rhodiola rosea 2.5 mg/ml 6.8 -2.9 IF N 24472572
Resveratrol 1 µM 6.9 Dahomey N 17875315
Resveratrol 1000 µM 6.9 Dahomey N 17875315
Epicatechin 0.5 µM 6.95 3.08 Canton S Y 28066251
Metformin 5 mM 7 Dahomey N 23077661
Tea (Camellia sinensis) extract 1:10 dilution 7 Oregon R Y 8326745
Epitalon 1*10^-9 % 7.1 Canton S N 11087911
Gluconic acid 0.01 M 7.2 Oregon R ND 110607
Glucomannan Hydrolysate 0.25% w/v 7.3 DGRP-136 Y 30137218
Epicatechin 1 mg/ml 7.4 Oregon R N 8326745
N-Acetyl Cysteine 1 µM 7.4 4.7 Canton-S Y 30243020
Epicatechin 1 µM 7.5 Canton S Y 28066251
Minocycline 0.36mM 7.7 Canton S Y 29152127
Green tea extract 5 mg/ml 7.8 5.3 Oregon-R-C Y 17440995
Lactic acid 0.001 M 8 Oregon R ND 110607
Pomegrenate juice 0.1 8 Canton S Y 25566518
Indirubin 3 mM 8.2 Oregon R Y 22363408
Resveratrol 3.2 µM 8.2 Canton S N 17875315
Sodium butyrate 100 mM 8.3 Ra Y 23044027
Sodium butyrate 10 mM 8.3 Ra Y 23044027
Sodium butyrate 10 mM 8.3 12 Ra Y 26136617
2,5-Dimethyl-Celecoxib 0.5 µM 8.4 11.32 Dahomey Y 28025308
Freeze dried royal jelly 1% w/v 8.5 -4 Oregon R Y 23132575
Baicalein 0.04mg/ml 8.53 5.7 w1118 Y 26778291
Green tea extract Instead of water 8.6 Oregon R Y 8326745
Pinitol 8.7 Canton S Y 22843669
Crocus Sativus Aqueous Extract 1% 8.8 w1118 Y 27878268
Royal Jelly Protein 1.25% 8.96 6.9 Canton-S Y 27388939
Curcumin 25 µM 9 Canton S ND 25173182
2,5-Dimethyl-Celecoxib 0.5 µM 9.07 3.39 Dahomey Y 28025308
Beta-Guanidinopropionic acid 900 mM 9.1 w1118 Y 26120775
Resveratrol 32 µM 9.1 Canton S N 17875315
Resveratrol 32 µM 9.1 Dahomey N 17875315
Gluconic acid 0.5 M 9.3 Oregon R ND 110607
N-Acetyl Cysteine 100 nM 9.3 7.8 Canton-S Y 30243020
Baicalein 1 mg/ml 9.32 4.66 w1118 Y 26778291
Sodium borate 0.25 mM 9.5 Oregon R N 7889879
Apple polyphenols NA 10 Oregon R Y 21319854
Black tea extract 10 mg/ml 10 Y 19770032
Blueberry extract 5 mg/ml 10 Y 22197903
Glucomannan Hydrolysate 0.25% w/v 10 DGRP-85 Y 30137218
Pyrrolidine dithiocarbamate 125 µM 10 Canton S Y 24096697
Glucomannan Hydrolysate 0.25% w/v 10.1 DGRP-38 Y 30137218
J147 0.1µM 10.35 1.39 (w1118/+) Y 29316249
Cranberry anthocyanin extract 20 mg/ml 10.4 5.1 Oregon-R-C Y 26159161
Epitalon 1*10^-7 % 10.8 Canton S Y 11087911
jujube fruit powder 150 mg/ml 11.1 w1118 Y 28251407
Epitalon 5*10^-6 % 11.3 Canton S Y 11087911
AU701 0.30% 11.4 Canton S Y 24305778
Cynomorium songaricum Rupr. 30 mg/ml 11.4 Canton S Y 22844336
Lutein 0.1 mg/ml 11.4 Y 23993264
Glucomannan Hydrolysate 0.25% w/v 11.7 Oregon-R Y 30137218
Epitalon 1*10^-7 % 11.8 Canton S Y 11087911
Rhodiola rosea 30 mg/mL 11.9 Y 17990971
Tert-butyl hydroperoxide 5 mM 11.9 w iso31 Y 29515102
Epitalon 1*10^-8 % 12 Canton S Y 11087911
Lactic acid 0.01M 12 Oregon R ND 110607
Pyrrolidine dithiocarbamate 125 µM 12 Canton S Y 24096697
Sesame 2 mg/ml 12 Oregon R Y 23291977
Trametinib 15.6 µM 12 white Dahomey Y 26119340
Alpha-lipoic acid 0.01% 12 5 Canton S ND 15328413
Resveratrol 200 µM 12.1 Dahomey N 17875315
Tert-butyl hydroperoxide 2.5 mM 12.1 w iso31 Y 29515102
Tea (Camellia sinensis) extract Instead of water 12.2 Oregon R Y 8326745
Tert-butyl hydroperoxide 1 mM 12.2 w iso31 Y 29515102
Gluconic acid 0.1 M 12.3 Oregon R ND 110607
Stachys lavandulifolia ethanol extract 4 µl/100 ml media 12.4 6.4 Oregon R Y 20738162
Royal Jelly Protein 2.50% 12.43 5.17 Canton-S Y 27388939
Pinitol 12.5 Canton S Y 22843669
Sodium butyrate 10 mM 12.5 Ra Y 23044027
J147 2 µM 12.5 -8.33 (w1118/+) Y 29316249
Curcumin 1 mg/g 12.6 13 Oregon R Y 22653297
ursolic acid 50 µmol/L 12.78 w1118 Y 30496629
Epitalon 1*10^-6 % 12.8 Canton S Y 11087911
Rapamycin 10 µM 12.98 -2.89 Dahomey Y 28025308
3,4-dihydroxybenzaldehyde 0.3 mM 13 yw (y1w67c23) Y 22809229
3,4-dihydroxybenzaldehyde 3 mM 13 yw (y1w67c23) Y 22809229
Quercetin 1 µM 13 Canton-S Y 28066251
Rapamycin 200 µM 13 white Dahomey Y 20074526
Quercetin 1 µM 13 6 Canton S Y 28066251
Lithium Chloride 10 mM 13 13 Dahomey Y 27068460
Platanus orientalis Extract 0.1µg/ml 13.02 11.94 Oregon R Y 28887920
Beta-Guanidinopropionic acid 900 mM 13.3 w1118 Y 26120775
Epitalon 1*10^-8 % 13.4 Canton S Y 11087911
Glucomannan Hydrolysate 0.25% w/v 13.4 DGRP-21 Y 30137218
Korean red ginseng tonic 12 µg/ml 13.5 w1118 Y 24265871
Dimethyl Sulfide 10 µM 13.56 w1118 Y 27790859
Minocycline 0.05mM 13.6 Canton S Y 29152127
Rhodiola rosea 5 mg/ml 13.6 3.4 IF Y 24472572
Rhodiola rosea 10 mg/ml 13.6 3.9 IF Y 24472572
Royal Jelly Protein 5% 13.87 10.34 Canton-S Y 27388939
Proanthocyanidins from Kunlun Chrysanthemum flowers 13.9 8.9 Oregon R+ Y 25628774
Black rice extract 30 mg/ml 14 Oregon R Y 22930061
Lactic acid 0.1M 14 Oregon R ND 110607
Rhodiola rosea 30 mg/mL 14 Y 17990971
SkQ1 20 pM-20 nM 14 Y 19120018
Vitamin E 0.4% wt/vol 14 Oregon R Y 6821144
LY-294002 5 µM 14 22.5 Canton S Y 20017609
Melatonin 100 µg/ml 14 33 Oregon R Y 11909680
N-acetyl-L-cysteine 1 mg/ml 14.1 15.1 Oregon R ND 9447249
Gluconic acid 0.1 M 14.3 Oregon R ND 110607
Rhodiola rosea 10 mg/ml 14.3 6 IF Y 24472572
LY-294002 5 µM 14.3 16.3 Canton S Y 20017609
HA-1077 10 µM 14.5 Oregon R Y 22363408
Korean red ginseng tonic 1.2 µg/ml 14.5 w1118 Y 24265871
Rosa damascena extract 14.5 6.4 w1118 Y 21928072
Omega-3 Monoacylglyceride Docosahexaenoic acid 0.3 mg/mL 14.58 6.56 w1118 Y 30453574
