Proteins

CYTOKINES

Cytokine Family Database The Cytokine Family Database (dbCFC) is a collection of EST (Expressed Sequence Tag) records of cytokines deposited in the NCBI GenBank. It provides information about the identification of EST records to cytokine members and related data contained in other databases.

 

HOMOLOGOUS PROTEIN DOMAIN

DOMO DOMO is a database of homologous protein domain families. It was obtained from successive sequence analysis steps including similarity search, domain delineation, multiple sequence alignment and motif construction. 83054 non redundant protein sequences from SWISSPROT and PIR have been analysed yielding a database of 99058 domains clustered into 8877 multiple sequence alignments.

 

PROTEIN DATABASES

A Library of Protein Family Cores Structural alignments of protein families and computed average core structures for each family. The core structures can be divided into residues with low spatial variation and those with high spatial variation. Amino acids with low spatial variance occupy essentially the same relative position in all family members. This library is useful for building models, threading, and exploratory analysis. It is also a useful mechanism for summarizing variability in NMR structures.
Assembly Converter Map (liftover) your data's coordinates to the current assembly
BioGPS biogps.org BioGPS is a gene portal built with two guiding principles in mind - customizability and extensibility.
CATH Protein Structure Classification database
CiteAb citeab.com CiteAb’s antibody and biochemical search engine provides a simple way for researchers to find reagents that work.
Data Slicer Get a subset of data from a BAM or VCF file
Database of Interacting Proteins Univ. of California
Interact An Object Oriented Database for Protein-Protein Interactions.
DisProt Database of experimental evidences of disorder in proteins (Indiana University School of MedicineTemple UniversityUniversity of Padua)
ExPASy Molecular Biology Server This is the ExPASy proteomics server of the Swiss Institute of Bioinformatics (SIB). This server is dedicated to the analysis of protein sequences and structures as well as 2-D PAGE.
File Chameleon Convert Ensembl files for use with other analysis tools
guidetopharmacology.org This website is intended to become a “one-stop shop” portal to pharmacological information. The searchable database provides quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. It aims to offer accurate information on the basic science underlying drug action.
ID History Converter Convert a set of Ensembl IDs from a previous release into their current equivalents
InterPro InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.
Linkage Disequilibrium Calculator Calculate LD between variants using genotypes from a selected population
locate.imb.uq.edu.au LOCATE is a curated database that houses data describing the membrane organization and subcellular localization of proteins from the RIKEN FANTOM4 mouse and human protein sequence set.
mips.helmholtz-muenchen.de/corum Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. The CORUM database is a collection of experimentally verified mammalian protein complexes.
MobiDB Database of intrinsic protein disorder annotation (University of Padua)
ModBase Database of comparative protein structure models (Sali Lab, UCSF)
NCBI Protein sequence and knowledgebase (National Center for Biotechnology Information)
neXtProt A human protein-centric knowledge resource
PaxDB pax-db.org PaxDB is a comprehensive absolute protein abundance database, which contains whole genome protein abundance information across organisms and tissues.
Pfam Protein families database of alignments and HMMs (Sanger Institute)
PIR – Protein Information Resource The Protein Information Resource (PIR), in collaboration with the Munich Information Center for Protein Sequences(MIPS) and the Japanese International Protein Sequence Database (JIPID) maintains the PIR-International Protein Sequence Database – a comprehensive, annotated, and non-redundant set of protein sequence databases in which entries are classified into family groups and alignments of each group are available.
PIR-NREF The PIR-NREF is a Non-redundant REFerence protein database designed to provide a timely and comprehensive collection of all protein sequence data, keeping pace with the genome sequencing projects and containing source attribution and minimal redundancy.
PMD The Protein Mutant Database (PMD) covers natural as well as artificial mutants, including random and site-directed ones, for all proteins except members of the globin and immunoglobulin families. The PMD is based on literature, not on proteins. That is, each entry in the database corresponds to one article which may describe one, several or a number of protein mutants.
PRINTS A compendium of protein fingerprints from (Manchester University)
ProDom The Protein Domain database.
PROSITE PROSITE is a database of protein families and domains. It consists of biologically significant sites, patterns and profiles that help to reliably identify to which known protein family (if any) a new sequence belongs.
Protein Data Bank Worldwide repository for the processing and distribution of 3-D biological macromolecular structure data.  
Protein Data Bank (PDB) Protein database
Protein Databases Proteins, also known as the essential building blocks of a human body are a vital part of living organisms. Studies regarding the structure and...
Protein Information Resource Georgetown University Medical Center [GUMC])
Retrieve/ID mapping Batch search with UniProt IDs or convert them to another type of database ID (or vice versa)
Structural Classification of Proteins (SCOP) Structural classification
Swiss-model Server and repository for protein structure models
Swiss-Prot Protein knowledgebase (Swiss Institute of Bioinformatics)
Text Search Search by the name of protein
thebiogrid.org BioGRID is an interaction repository with data compiled through comprehensive curation efforts. The index searches publications for protein and genetic interactions, chemical associations and post translational modifications from major model organism species.
UniProt uniprot.org The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.
unihi.org Users can enter gene or protein identifiers from different organisms to obtain physical and regulatory interaction partners in the human interactome.
Uniprot UniProt Knowledgebase
UniprotKB UniProt Knowledgebase
UnifRef Provides clustered sets of sequences
UniParc A comprehensive and non-redundant database of publicly available protein sequences
Variant Effect Predictor Analyse your own variants and predict the functional consequences of known and unknown variants via our Variant Effect Predictor (VEP) tool
Variant Recoder Translate a variant identifier, HGVS notation or genomic SPDI notation to all possible variant IDs, HGVS, VCF format and genomic SPDI
VCF to PED converter Parse a vcf file to create a linkage pedigree file (ped) and a marker information file, which together may be loaded into ld visualization tools like Haploview
wwpdb.org Since 1971, the Protein Data Bank archive (PDB) has served as the single repository of information about the 3D structures of proteins, nucleic acids, and complex assemblies.

