TCR-alpha-beta

 Increase in splenic B cells
 Loss of thymic medullae

Philpott et al., 1992
Mombaerts et al., 1992


 Substantial enlargement of lymphoid organs (in TCR alpha) due to environmental antigens
 Increase in TCR gamma delta+ cell population

Viney, 1994
Lymphocyte proliferation in mice congenitally deficient in T-cell receptor alpha beta + cells.
Proc Natl Acad Sci U S A 91, 11948-11952 (1994) [95083618]
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METHODOLOGY ( FROM T-BASE)

Search Results: ( (tcr))

Line Name DNA Construct
1. TCR V beta 8.1 Construct description is pending.
2. V alpha 2.3 A lambda phage clone with a 9.2 kb BamHI insert containing rearranged TCR V alpha 2.3/J alpha TA39 sequences was isolated from a BamHI-digested, si....
3. TCR V beta 8.2 The source of functionally rearranged T cell receptor beta gene here is a cytotoxic T cell clone, called B6.2.16 (Citation G00-310-118), which lyses male but not female....


Database links: TCRA

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors

Database links: TCRB

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors