|
Name |
Other names |
Family |
M. W. |
Expression |
Functions |
|
CD1a CD1b CD1c CD1d |
Ig superfamily (IgSF) |
43-49 |
Cortical thymocytes, Langerhans cells, Dendritic cells, B cells (CD1c), Intestinal epithelium (CD1d) |
MHC class I-like molecule, associated with b2-microglobulin. May have specialised role in antigen presentation |
|
|
CD2 |
T11, LFA-2 |
IgSF |
45-58 |
T cells, thymocytes, NK cells |
Adhesion molecule, binding CD58 (LFA-3). Can activate T cells |
|
CD2R |
T11-3 |
IgSF |
45-58 |
Activated T cells |
activation-dependent conformational form of CD2 |
|
CD3 |
T3 |
IgSF (gde) z/h related to FcR g chain |
g:25-28 |
Thymocytes, T cells |
Associated with the T cell antigen receptor. Required for cell surface expression of and signal transduction by TCR. |
|
CD4 |
T4, L3T4 |
IgSF |
55 |
Thymocyte subsets, helper and inflammatory T cells (about two thirds of peripheral T cells), monocytes, macrophages |
Coreceptor for MHC class II molecules. Binds lck on cytoplasmic face of membrane. Receptor for HIV-I and HIV-2 gp120. |
|
CD5 |
T1, Ly1 |
Scavenger receptor |
67 |
Thymocytes, T cells, subset of B cells |
Binds to CD72 |
|
CD6 |
T12 |
Scavenger receptor |
100-130 |
Thymocytes, T cells, B cell CLL |
unknown. |
|
CD7 |
IgSF |
40 |
Pluripotential hematopoietic cells, thymocytes, T cells |
unknown. Marker for T cell ALL and pluripotential stem cell leukemias |
|
|
CD8 |
T8, Lyt2,3 |
IgSF |
a: 32-34 |
Thymocyte subsets, cytotoxic T cells (about one third of peripheral T cells) |
Coreceptor for MHC class I molecules. Binds lck on cytoplasmic face of membrane |
|
CD9 |
tetraspanning membrane protein |
22-27 |
Pre-B cells, eosinophils, basophils, platelets |
possible role in platelet aggregation and activation |
|
|
CD10 |
Neutral endopeptidase, Common Acute Lymphocytic Leukemia Antigen (CALLA) |
100 |
B and T cell precursors, bone marrow stromal cells |
zinc metalloproteinase, marker for pre B ALL |
|
|
CD11a |
LFA-1 |
180 |
lymphocytes, granulocytes, monocytes and macrophages |
aL subunit of integrin LFA-1 (associated with CD18) ; binds to CD54 (ICAM-1), ICAM-2 and ICAM-3 |
|
|
CD11b |
Mac-1 |
170 |
myeloid and natural killer cells |
aM subunit of integrin CR3 (associated with CD18) ; binds CD54, complement component iC3b and extracellular matrix proteins |
|
|
CD11c |
CR4, |
150 |
myeloid cells |
aX subunit of integrin CR4 (associated with CD18) ; binds fibrinogen |
|
|
CDw12 |
90-120 |
monocytes, granulocytes, platelets |
unknown |
||
|
CD13 |
amino peptidase N |
150-170 |
myelomonocytic cells |
zinc metalloproteinase |
|
|
CD14 |
53-55 |
myelomonocytic cells |
receptor for complex of LPS and LPS binding protein (LBP) |
||
|
CD15 & CD15S |
Lewsi-x (Lex) |
neutrophils, eosinophils, monocytes |
branched pentasaccharide, expressed on glycolipids and many cell surface glycoproteins; the sialylated form is a ligand for CD62E (ELAM) |
||
|
CD16 a & b |
FcgRIII |
IgSF |
50-80 |
neutrophils, NK cells, macrophages |
component of low affinity Fc receptor, FcgRIII, mediates phagocytosis and ADCC. |
|
CDw17 |
neutrophils, monocytes, platelets |
lactosyl ceramide, a cell surface glycosphingolipid |
|||
|
CD18 |
95 |
Leukocytes |
