FRONTIERS IN BIOSCIENCE;
WHOLE BLOOD, SERUM AND PLASMA CHEMISTRY:H-N



Table of Conents

 

TYPICAL REFERENCE INTERVALS

Haptoglobin

Serum

60-270 mg/dL

0.01

0.6-2.7 g/L

Hemoglobin

Serum or Plasma

Qualitative

Quantitative

Whole Blood

Female

Male

 

Negative

0.5-5.0 mg/dL

12.0-16.0 g/dL

13.5-18.0 g/dL

 

---

10

10

 

 

Negative

5-50 mg/L

120-160 g/L

135-180 g/L

a-Hydoxybutyrate dehydronase

Serum

140-350 U/mL

1

140-350 kU/L

17- Hydroxycorticosteroids

Plasma

Male

Female

After 24 USP

Units of ACTH

I.M.

 

7-19 Fg/dL

9-21 Fg/dL

 

35-55 Fg/dL

 

25.591

 

193-524 nmol/L

248-579 nmol/L

 

966-1517 nmol/L

Immunoglobulins:

IgG

IgA

IgM

IgD

IgE

Serum

 

800-1801 mg/dL

113-563 mg/dL

54-222 mg/dL

0.5-3.0 mg/dL

0.01-0.04 mg/dL

 

0.01

 

10

 

8.0-18.0 g/L

1.1-5.6 g/L

0.5-2.2 g/L

5.0-30.0 mg/L

0.1-0.4 mg/L

Insulin

Plasma

Bioassay

Radioumunoassay

 

11-240 FIU/mL

4-24 FIU/mL

 

7.175++

 

79-1722 pmol/L

29-172 pmol/L

Insulin tolerance (0.1 unit/kg)

Serum

Fasting

30 min

90 min

 

Glucoseof 70-110 mg/dL

Fall to 50% of fasting level

Fasting level

 

0.05551

0.01

 

Glucose of 3.9-6.1 mmol/L

Fall to 0.5 of fasting level

Fasting level

Iron, total

Serum

60-150 Fg/dL

0.1719

10.7-26.9 mmol/L

Iron-binding capacity

Serum

250-400 Fg/dL

0.1719

44.8-71.6mmol/L

Iron Saturation

Serum

20-55%

0.01

Fraction of total iron-biding capacity :

0.20-0.55

Isocitric dehydrogenase

Serum

50-240 units/mL at 25EC

(Wolfson-Williams Ashman units)

0.0166

0.83-4.18 U/L at 25EC

Ketone bodies

Serum

Nagative

---

Negative

17- Ketosteroids

Plasma

25-125 Fg/dL

34.67W

866-4334 nmol/L

Lactic acid (as lactate)

Whole Blood

Venous

Arterial

 

5-20 mg/dL

3-7 mg/dL

 

0.1110

 

0.6-2.2 mmo/L

0.3-0.8 mmol/L

Lactate Dehydrogenase (LD)

Serum

(lactate6pyruvate) 80-120 units at 30EC

pyruvate6lactate)185-640 units at 30EC

lactate6pyruvate) 100-190 U/L at 37EC

0.48

 

 

1

38-62 U/L at 30EC

90-310 U/L at 30EC

100-190 U/L at 37EC

Lactate dehydrogenase isoenzymes

LD1 (anode)

LD2

LD3

LD4

LD5 (cathode)

Serum

 

 

17-27%

27-37%

18-25%

3-8%

0-5%

 

 

0.01

 

 

Fraction of total LD

0.017-0.27

0.27-0.37

0.18-0.25

0.03 -0.08

0.00-0.05

Lactate Dehydrogenase (heat stable)

Serum

30-60% of total

0.01

Fraction of total LD: 0.30-060

Lactose tolerance

Serum

Serum glucose changes similar to glucose tolerance tests

---

Serum glucose changes similar to glucose tolerance test

Lead

Whole blood

<50 Fg/dL

0.04826

<2.41 mmol/L

Leucine aminopeptidase (LAP)

Serum

Male

Female

 

80-200 U/mL (Goldbarg-Rutenberg)

75-185 U/mL (Goldbarg-Rutenberg)

 

0.24

 

19.2-48.0 U/L

18.0-44.4 U/L

Lipase

Serum

0-1.5 U/mL (Cherry-Crandall)

14-280 mIU/mL

278

1

0-417 U/L

14-280 U/L

Lipids, total

Cholesterol

Triglycerides

Phospholipids

Fatty acids (free)

Phospholipid phosphorus

Serum

400-800 mg/dL

150-250 mg/dL

10-90 mg/dL

150-380 mg/dL

9.0-15.0 mmol/L

8.0-11.0 mg/dL

0.01

0.02586

0.01129**

0.01

1

0.3229

4.00-8.00 g/L

3.88-6.47 mmol/L

0.11-2.15 mmol/L

1.50-3.80 g/L

9.0-15.0 mmol/L

2.58-3.55 mmol/L

Lithium

therapeutic interval

Serum

Negative

0.5-1.4 mEq/L

---

1

Negative

0.5-1.4 mmol/L

Long-acting thyroid-stimulating hormone (LATS)

Serum

None detected

---

None detected

 

Luteinizing hormone(LH)

Serum

Male

Female

 

6-30 mIU/mL

Midcycle peak: 3 times baseline value

Premenopausal <30 mIU/mL

Postmenopausal>35 mIU/mL

 

1

 

6-30 IU/L

Midcycle peak: 3 times baseline value

Premenopausal <30 IU/L

Postmenopausal>35 IU/L

Macrogobulins, total

Serum

70-430 mg/dL

0.01

0.7-4.3 g/L

Methemoglobin

Whole Blood

<0.24 g/dL

<1% of total hemoglobin

10

0.01

<2.4 g/L

Fraction of total hemoglobin <0.01

Mucoprotien

Serum

80-200 mg/dL

0.01

0.8-2.0 g/L

Muramidase

Serum

4-13 mg/L

 

 

4-13 mg/L

Myoglobin

Serum

<90 Fg/L

 

 

<90 mg/L

Nonprotien nitrogen (NPN)

Serum or Plasma

Whole Blood

20-35 mg/dL

25-50 mg/dL

0.7139

14.3-25.0 mmol/L

17.8-35.7 mmol/L

5'- Nucleotidase

Serum

0-1.6 units at 37EC

1

0-1.6 units at 37EC