IR, RAS, ATV induced SASP

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Uniprot


Genes


Protein Name


IR (fibro)


RAS


ATV


IR (epi)


P04406


GAPDH


Glyceraldehyde-3-phosphate dehydrogenase


6.78


3.83


1.91


0.94


P14618


PKM


Pyruvate kinase PKM


5.73


3.98


1.50


1.27


O43399


TPD52L2


Tumor protein D54


5.86


3.01


2.18


0.69


Q99988


GDF15


Growth/differentiation factor 15


2.54


5.07


3.08


1.96


Q16555


DPYSL2


Dihydropyrimidinase-related protein 2


6.00


2.25


1.48


0.68


Q9Y490


TLN1


Talin-1


5.13


2.92


0.91


0.79


P17096


HMGA1


High mobility group protein HMG-I/HMG-Y


2.53


3.38


3.59


1.40


P78417


GSTO1


Glutathione S-transferase omega-1


2.09


3.92


3.25


0.64


O14950;P19105


MYL12B


Myosin regulatory light chain 12B


4.93


1.53


1.63


0.65


P60709;P63261


ACTB


Actin, cytoplasmic 1


4.11


2.86


1.05


0.88


O00151


PDLIM1


PDZ and LIM domain protein 1


4.27


1.89


1.97


0.88


P46940


IQGAP1


Ras GTPase-activating-like protein IQGAP1


3.41


2.98


1.75


1.20


O00299


CLIC1


Chloride intracellular channel protein 1


2.68


3.37


1.07


1.00


A5A3E0


POTEF


POTE ankyrin domain family member F


2.94


3.01


1.29


0.62


Q15149


PLEC


Plectin


2.81


2.23


2.35


0.64


P0DMV8;P0DMV9


HSPA1A;HSPA1B


Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1B


2.96


2.40


1.45


0.67


Q562R1


ACTBL2


Beta-actin-like protein 2


2.02


2.93


0.98


0.70



Reference: A proteomic atlas of senescence-associated secretomes for aging biomarker development
Nathan Basisty,et al, PLOS Biology, 2020

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