Normal Processes

Explore these collections of interactive signaling pathways, diagrams, research guides, relevant products, publications, and other resources organized by research area topic. The interactive pathways and diagrams have been created by CST scientists and outside experts to provide concise overviews of selected signaling pathways and cellular mechanisms. Protein nodes in each interactive diagram are linked to specific antibody product information, as well as protein-specific listings in the PhosphoSitePlus® database of post-translational modifications.

 

Adhesion/ECM/Cytoskeleton

·    Adhesion

·    Adhesion/ECM/Cytoskeleton

·    Adherens Junction Dynamics

·    Contribution of Extracellular Matrix to EMT

·    Contribution of Soluble Factors to EMT

·    Tumor Angiogenesis

·    Mechanisms of Fibrosis

·    Regulation of Actin Dynamics

·    Regulation of Microtubule Dynamics

Cell Cycle Regulation

·    Cell Cycle Regulation

·    DNA Damage Response

·    G2M/DNA Damage Checkpoint

·    G1/S Checkpoint

·    Senescence Signaling

Cell Death

·    Cell Death

·    Regulation of Apoptosis

·    Death Receptor Signaling

·    Mitochondrial Control of Apoptosis

·    Inhibition of Apoptosis

·    Necrotic Cell Death

·    Autophagy Signaling

·    Senescence Signaling

Cellular Metabolism

·    Autophagy Signaling

·    Insulin Receptor Signaling

·    Warburg Effect

·    Hypoxia Signaling

·    Glutamine Metabolism

·    mTOR Signaling

·    AMPK Signaling

·    Senescence Signaling

·    Mechanisms of Fibrosis

Developmental Biology Signaling

·    Developmental Biology Signaling

·    Wnt/β-Catenin Signaling

·    TGF-β Signaling

·    Hedgehog Signaling

·    Notch Signaling

·    Hippo Signaling

·    Angiogenesis

·    Pluripotency and Differentiation

Epigenetics

·    Epigenetics

·    DNA Methylation

·    Histone Methylation

·    Protein Acetylation

·    Crosstalk Between Post-translational Modifications

·    Writers & Erasers of Histones H2A, H2B, and H4

·    Epigenetic Writers and Erasers of Histone H3

·    ATP-dependent Chromatin Remodeling

·    Nuclear Receptors

GPCR, Calcium, cAMP

·    GPCR, Calcium, cAMP

·    Protein Kinase C Signaling

·    Phospholipase Signaling

·    G-Protein-Coupled Receptors Signaling to MAPK/Erk

Immunology/Inflammation

·    Immunology/Inflammation

·    Toll-Like Receptor Signaling

·    Jak/Stat: IL-6 Receptor Signaling

·    T Cell Receptor Signaling

·    NF-κB Signaling

·    Cell Intrinsic Innate Immunity Signaling

·    B Cell Receptor Signaling

·    Inflammasome Signaling

·    Human Immune Cell Marker Guide

·    Mouse Immune Cell Marker Guide

·    Checkpoint Signaling in the Tumor Microenvironment

·    Mechanisms of Fibrosis

·    CAR Signaling Networks

Kinase Signaling

·    Kinase Signaling

·    ErbB / HER Signaling

·    SAPK/JNK Signaling Cascades

·    MAPK/Erk in Growth and Differentiation

·    G-Protein-Coupled Receptors Signaling to MAPK/Erk

·    p38 MAPK Signaling

·    AMPK Signaling

·    mTOR Signaling

·    PI3K/Akt Signaling

·    Phosphoinositide (Lipid) Signaling Pathway

·    Protein Kinase C Signaling

·    Insulin Receptor Signaling

·    Regulation of eIF4E and p70 S6 Kinase

·    Jak/Stat: IL-6 Receptor Signaling

Mitochondria

·    Mitochondria 

Neuroscience

·    Neuroscience

·    G-Protein-Coupled Receptors Signaling to MAPK/Erk

·    TREM2 Signaling

·    Vesicle Trafficking Presynaptic Signaling

·    Alzheimer's Disease Signaling

·    Dopamine Signaling in Parkinson's Disease

·    Neuronal and Glial Cell Markers

·    Post-Synaptic Signaling

PI3K/AKT/MAPK Signaling

·    PI3K/AKT/MAPK Signaling

·    PI3K/Akt Signaling

·    Phosphoinositide (Lipid) Signaling Pathway

·    MAPK/Erk in Growth and Differentiation

·    p38 MAPK Signaling

·    G-Protein-Coupled Receptors Signaling to MAPK/Erk

Protein Synthesis

·    Protein Synthesis

Receptor Tyrosin Kinase

·    Receptor Tyrosine Kinase

RNA Regulation, Translational Control, and Protein Synthesis

·    RNA Reg/Translational Ctrl/Protein Synthesis

·    m6A RNA Regulatory Diagram

·    RNA Lifecycle

·    Regulation of eIF4E and p70 S6 Kinase

·    Regulation of eIF2

·    Translational Control

·    Stem Cell & Lineage Markers

Ubiquitin and Ubiquitin-Like Protein Resources

·    Ubiquitin and Ubiquitin-Like Protein Resources

·    Ubiquitin / Proteasome

Vesicle Trafficking

·    Vesicle Trafficking