integrin b2 subunit, associates with CD11a,b and c. |
||
|
CD19 |
IgSF |
95 |
B cells |
forms complex with CD21 (CR2)and CD81 (TAPA-1); coreceptor for B cells |
|
|
CD20 |
tetraspanning membrane protein |
33-37 |
B cells |
possible role in regulating B cell activation |
|
|
CD21 |
CR2 |
complement control protein (CCP) superfamily |
145 |
mature B cells, FDC |
receptor for complement component C3d, EBV. With CD19 and CD81 forms coreceptor for B cells |
|
CD22 |
BL-CAM |
IgSF |
a: 130 |
mature B cells |
Adhesion of B cells to monocytes, T cells |
|
CD23 |
FceRII |
C-type lectin |
45 |
mature B cells, activated macrophages, eosinophils, follicular dendritic cells, platelets |
low affinity receptor for IgE, ligand for CD19:CD21:CD81 coreceptor |
|
CD24 |
possible human homologue of mouse Heat Stable Antigen (HSA) or J11d. |
35-45 |
B cells, granulocytes |
unknown |
|
|
CD25 |
Tac |
a:CCP b: cytokine receptor superfamily |
a:55 |
activated T cells, B cells, monocytes |
IL-2 receptor |
|
CD26 |
Dipeptidyl peptidase IV |
110 |
Activated B and T cells, macrophages |
protease. Recently implicated in HIV entry into cells. |
|
|
CD27 |
NGF receptor superfamily |
50-55 |
Medullary thymocytes, T cells |
unknown |
|
|
CD28 |
Tp44 |
IgSF |
44 |
T cell subsets, activated B cells |
Activation of naive T cells, receptor for costimulatory signal (signal 2) binds CD80 (B7-1) and B7-2 |
|
CD29 |
130 |
Leukocytes |
Integrin b1 subunit, associates with CD49a in VLA-1 integrin |
||
|
CD30 |
Ki-1 |
NGF receptor superfamily |
105-120 |
Activated B and T cells |
unknown |
|
CD31 |
PECAM-1 |
IgSF |
130-140 |
monocytes, platelets, granulocytes, B cells, endothelial cells |
Possibly an adhesion molecule |
|
CDw32 |
FcgRII |
IgSF |
40 |
Monocytes, granulocytes, B cells eosinophils |
low affinity Fc receptor for aggregated Ig/immune complexes |
|
CD33 |
IgSF |
67 |
myeloid progenitor cells, monocytes |
unknown |
|
|
CD34 |
105-120 |
hematopoietic precursors, capillary endothelium |
Ligand for CD62 (L-selectin) |
||
|
CD35 |
CR1 |
CCP superfamily |
250 |
Erythrocytes, B cells, monocytes, neutrophils, eosinophils, FDC |
Complement receptor 1, binds C3B and C4b, mediates phagocytosis |
|
CD36 |
platelet GPIV |
88 |
platelets, monocytes |
unknown |
|
|
CD37 |
tetraspanning membrane protein |
40-52 |
mature B cells, mature T cells, myeloid cells |
unknown |
|
|
CD38 |
45 |
early B and T cells, activated T cells, germinal centre B cells, plasma cells |
unknown |
||
|
CD39 |
78 |
activated B cells, activated NK cells, macrophages, dendritic cells |
unknown, may mediate adhesion of B cells |
||
|
CD40 |
NGF receptor superfamily |
50 |
B cells, monocytes, dendritic cells |
receptor for costimulatory signal for B cells, binds CD40 Ligand (T-BAM), |
|
|
CD41 |
125/22 dimer |
platelets, megakaryocytes |
aIIb integrin, associates with CD61 to form GPIIb, binds fibrinogen, fibronectin, von Willebrand factor and thrombospondin |
||
|
CD42a, b,c,d |
a: GPIX |
a: 23 |
platelets, megakaryocytes |
binds von Willebrand factor, thrombin; essential for platelet adhesion at sites of injury |
|
|
CD43 |
leukosialin, sialophorin |
115-135 (PMN) |
leukocytes, except resting B cells |
binds CD54 (ICAM-1) |
|
|
CD44 |