 

 

PROTEIN ATLAS

 

Human protein atlas A public database with expression profiles of human protein coding genes both on mRNA and protein level in tissues, cells, subcellular compartments, and cancer tumors.
proteinatlas.org The Human Protein Atlas aims to map all the human proteins in cells, tissues and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology.
Human Protein Atlas: aims at mapping all the human proteins in cells, tissues and organs Aims at mapping all the human proteins in cells, tissues and organs

 

PROTEIN CRYSTALLIZATION

Crystal TB Crystal T.B. is a database containing information on Protein Crystallization Conditions, which was carefully selected by experts in this field. The database greatly helps researchers in setting conditions for protein crystallization, by comparing information found in the database, thus contributing to reducing the time to analyze protein structures.

 

PROTEIN DOMAINS

Protein Domains Proteomics is known as the study of protein structures and these structural units are distinguished as protein domains. The overall functional role of a...
CDD A Conserved Domain Database and Search Service.

   

PROTEIN-PROTEIN OR DNA INTERACTION

Cytoscape Protein-protein and Protein-DNA interactions
NDEx Protein-protein and Protein-DNA interactions
String Protein-protein interaction networks, functional enrichment analysis

 

PROTEIN SIMILARITY

Similarity Matrix of Proteins (SIMAP) Database of protein similarities computed using FASTA

 

PROTEOME

Proteomes Set of proteins thought to be expressed by an organism

 

PEPTIDE MOFITS

Minimotif Miner Database of short contiguous functional peptide motifs

 

POLYGLUTAMIN REPEATS

PolyQ Database of polyglutamine repeats in disease and non-disease associated proteins

 

PROTEIN SEQUENCES

MIPS Munich Information Centre for Proteins Sequences (Germany).

 

PROTEIN-PROTEIN INTERACTION

Interact An Object Oriented Database for Protein-Protein Interactions.

 

PROTEOMICS

Human Protein Atlas (HPA) A public database with expression profiles of human protein coding genes both on mRNA and protein level in tissues, cells, subcellular compartments, and cancer tumors.