[Frontiers in Bioscience 1, d189-205, August 15, 1996]
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CAVEAT LECTOR



HUMAN SPERM ACTIVATION DURING CAPACITATION AND ACROSOME REACTION: ROLE OF CALCIUM, PROTEIN PHOSPHORYLATION AND LIPID REMODELLING PATHWAYS.

Elisabetta Baldi, Michaela Luconi, Lorella Bonaccorsi, Csilla Krausz and Gianni Forti.

Dipartimento di Fisiopatologia Clinica, Unita' di Andrologia, Universita' di Firenze, viale Pieraccini 6, I-50139 Firenze, Italy.

Received 05/30/96; Accepted 07/30/96; On-line 08/15/96

TABLE OF CONTENTS

1. Abstract
2. Sperm capacitation: background
2.1 Modification in concentration of intracellular calcium and other ions during capacitation
2.2 Changes in membrane lipids and phospholipids during capacitation
2.3 Changes in protein phosphorylation and protein kinase activity during capacitation
2.3.1. Involvement of PKA in capacitation
2.3.2. Involvement of PKC in capacitation
2.3.3. Involvement of tyrosine phosphorylation in capacitation
3. Acrosome reaction (AR): background
3.1 Intracellular calcium during acrosome reaction
3.2 Phospholipases activation during acrosome reaction
3.3 Activation of protein kinases during acrosome reaction
4. Perspective
5. Acknowledgements
6. References
7. Entire manuscript