Genes that are up or downregulated by calorie restriction

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MGI Description


MGI Symbol


EntrezID


total


overexp.


underexp.


p_overexp.


ATP-binding cassette, sub-family G (WHITE), member 5 Gene


Abcg5


27409


30


9


0


3.56E-8


actin binding LIM protein family, member 3 Gene


Ablim3


319713


21


7


1


5.42E-7


ATP citrate lyase Gene


Acly


104112


60


2


8


5.49E-5


acyl-CoA thioesterase 12 Gene


Acot12


74156


32


6


0


1.31E-4


acyl-CoA thioesterase 4 Gene


Acot4


171282


30


7


0


7.78E-6


actin, gamma, cytoplasmic 1 Gene


Actg1


11465


55


1


7


2.15E-4


adenylate cyclase 1 Gene


Adcy1


432530


11


4


0


1.15E-4


alcohol dehydrogenase 1 (class I) Gene


Adh1


11522


42


12


0


3.50E-10


alanine-glyoxylate aminotransferase 2-like 1 Gene


Agxt2l1


71760


18


5


0


6.55E-5


aminolevulinic acid synthase 2, erythroid Gene


Alas2


11656


58


3


8


4.28E-5


aldehyde dehydrogenase family 1, subfamily A1 Gene


Aldh1a1


11668


56


9


2


1.05E-5


aldehyde dehydrogenase family 1, subfamily A7 Gene


Aldh1a7


26358


35


6


2


2.19E-4


angiopoietin-like 4 Gene


Angptl4


57875


37


9


2


2.64E-7


aquaporin 6 Gene


Aqp6


11831


23


6


2


1.77E-5


aquaporin 8 Gene


Aqp8


11833


34


1


6


9.56E-5


aryl hydrocarbon receptor nuclear translocator-like Gene


Arntl


11865


63


3


11


1.41E-7


arrestin domain containing 2 Gene


Arrdc2


70807


40


7


0


5.72E-5


cDNA sequence BC089597 Gene


BC089597


216454


13


4


0


2.38E-4


BCL2/adenovirus E1B interacting protein 3 Gene


Bnip3


1E+08


14


4


0


3.27E-4


complement component 4 binding protein Gene


C4bp


12269


20


0


5


6.40E-5


complement component 9 Gene


C9


12279


36


1


7


1.28E-5


carbonic anhydrase 3 Gene


Car3


12350


49


0


11


8.86E-9


cancer susceptibility candidate 5 Gene


Casc5


76464


11


1


4


7.14E-5


carbonyl reductase 1 Gene


Cbr1


12408


38


7


0


4.04E-5


CD163 antigen Gene


Cd163


93671


14


4


1


3.27E-4


CDC42 effector protein (Rho GTPase binding) 2 Gene


Cdc42ep2


104252


28


1


5


3.50E-4


claudin 1 Gene


Cldn1


12737


34


1


6


9.56E-5


Cobl-like 1 Gene


Cobll1


319876


28


8


0


3.17E-7


collagen, type XV, alpha 1 Gene


Col15a1


12819


32


1


7


5.58E-6


collagen, type III, alpha 1 Gene


Col3a1


12825


59


1


7


3.35E-4


catechol-O-methyltransferase 1 Gene


Comt1


12846


55


2


7


2.15E-4


carnitine palmitoyltransferase 1a, liver Gene


Cpt1a


12894


53


8


1


5.16E-5


cryptochrome 1 (photolyase-like) Gene


Cry1


12952


49


8


0


2.87E-5


crystallin, mu Gene


Crym


12971


15


4


0


4.37E-4


connective tissue growth factor Gene


Ctgf


14219


35


8


0


2.05E-6


chemokine (C-X-C motif) ligand 9 Gene


Cxcl9


17329


37


0


6


1.56E-4


cytochrome P450, family 2, subfamily b, polypeptide 13 Gene


Cyp2b13


13089


23


6


1


1.77E-5


cytochrome P450, family 2, subfamily e, polypeptide 1 Gene


Cyp2e1


13106


39


7


0


4.82E-5


cytochrome P450, family 2, subfamily f, polypeptide 2 Gene


Cyp2f2


13107


37


0


6


1.56E-4


cytochrome P450, family 2, subfamily j, polypeptide 5 Gene


Cyp2j5


13109


25


0


8


4.64E-8


cytochrome P450, family 2, subfamily j, polypeptide 6 Gene


Cyp2j6


13110


30


9


0


3.56E-8


cytochrome P450, family 4, subfamily a, polypeptide 14 Gene


Cyp4a14


13119


32


8


0


9.80E-7


cytochrome P450, family 7, subfamily a, polypeptide 1 Gene


Cyp7a1


13122


39


9


2


4.30E-7


DNA segment, human D4S114 Gene


D0H4S114


27528


60


0


7


3.72E-4


D site albumin promoter binding protein Gene


Dbp


13170


34


10


4


7.63E-9


2,4-dienoyl CoA reductase 1, mitochondrial Gene


Decr1


67460


37


6


0


3.01E-4


2-4-dienoyl-Coenzyme A reductase 2, peroxisomal Gene


Decr2


26378


24


6


0


2.30E-5


7-dehydrocholesterol reductase Gene


Dhcr7


13360


49


0


10


1.11E-7


deoxyribonuclease 1-like 2 Gene


Dnase1l2


1E+08


7


0


3


3.61E-4


dipeptidylpeptidase 9 Gene


Dpp9


224897


28


0


6


3.00E-5


dual specificity phosphatase 1 Gene


