Human protein atlas

Tissue-based map of the human proteome

 
PCK2
 
PAX8

This section of the Human Protein Atlas focus on the expression profiles in human tissues of genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using immunohistochemistry. All underlying images of immunohistochemistry stained normal tissues are available together with knowledge-based annotation of protein expression levels. The protein data covers 15323 genes (76%) for which there are available antibodies. The mRNA expression data is derived from deep sequencing of RNA (RNA-seq) from 256 different normal tissue types.

More information about the specific content and the generation and analysis of the data in the section can be found on the Methods Summary.

Learn about:

  • protein localization in tissues at a single-cell level
  • if a gene is enriched in a particular tissue (specificity)
  • which genes have a similar expression profile across tissues (expression cluster)

 

THE TISSUE AND ORGAN PROTEOMESi
Explore the proteomes of specific tissues and organs

The expression for all protein-coding genes in all major tissues and organs in the human body can be explored in this interactive database, including numerous catalogs of proteins expressed in a tissue-restricted manner.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
HUMAN SUBPROTEOMES
Explore the various proteomes

The various subproteomes can be explored in this interactive database including numerous catalogs of protein-coding genes with detailed information regarding expression and localization of the corresponding proteins.


The Tissue-
specific Proteome

The Housekeeping
Proteome

The Regulatory
Proteome

The Secretome and
Membrane Proteome

The Isoform Proteome

The Cancer Proteome

The Druggable Proteome

Source:  Tissue-based map of the human proteome