Hermes antigen, Pgp-1 |
80-95 |
leukocytes, erythrocytes |
binds hyaluronic acid, mediates adhesion of leukocytes |
|
|
CD45 |
Leukocyte common antigen (LCA), T200, B220 |
180-240 |
leukocytes |
tyrosine phosphatase, augments signalling through antigen receptor of B and T cells, multiple isoforms result from alternative splicing (see below) |
|
|
CD45RO |
180 |
T cell subsets, B cell subsets, monocytes, macrophages |
isoform of CD45 containing none of the A, B and C exons |
||
|
CD45RA |
205-220 |
B cells, T cell subsets (naive T cells) monocytes |
isoforms of CD45 containing the A exon |
||
|
CD45RB |
T200 |
190-220 |
T cell subsets, B cells, monocytes, macrophages, granulocytes |
isoforms of CD45 containing the B exon |
|
|
CD45RC |
Restricted T200 |
||||
|
CD46 |
MCP |
CCP superfamily |
56/66 (splice variants) |
hematopoietic and non-hematopoietic nucleated cells |
membrane cofactor protein, binds to C3b and C4b to permit their degradation by Factor I |
|
CD47 |
47-52 |
all cells |
unknown, associated with Rh blood group |
||
|
CD48 |
Blast-1 |
IgSF |
40-47 |
leukocytes |
unknown |
|
CD49a |
VLA-1 |
210 |
activated T cells, monocytes |
a1 integrin, associates with CD29, binds collagen, laminin |
|
|
CD49b |
VLA-2 |
165 |
B cells, monocyte, platelets |
a2 integrin, associates with CD29, binds collagen, laminin |
|
|
CD49c |
VLA-3 |
125 |
B cells |
a3 integrin, associates with CD29, bindslaminin, fibronectin |
|
|
CD49d |
VLA-4 |
150 |
B cells, thymocytes |
a4 integrin, associates with CD29, binds fibronectin, PeyerÕs Patch HEV, VCAM-1 |
|
|
CD49e |
VLA-5 |
135, 25 dimer |
memory T cells, monocytes, platelets |
a5 integrin, associates with CD29, binds fibronectin |
|
|
CD49f |
VLA-6 |
120, 25 dimer |
memory T cells, thymocytes, monocytes |
a6integrin, associates with CD29, binds laminin |
|
|
CD50 |
ICAM3 |
130 |
thymocytes, T cells, B cells,monocytes, granulocytes |
unknown |
|
|
CD51 |
vitronectin receptor |
125,24 dimer |
platelets, megakaryocytes |
av integrin, associates with CD61, binds vitronectin, von Willebrand factor, fibrinogen and thrombospondin |
|
|
CD52 |
CAMPATH-1 |
21-28 |
thymocytes, T cells, B cells (not plasma cells), monocytes, granulocytes |
unknown, target for antibodies used therapeutically to deplete T cells |
|
|
CD53 |
MRC OX44 |
tetraspanning membrane protein |
35-42 |
leukocytes |
unknown |
|
CD54 |
ICAM-1 |
IgSF |
85-110 |
hematopoietic and non-hematopoietic cells |
InterCellular Adhesion Molecule, (ICAM)-1 binds CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1) integrins, receptor for rhinovirus |
|
CD55 |
DAF |
CCP superfamily |
60-70 |
hematopoietic and non-hematopoietic cells |
Decay Accelerating Factor (DAF), binds C3b, disassembles C3/C5 convertase |
|
CD56 |
NKH-1 |
IgSF |
175-185 |
NK cells |
isoform of Neural Cell Adhesion Molecule (NCAM), adhesion molecule |
|
CD57 |
HNK-1, Leu-7 |
NK cells subsets of T cells, B cells and monocytes |
oligosaccharide, found on many cell surface glycoproteins |
||
|
CD58 |
LFA-3 |
IgSF |
55-70 |
hematopoietic and non-hematopoietic cells |
Leukocyte Function-associated Antigen-3 (LFA-3), binds CD2, adhesion molecule |
|
CD59 |
Protectin, Mac inhibitor |
19 |
hematopoietic and non-hematopoietic cells |
binds comlement components C8 and C9, blocks assembly of membrane attack complex |
|
|
CD60 |
T cell subsets, platelets, monocytes |
oligosaccharide present on gangliosides |
|||
|
CD61 |
105 |
platelets, megakaryocytes, macrophages |
integrin b3 subunit, associates with CD41 (GPIIb/IIIa) or CD51 (vitronectin receptor) |
||
|
CD62E |
ELAM-1, E-selectin |
C type lectin |
140 |
endothelium |
endothelium leukocyte adhesion molecule (ELAM), bindssialyl-Lewis x, mediates rolling interaction of neutrophils on endothelium |
|
CD62L |
LAM-1, L-selectin, LECAM-1 |
C type lectin |
150 |
B cells, T cells, monocytes, NK cells |
leukocyte adhesion molecule (LAM), binds CD34, GlyCAM, mediates rolling interactions with endothelium |
|
CD62P |
P-selectin, PADGEM |
C type lectin |
140 |
platelets, megakaryocytes, endothelium |
adhesion molecule, binds sialyl Lewis x, mediates interaction of platelets with neutrophils, monocytes and rolling interaction of neutrophils on endothelium |
|
CD63 |
tetraspanning membrane protein |
53 |
activated platelets, monocytes, macrophages |
unknown, is lysosomal membrane protein translocated to cell surface after activation |
|
|
CD64 |
FcgRI |
IgSF |
72 |
monocytes, macrophages |
hign affinity receptor for IgG |
|
CD65 |
myeloid cells |
oligosaccharide component of a ceramide dodecasaccharide |
|||
|
CD65s |
Ceramide dodecasaccharide 4c |
||||
|
CD66a |
biliary glycoprotein-1 (BGP-1) |
IgSF |
160-180 |
neutrophils |
unknown, member of carcinoembryonic antigen (CEA) family (see below) |
|
CD66b |
previously CD67 |
IgSF |
95-100 |
granulocytes |
unknown, member of carcinoembryonic antigen (CEA) family |
|
CD66c |
Nonspecific Crossreacting Antigen (NCA) |
IgSF |
90 |
neutrophils, colon carcinoma |
unknown, member of carcinoembryonic antigen (CEA) family |
|
CD66d |
IgSF |
30 |
neutrophils |
unknown, member of carcinoembryonic antigen (CEA) family |
|
|
CD66e |
CarcinoEmbryonic Antigen (CEA) |
IgSF |
180-200 |
adult colon epithelium, colon carcinoma |
unknown, member of carcinoembryonic antigen (CEA) family |
|
CD66f |
Pregnancy specific glycoprotein |
||||
|
CD68 |
macrosialin |
110 |
monocytes, macrophages, neutrophils, basophils, large lymphocytes |
unknown |
|
|
CD69 |
Activation Inducer Molecule (AIM) |
28, 32 homo-dimer |
activated B cells, activated T cells, activated macrophages, activated NK cells |
unknown, early activation antigen |
|
|
CD70 |
Ki-24 |
75,95,170 |
activated B cells, activated T cells, macrophages |
unknown |
|
|
CD71 |
T9 |
90-95 homo-dimer |
activated leukocytes |
transferrin receptor |
|
|
CD72 |
Lyb-2 |
C type lectin |
42 homo-dimer |
B cells |
unknown, ligand for CD5 |
|
CD73 |
69 |
B cell subsets, T cell subsets |
ecto-5Õ-nucleotidase, dephosphorylates nucleotides to allow nucleoside uptake |
||
|
CD74 |
Ii, Ig |
33,35,41,43 (alternate initiation and splicing) |
B cells, macrophages, monocytes, MHC class II positive cells |
MHC class II associated Invariant chain |
|
|
CDw75 |
mature B cells, T cell subsets |
unknown, possibly oligosaccharide, dependent on sialylation |
|||
|
CDw76 |
mature B cells, T cell subsets |
unknown, possibly oligosaccharide, dependent on sialylation |
|||
|
CD77 |
Gb3, Pk blood group |
germinal center B cells |
unknown, |
||
|
CDw78 |
Ba |
B cells |
unknown |
||
|
CD79a, CD79b |
Iga, Igb |
IgSF |
a: 32-33 |
B cells |
components of B cell antigen receptor analogous to CD3, required for cell surface expression and signal transduction |
|
CD80 |
B7 (now B7-1), BB1 |
IgSF |
60 |
B cell subset |
costimulator, ligand for CD28 and CTLA-4 |
|
CD81 |
Target of AntiProliferative Antibody (TAPA-1) |
tetraspanning membrane protein |
26 |
lymphocytes |
associates with CD19, CD21 to form B cell coreceptor |
|
CD82 |
R2 |
tetraspanning membrane protein |
50-53 |
leukocytes |
unknown |
|
CD83 |
HB15 |
43 |
Activated B cells, activated T cells, circulating dendritic cells (veil cells) |
||
|
CDw84 |
GR6 |
73 |
monocytes, platelets, circulating B cells |
||
|
CD85 |
GR4 |
120, 83 |
monocytes, circulating B cells |
||
|
CD86 |
FUN-1, GR65 |
80 |
monocytes, activated B cells |
||
|
CD87 |
UPA-R |
50-65 |
granulocytes, monocytes, macrophages, activated T cells |
Urokinase plasminogen activator receptor |
|
|
CD88 |
C5aR |
rhodopsin superfamily |
40 |
polymorphonuclear leukocytes, macrophages, mast cells |
Receptor for complement component C5a |
|
CD89 |
FcaR |
IgSF |
50-70 |
monocytes, macrophages, granulocytes, neutrophils, B cell subsets, T cell subsets |
IgA receptor |
|
CD90 |
Thy-1 |
IgSF |
18 |
CD34+ prothymocytes (human) thymocytes, T cells (mouse) |
unknown |
|
CD91 |
unknown |
600 |
monocytes |
a2 macroglobulin receptor |
|
|
CDw92 |
GR9 |
70 |
neutrophils, monocytes, platelets, endothelium |
unknown |
|
|
CD93 |
GR11 |
120 |
neutrophils, monocytes, endothelium |
unknown |
|
|
CD94 |
KP43 |
43 |
T cell subsets, NK cells |
unknown |
|
|
CD95 |
Apo-1, Fas |
NGF receptor superfamily |
43 |
wide variety of cell lines in vivodistribution uncertain |
binds TNF-like ligand, induces apoptosis |
|
CD96 |
T cell ACTivation Increased Late Expression (TACTILE) |
160 |
activated T cells |
Unknown |
|
|
CD97 |
GR1 |
74, 80, 90 |
activated cells |
unknown |
|
|
CD98 |
4F2 |
80, 40 |
T cells, B cells, NK cells, granulocytes, all human cell lines |
unknown |
|
|
CD99 |
MIC2, E2 |
32 |
Peripheral blood lymphocytes, thymocytes |
Unknown |
|
|
CD100 |
GR3 |
150 |
Broad expression on haematopoietic cells |
unknown |
|
|
CD101 |
BPC#4,BB27;BA27 |
140 |
Granulocytes, macrophages |
Unknown |
|
|
CD102 |
ICAM-2 |
IgSF |
55-65 |
Resting lymphocytes, monocytes, strongest on vascular endothelial cells |
binds CD11a/CD18 (LFA-1) but not CD11b/CD18 (Mac-1) |
|
CD103 |
HML-1, a6, aE integrin |
150,25 |
Intraepithelial lymphocytes, 2-6% of peripheral blood lymphocytes |
aE integrin |
|
|
CD104 |
b4, b4 integrin |
220 |
Epithelia, Schwann cells, some tumour cells |
b4 integrin |
|
|
CD105 |
Endoglin |
95, homo-dimer |
Endothelial cells, bone marrow cell subset, in vitro activated macrophages |
unknown, possibly ligand for an integrin |
|
|
CD106 |
VCAM-1 |
IgSF |
100,110 |
Endothelial cells |
Adhesion molecule, ligand for VLA-4 |
|
CD107a |
Lysosomal Associated Membrane Protein-1 (LAMP-1) |
110 |
Activated platelets |
Unknown, is lysosomal membrane protein translocated to the cell surface after activation |
|
|
CD107b |
LAMP-2 |
120 |
activated platelets |
Unknown, is lysosomal membrane protein translocated to the cell surface after activation |
|
|
CDw108 |
GR2 |
80 |
Activated T cells in spleen, some stromal cells |
Unknown |
|
|
CD109 |
Platelet activation factor, GR56 |
170/50 |
Activated T cells, platelets, endothelial cells |
Unknown |
|
|
CD114 |
G-CSF receptor |
||||
|
CD115 |
M-CSFR, c-fms |
IgSF |
150 |
monocytes, macrophages |
Macrophage Colony Stimulating Factor (M-CSF) receptor |
|
CD116 |
GM-CSFRa |
cytokine receptor superfamily |
70-85 |
monocytes, neutrophils,eosinophils, endothelium |
Granulocyte, Macrophage Colony Stimulating Factor (GM-CSF) receptor a chain |
|
CD117 |
c-kit |
IgSF tyrosine kinase |
145 |
hematopoietic progenitors |
Stem Cell Factor (SCF) receptor |
|
CD118 |
IFNa,bR |
Broad cellular expression |
Interferon a, b receptor |
||
|
CD119 |
IFNgR |
90-100 |
marophages, monocytes, B cells, endothelium |
Interferon g receptor |
|
|
CD120a |
TNFR-I |
NFG receptor superfamily |
50-60 |
hematopoietic and non-hematopoietic cells, highest on epithelial cells |
TNF receptor, binds both TNFa and TNFb |
|
CD120b |
TNFR-II |
NFG receptor superfamily |
75-85 |
hematopoietic and non-hematopoietic cells, highest on myeloid cells |
TNF receptor, binds both TNFa and TNFb |
|
CD121a |
IL-1R type I |
IgSF |
80 |
thymocytes ,T cells |
type I interleukin 1 receptor, binds IL-1a and IL-1b |
|
CDw121b |
IL-1R, ytpe II |
IgSF |
60-70 |
B cells, macrophages, monocytes |
type II interleukin 1 receptor, binds IL-1a and IL-1b |
|
CD122 |
IL-2Rb |
75 |
Natural killer cells, resting T cell subpopulation, some B cell lines |
IL-2 receptor b chain |
|
|
CDw123 |
IL-3R |
cytokine receptor superfamily fibronectin type III superfamily |
70 |
Bone marrow stem cells, granulocytes, monocytes, megakaryocytes |
IL-3 receptor a chain |
|
CD124 |
IL-4R |
cytokine receptor superfamily fibronectin type III superfamily |
130-150 |
Mature B and T cells, haematopoietic precursor cells |
IL-4 receptor |
|
CDw125 |
IL-5R |
cytokine receptor superfamily fibronectin type III superfamily |
55-60 |
Eosinophils, basophils |
IL-5 receptor |
|
CD126 |
IL-6R |
IgSF cytokine receptor superfamily fibronectin type III superfamily |
80 |
Activated B cells and plsama cells, weak on most leukocytes |
IL-6 receptor a subunit |
|
CD127 |
IL-7R |
fibronectin type III superfamily |
68-79, possibly forms homodimers |
Bone marrow lymphoid precursors, pro-B cells, mature T cells,monocytes |
IL-7 receptor |
|
CDw128 |
IL-8R |
rhodopsin superfamily |
58-67 |
Neutrophils, basophils, T cell subset |
IL-8 receptor |
|
CDw130 |
IL-6rb |
IgSF |
130 |
Activated B cells and plasma cells; weak on most leukocytes; endothelial cels |
IL-6 receptor b subunit |
|
CDw131 |
IL-3R common beta chain |
95-120 |
monocytes, granulocytes, eosinophils, B cells, |
B and T cell growth |
|
|
CD132 |
common gamma chain |
64 |
T and B cells, fibroblasts haematopoietic precursors |
B and T cell growth |
|
|
CD134 |
OX-40 |
48-50 |
activated T cells |
adhesion activated T cells;ligand for gp34 |
|
|
CD135 |
FLT3/FLK2 |
130-150 |
CD34 cells, carcinoma cells |
receptor tyrosine kinase |
|
|
CDw136 |
MSP-R |
180 |
receptor tyrosine kinase |
||
|
CDw137 |
4-1BB |
30 |
T cells |
co-stimulatory T cell activation |
|
|
CD138 |
syndecan-1 |
plasma cells; syndecan 1 |
ligand for collagen type 1 |
||
|
CD139 |
|||||
|
CD140a |
180 |
PDGFRa |
|||
|
CD140b |
180 |
PDGFRb |
|||
|
CD141 |
Thrombomodulin |
100 |
myeloid cells, endothelial cells, smooth muscle cells |
myeloid thrombin receptor; regulation of coagulation |
|
|
CD142 |
Tissue Factor |
45 |
monocytes, endothelial cells |
receptor for clotting factor VII, inhibits clotting |
|
|
CD143 |
Angiotensin converting enzyme (ACE) |
170 |
endothelial and epithelial cells |
peptidyl-peptidase, ACE |
|
|
CD144 |
VE-Cadherin |
135 |
endothelial cells |
adhesion molecule;role in cell-cell adhesion |
|
|
CDw145 |
endothelial cells |
||||
|
CD146 |
MUC18, S-endo |
113-118 |
endothelial cells, melanoma cells, follicular dendritic cell |
homing of activated T cells |
|
|
CD147 |
Neurothelin, basoglin |
endothelial cells, myeloid cells, lymphocytes |
|||
|
CD148 |
HPTP-eta, p260 |
||||
|
CDw149 |
MEM-133 |
||||
|
CDw150 |
SLAM(surface lymphocyte activation marker) |
75-95 |
T and B cells |
signalling molecule |
|
|
CD151 |
PETA-3 |
||||
|
CD152 |
CTLA-4 |
44 |
T cells |
neg. regul. for T cells co stimul;ligand CD80,86 |
|
|
CD153 |
CD30L |
40 |
T cells |
co-stimulatory for T cells; ligand for CD30 |
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CD154 |
CD40L, T-BAM |
TNF |
32-39 |
T cells |
co-stimulatory molecule; ligand for CD40 |
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CD155 |
Polio virus receptor (PVR) |
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CD156 |
ADAM8 |
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CD157 |
MO-5, BST-1 |
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CD158a |
p58.1 |
58/50 |
T cells |
inhibition of cytotox; class-I specific NK-receptor |
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CD158b |
p58.2 |
58/50 |
T cells |
inhibition of cytotox; class-I specific NK-receptor |
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CD158c |
p58.3 |
55-58 |
T cells |
activating molecule;member of Ig superfamily |
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CD161 |
NKRP-1A |
60 |
NK cells |
regulation of NK cell-mediated cytotoxicity |
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CD162 |
P-selectin glycoprotein ligand-1 (PSGL-1) |
240 |
monocytes, granulocytes, T cells, subset of B cells |
adhesion molecule;leucocyte rolling; ligand P-selectin |
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CD163 |
GHI/61, M130 |
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CD164 |
MGC-24 |
80 |
myeloid cells, T cells, epithelial cells, bone marrow stroma cells |
adhesion molecule haem progenitor cells to stroma |
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CD165 |
AD2, gp37, A108 |
37 |
T cells, NK cells, platelets, thymocytes, thymic epithelium |
adhesion molecule thymocytes/thymic epithelium |
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CD166 |
ALCAM |
100 |
T cells, NK cells, platelets, thymocytes, activated B and T cells, eosinophils, fibroblasts, endothelial cells, keratinocytes |
adhesion molecule; ligand for CD6 |