Omega-3 Monoacylglyceride Docosahexaenoic acid 0.3 mg/mL 14.58 15.32 w1118 Y 30453574
Sodium butyrate 10 mM 14.6 9.1 Ra Y 26136617
Glucomannan Hydrolysate 0.25% w/v 14.88 B18 Y 30137218
Fucoxanthin 1 µM 14.9 4.4 Canton S Y 29504896
D-chiro-inositol 15 Canton S Y 22843669
Pyrrolidine dithiocarbamate 20 mg/l 15 Y 21483034
Aurintricarboxylic acid 0.5 mM 15 0 Oregon R ND 15621204
Resveratrol 10 µM 15.2 Dahomey N 17875315
Resveratrol 1 µM 15.2 Dahomey N 17875315
Cynomorium songaricum Rupr. 10 mg/ml 15.3 Canton S Y 22844336
Aronia extract 2.5 mg/mL 15.38 8.88 Canton-S Y 30263675
Lactic acid 0.25M 15.4 Oregon R ND 110607
Lamotrigine 12 mg/ml 15.4 Ives Y 19430925
Lactic acid 0.1M 15.5 Oregon R ND 110607
Curcumin 0.5 mg/g 15.5 -1.9 Oregon R Y 22653297
Proanthocyanidins from Kunlun Chrysanthemum flowers 15.5 10.4 Oregon R+ Y 25628774
Tiliroside 100 µM 15.56 5.88 Oregon R Y 28887920
Minocycline 0.36mM 15.6 w1118 Y 29152127
Trichostatin A 10 µmol/L 15.6 Canton S ND 15695762
Epigallocatechin-3-gallate 10 mg/ml 15.7 Y 26375250
Minocycline 0.36mM 15.7 Canton S Y 29152127
Tea (Camellia sinensis) extract Instead of water 15.7 Oregon R Y 8326745
Green tea extract 10 mg/ml 15.7 5.3 Oregon-R-C Y 17440995
Epicatechin 1 µM 16 Canton-S Y 28066251
Epithalamin NA 16 Y 9701766
Pyrrolidine dithiocarbamate 20 mg/l 16 Y 21483034
Resveratrol 100 µm 16 Canton S Y 15254550
S,S-trolox-carnosine 50 mg/L 16 Y 20681748
Sevelamer 1% 16 yw Y 22942172
Stachys lavandulifolia ethanol extract 4 µl/100 ml media 16 14 Oregon R Y 20738162
Dimethyl Sulfide 1 mM 16.04 w1118 Y 27790859
Ludwigia octovalvis extract 100 µg/ml 16.1 Canton S Y 24338263
Curcumin 100 mM 16.3 25 Ra Y 23063786
Rapamycin 5 µM 16.35 -2.89 Dahomey Y 28025308
D-chiro-inositol 16.6 Canton S Y 22843669
Epitalon 1*10^-9 % 16.6 Canton S Y 11087911
Everolimus 3 mM 16.6 Oregon R Y 22363408
Tert-butyl hydroperoxide 1 mM 16.7 w iso31 Y 29515102
Rhodiola rosea 5 mg/ml 16.7 6.6 IF Y 24472572
Proanthocyanidins from Kunlun Chrysanthemum flowers 16.8 14 Oregon R+ Y 25628774
N-acetyl-L-cysteine 100 µg/ml 16.8 15.1 Oregon R Y 9447249
CU701 0.30% 16.9 Canton S Y 24305778
Minocycline 0.05mM 16.9 w1118 Y 29152127
Cinnamon Extract 25 mg/ml 17 w1118 Y 25456850
Colanic acid 350 µg/ml 17 OreR Y 28622510
Rutin 200 µM 17 Canton-S Y 28389882
Lamotrigine 12 mg/ml 17.2 Ives Y 19430925
Tyrphostin 9 300-500 µM 17.3 Oregon R Y 22363408
Tert-butyl hydroperoxide 10 mM 17.4 w iso31 Y 29515102
AG-490 300 µM 17.5 Oregon R Y 22363408
Cynomorium songaricum Rupr. 20 mg/ml 17.6 Canton S Y 22844336
Turmeric powder 5 g/L 17.6 Y 24967413
Turmeric powder 7 g/L 17.6 Y 24967413
Nectarine 0.04 17.6 2.7 Canton S Y 21406223
Glucomannan Hydrolysate 0.25% w/v 17.66 Canton-S Y 30137218
Curcumin 250 µM 18 Ives Y 20645870
Erbstatin analog 5 mM 18 Oregon R Y 22363408
HA-1004 1-10 µM 18 Oregon R Y 22363408
Pomegrenate juice 0.1 18 Canton S Y 25566518
Lithium Chloride 25 mM 18 18 Dahomey Y 27068460
Crocus Sativus Aqueous Extract 1% 18.3 w1118 Y 27878268
Tert-butyl hydroperoxide 1.25 mM 18.3 w iso31 Y 29515102
Lithium Chloride 10 mM 18.5 4 Dahomey Y 27068460
Curcumin 100 µM 19 Canton S Y 20645870
Curcumin 10 µM 19 Canton S ND 25173182
Green tea polyphenols 10 mg/ml 19 w1118 Y 25058464
Tyrphostin 1 100-300 µM 19 Oregon R Y 22363408
Carnosine 0.2 mg/l 19.5 D-32 Y 12447464
Tyrphostin AG 1478 100 µM 19.5 Oregon R Y 22363408
Tert-butyl hydroperoxide 5 mM 19.7 w iso31 Y 29515102
Baicalein 0.2mg/ml 19.8 3.97 w1118 Y 26778291
Korean mistletoe extract 50 µg/ml 19.9 Canton S Y 24337961
Carnosine 50 mg/l 20 Y 20681748
Colanic acid 35 µg/ml 20 OreR Y 28622510
KN-93 10-100 µM 20 Oregon R Y 22363408
Resveratrol 100 µm 20 Canton S Y 15254550
Black tea extract Instead of water 20.2 Oregon R Y 8326745
Glucomannan Hydrolysate 0.25% w/v 20.2 B18 Y 30137218
Tea (Camellia sinensis) extract Instead of water 20.2 Oregon R Y 8326745
2,4-dinitrophenol 0.008 20.2 0 Oregon R ND 16266268
Curcumin 1 mg/g 20.3 Wild 1-A Y 23675008
Sodium Yeast Nucleate 5 g/kg 20.3 Oregon Y 18856648
Gluconic acid 0.1 M 20.8 Oregon R ND 110607
Stachys lavandulifolia water extract 12 µl/100 ml media 21.9 8 Oregon R Y 20738162
Stachys lavandulifolia water extract 12 µl/100 ml media 22.1 10.6 Oregon R Y 20738162
Gluconic acid 0.25 M 22.2 Oregon R ND 110607
Rosa damascena extract 22.4 12.7 B Y 21928072
Tyrphostin AG 1295 300-500 µM 22.5 Oregon R Y 22363408
Tert-butyl hydroperoxide 5 mM 22.6 Canton-S Y 29515102
Tert-butyl hydroperoxide 1 mM 22.7 Canton-S Y 29515102
PP2 AG1879 300 µM 22.8 Oregon R Y 22363408
Minocycline 0.05mM 22.9 w1118 Y 29152127
3,4-dihydroxybenzaldehyde 1 mM 23 yw (y1w67c23) Y 22809229
Fisetin 100 µm 23 Canton S Y 15254550
Ibuprofen 1 µM 23 Canton-S Y 28066251
Nordihydroguaiaretic acid 3 mg/ml 23 Oregon-R-C Y 25380600
Quercetin dihydrate 1 mM 23 Oregon R Y 22363408
Lithium Chloride 25 mM 23 13.5 Dahomey Y 27068460
Trichostatin A 10 µM 23.3 37 Canton S Y 15346199
SP600125 10 mM 23.5 Oregon R Y 22363408
Rutin 400 µM 23.52 Canton-S Y 28389882
Rhodiola rosea extract 25 mg/mL 24 16 Y 19634056
Rhodiola rosea extract 25 mg/mL 24 31 Y 19634056
Ludwigia octovalvis extract 100 µg/ml 24.2 Canton S Y 24338263
Dimethyl Sulfide 100 µM 24.25 w1118 Y 27790859
Carnosine 200 mg/l 24.3 D-32 Y 12447464
