ApoA-I


	ApoA-I Normal tissue cholesterol levels and synthesis Reduced HLD and non HDL cholesterol (HDL-C) Minimal elevation of HDL-C in response to high fat cholesterol diet (large increase in control mice) Increased triglyceride and free cholesterol Reduced cholesterylester (CE) Decreased delivery of HLL CE to peripheral tissues and liver Absolute decrease in unidirectional transport of cholesterol from peripheral tissues to the liver No alteration in peripheral tissue HMG-CoA reductase activity 2.3 fold decreased liver cholesterol 7 alpha-hydroxylase mRNA Database link:

ApoA-I

Normal tissue cholesterol levels and synthesis
Reduced HLD and non HDL cholesterol (HDL-C)
Minimal elevation of HDL-C in response to high fat cholesterol diet (large increase in control mice)
Increased triglyceride and free cholesterol
Reduced cholesterylester (CE)
Decreased delivery of HLL CE to peripheral tissues and liver
Absolute decrease in unidirectional transport of cholesterol from peripheral tissues to the liver
No alteration in peripheral tissue HMG-CoA reductase activity
2.3 fold decreased liver cholesterol 7 alpha-hydroxylase mRNA

Database link: