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MYCOPLASMAS AND HIV INFECTION: FROM EPIDEMIOLOGY TO THEIR INTERACTION
WITH IMMUNE CELLS
Catherine Brenner, Olivier Neyrolles, Alain Blanchard
Institut Pasteur, Unité d'Oncologie Virale, Département
SIDA et Rétrovirus, 28, rue du Dr. Roux, 75724 Paris Cedex
15, France
Received 07/05/96; Accepted 07/09/96; On-line 08/01/96
TABLE OF CONTENTS
- 1. Abstract
- 2. Introduction
- 3. In vitro synergy between HIV and mycoplasma cell killing
activity
- 4. Mycoplasma isolation from HIV-infected patients
- 5. Prevalence of mycoplasmas in HIV-infected patients
- 5.1. Immuno-histochemistry evidence of mycoplasmas in tissues
from AIDS patients
- 5.2. PCR-based detection of mycoplasmas
- 5.3. Seroprevalence of M. penetrans and M. fermentans
- 5.3.1. M. penetrans
- 5.3.2. M. fermentans
- 6. M. fermentans and M. penetrans cytopathogenicity
- 6.1. Cell invasion
- 6.2. Mycoplasma adherence to host cells
- 7. Mycoplasma interactions with the immune system
- 7.1. Immune cell activators
- 7.2. Antigenic surface variation and immune escape
- 7.3. Molecular mimicry
- 8. Perspective
- 9. Acknowledgments
- 10. References
- 11. Entire manuscript
Key words: mollicute/mycoplasma/Mycoplasma fermentans/Mycoplasma
penetrans/ AIDS/HIV/cofactor/immune response/epidemiology
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