Lithocholic acid 50 µM 24.94 15.39 w1118 Y 30051966
Simvastatin 240 µM 25 Y 22737247
Curcumin 100 mM 25 20.2 Ra Y 23063786
Curcumin 100 mM 25.5 0 Ra Y 23063786
Curcumin 100 mM 25.5 0 Ra Y 26136617
Curcumin 1 mg/g 25.8 -5.2 Oregon R Y 22653297
Carnosine 2 mg/l 26.4 D-32 Y 12447464
Minocycline 0.05mM 26.7 Canton S Y 29152127
Stachys lavandulifolia ethanol extract 12 µl/100 ml media 26.8 21.3 Oregon R Y 20738162
N-acetyl-L-cysteine 10 mg/ml 26.8 24.5 Oregon R Y 9447249
PD-98059 300-1000 µM 27 Oregon R Y 22363408
Torin 1 0.5 µM 27.27 8.33 Dahomey Y 29329306
Trichostatin A 10 µM 27.3 37.9 Canton S Y 15346199
Calcium Pantothenate 0.5g/kg 27.8 Oregon Y 18856647
Tert-butyl hydroperoxide 5 mM 28.4 Canton-S Y 29515102
Diiodomethane 10 µg/ml 29.3 ND 412727
Rutin 200 µM 30 Canton-S Y 28389882
Spermidine 1 mM 30 w1118 Y 19801973
Cranberry extract 0.02 30.1 Canton S Y 24316039
SB203580 300 µM 30.3 Oregon R Y 22363408
Thiazolidine carboxylic acid 0.3% wt/vol 31 Oregon R Y 6821144
Stachys lavandulifolia ethanol extract 12 µl/100 ml media 31.3 22 Oregon R Y 20738162
Rosa damascena extract 31.7 13 B Y 21928072
Stachys lavandulifolia water extract 20 µl/100 ml media 32 14.9 Oregon R Y 20738162
Cordyceps sinensis oral liquid 0.20 mg/ml 32 15.4 Oregon-K Y 26239097
Curcumin 10 µM 34 Canton S ND 25173182
Staurosporine 30-50 µM 34.8 Oregon R Y 22363408
Stachys lavandulifolia water extract 20 µl/100 ml media 35.6 14 Oregon R Y 20738162
Rhodiola rosea root extract NA 36 w1118 Y 23704949
S,S-trolox-carnosine 50 mg/L 36 Y 20681748
Torin 1 1 µM 36.36 16.6 Dahomey Y 29329306
Cinnamon Extract 75 mg/ml 37 w1118 Y 25456850
Rhodiola rosea root extract NA 40 w1118 Y 23704949
4-phenylbutyrate 5 mM 40 41 Canton S ND 11792861
Epicatechin 0.1 mM/l 42 Canton S Y 21525262
Rutin 400 µM 43.33 Canton-S Y 28389882
Stachys lavandulifolia ethanol extract 20 µl/100 ml media 44.4 8 Oregon R Y 20738162
Curcumin 100 mM 46.8 38 Ra Y 23063786
Curcumin 100 mM 46.8 38 Ra Y 26136617
Minocycline 0.05 mM 49 Oregon Y 22330257
Curcumin 100 mM 49 49 Ra Y 23063786
Torin 1 5 µM 50 13.89 Dahomey Y 29329306
Minocycline 0.87 mM 50 25 Oregon R Y 23185716
Minocycline 0.87 mM 50 66 Oregon R Y 23185716
Rasayana 1 drop 51.1 Oregon-K Y 21836798
Rasayana 1 drop 55 Oregon-K Y 21836798
Stachys lavandulifolia ethanol extract 20 µl/100 ml media 55.7 36 Oregon R Y 20738162
Torin 1 10 µM 59.09 0 Dahomey Y 29329306
Minocycline 0.05 mM 63 Oregon ND 23947005
Guduchi Churna 0.7 g/100 ml 85.91 Oregon-K Y 28827958
Guduchi Churna 0.50g/100ml 155.65 Oregon-K Y 28827958
Guduchi Churna 0.25g/100ml 193.83 Oregon-K Y 28827958
Reference: HAGR