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TENASCIN-C
Lack of influence on development, adulthood, life span, and fecundity
Lack of alteration in the regeneration of the sciatic nerve, after axotomy
Deposition of collagen one, fibulin-two, and nidogen during wound healing similar to wild-type
Diminished appearance of fibronectin in wounds
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Forsberg, 1996
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Skin wounds and severed nerves heal normally in mice lacking tenascin-C.
Proc. Natl. Acad. Sci. U.S.A. 93, 6594-6599 (1996)
[96270586]
METHODOLOGY
( FROM T-BASE)
((tenascin))
|
| Line Name | DNA Construct |
| 1. |
beta-1 (+/-) ES cel |
A 5' mouse beta-1 integrin cDNA probe was provided by R.O. Hynes (REG:97212) and used to isolate several overlapping cosmid clones from a mouse genomic library from 129/.... |
| 2. |
TN (+/-) |
A genomic DNA clone containing exon 2 of mouse tenascin (TN) (also known by the synonyms cytotactin, hexabrachion, J1 glycoprotein, myotendinous antigen, and glioma mese.... |
| 3. |
beta-1 (-/-) ES cel |
A 5' mouse beta-1 integrin cDNA probe was provided by R.O. Hynes (REG:97212) and used to isolate several overlapping cosmid clones from a mouse genomic library from 129/.... |
| 4. |
P(zero) (-/-) |
The XbaI-HindIII fragment from lambda phage MP(zero)G118 containing the first coding exon of the P(zero) gene was subcloned into pBluescript KS(+).... |
| 5. |
TGF-beta3 (exon 6) |
A replacement-type targeting vector was constructed in which exon 6 of the transforming growth factor, beta-3 (Tgfb3) gene was replaced with a neomycin-resistance gene d.... |
| 6. |
TN (-/-) |
A genomic DNA clone containing exon 2 of mouse tenascin (TN) (also known by the synonyms cytotactin, hexabrachion, J1 glycoprotein, myotendinous antigen, and glioma mese.... |
| 7. |
Mag (-/-) |
A genomic clone containing the entire Mag (myelin-associated glycoprotein) gene was isolated from a mouse C57BL/6J genomic library by hybridization with the rat 0.95b |
Database Links
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