TiGER is a database developed by the Bioinformatics Lab at Wilmer Eye Institute of Johns Hopkins University. The database contains tissue-specific gene expression profiles or expressed sequence tag (EST) data, cis-regulatory module (CRM) data, and combinatorial gene regulation data. Learn more about the database.
To download the raw data files, click here. To search the database, use the following three views:
Enter a RefSeq gene (e.g., NM_052964), a UniGene (e.g., Hs.2182) or a gene symbol (e.g., myod1):
Transcription Factor View
Enter a transcription factor name:
Select a tissue:
1. Liu, X., Yu, X., Zack, D.J., Zhu, H., Qian, J. (2008) TiGER: a database for tissue-specific gene expression and regulation. BMC Bioinformatics. 9:271.
2. Yu, X., Lin, J., Zack, D.J., Qian, J. (2007) Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors. BMC Bioinformatics. 8:437.
3. Yu, X., Lin, J., Zack, D.J., Qian, J. (2006) Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues. Nucleic Acids Res. 34, 4925–4936.
4. Yu, X., Lin, J., Masuda, T., Esumi, N., Zack, D.J., Qian, J. (2006) Genome-wide prediction and characterization of interactions between transcription factors in Saccharomyces cerevisiae. Nucleic Acids Res. 34, 917–927.
Contact: Jiang Qian (email@example.com)