Dusp1


19252


36


6


0


2.57E-4


enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase Gene


Ehhadh


74147


39


10


0


3.30E-8


glutamyl aminopeptidase Gene


Enpep


13809


25


5


0


3.51E-4


erythrocyte protein band 4.1 Gene


Epb4.1


269587


61


8


1


1.44E-4


esterase 31 Gene


Es31


382053


25


1


7


9.14E-7


exostoses (multiple)-like 1 Gene


Extl1


56219


24


1


5


1.63E-4


fatty acid binding protein 5, epidermal Gene


Fabp5


16592


59


3


8


4.85E-5


family with sequence similarity 107, member A Gene


Fam107a


268709


22


8


0


3.73E-8


family with sequence similarity 195, member A Gene


Fam195a


68241


20


6


0


7.23E-6


FK506 binding protein 5 Gene


Fkbp5


14229


59


11


1


2.34E-7


flavin containing monooxygenase 3 Gene


Fmo3


14262


29


8


0


4.28E-7


frizzled homolog 1 (Drosophila) Gene


Fzd1


14362


38


6


2


3.50E-4


G0/G1 switch gene 2 Gene


G0s2


14373


33


3


7


6.95E-6


glucose-6-phosphate dehydrogenase X-linked Gene


G6pdx


14381


54


2


7


1.92E-4


glucokinase Gene


Gck


103988


41


1


8


2.98E-6


growth hormone receptor Gene


Ghr


14600


65


0


8


9.82E-5


predicted gene 13768


Gm13768


627525


7


0


3


3.61E-4


predicted gene 6957 Gene


Gm6957


629219


13


5


0


1.09E-5


predicted gene 7450


Gm7450


665017


7


0


3


3.61E-4


G protein-coupled receptor 146 Gene


Gpr146


80290


31


6


0


1.08E-4


general transcription factor II I repeat domain-containing 1 Gene


Gtf2ird1


57080


27


0


5


2.93E-4


glycogen synthase 2 Gene


Gys2


232493


27


6


0


4.75E-5


2-hydroxyacyl-CoA lyase 1 Gene


Hacl1


56794


27


6


0


4.75E-5


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 Gene


Herpud1


64209


45


9


2


1.57E-6


homeodomain interacting protein kinase 2 Gene


Hipk2


15258


36


0


6


1.33E-4


hydroxysteroid (17-beta) dehydrogenase 2 Gene


Hsd17b2


15486


46


7


5


1.44E-4


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Gene


Hsd3b2


15493


24


0


5


1.63E-4


heat shock protein 5 Gene


Hspa5


14828


69


0


9


2.27E-5


heat shock protein family, member 7 (cardiovascular) Gene


Hspb7


29818


30


1


5


4.89E-4


interferon, alpha-inducible protein 27 like 2A Gene


Ifi27l2a


76933


20


0


5


6.40E-5


interferon induced with helicase C domain 1 Gene


Ifih1


71586


33


0


6


8.03E-5


interferon-related developmental regulator 1 Gene


Ifrd1


15982


45


7


0


1.25E-4


insulin-like growth factor binding protein 2 Gene


Igfbp2


16008


40


7


1


5.72E-5


inhibin beta E Gene


Inhbe


16326


42


2


6


3.20E-4


indolethylamine N-methyltransferase Gene


Inmt


21743


33


10


4


5.51E-9


insulin induced gene 1 Gene


Insig1


231070


33


1


7


6.95E-6


interferon regulatory factor 7 Gene


Irf7


54123


30


1


6


4.56E-5


immunity-related GTPase family M member 1 Gene


Irgm1


15944


28


0


6


3.00E-5


insulin receptor substrate 2 Gene


Irs2


384783


29


7


1


6.10E-6


Kruppel-like factor 10 Gene


Klf10


21847


36


6


0


2.57E-4


Kruppel-like factor 15 Gene


Klf15


66277


32


9


0


6.68E-8


Kruppel-like factor 9 Gene


Klf9


70273


14


5


0


1.67E-5


Kruppel-like factor 9 Gene


Klf9


16601


51


9


0


4.70E-6


LPS-induced TN factor Gene


Litaf


56722


60


0


7


3.72E-4


similar to acyl-CoA thioesterase


LOC100044830


1E+08


15


4


0


4.37E-4


similar to Deltex3


LOC100045005


1E+08


7


0


3


3.61E-4


similar to apolipoprotein D


LOC100047583


1E+08


5


4


0


1.96E-6


similar to WAP four-disulfide core domain 2


LOC100048733


1E+08


7


0


3


3.61E-4


similar to Ornithine decarboxylase (ODC)


LOC677259


677259


7


0


3


3.61E-4


lipin 1 Gene


Lpin1


14245


29


6


1


7.30E-5


lymphocyte antigen 6 complex, locus E Gene


Ly6e


17069


62


2


7


4.56E-4


mitogen-activated protein kinase kinase kinase 6 Gene


Map3k6


53608


26


5


0


4.25E-4


methionine adenosyltransferase I, alpha Gene


Mat1a


11720


60


8


0


1.28E-4


matrix Gla protein Gene


Mgp


17313


48


7


1


1.89E-4


matrix metallopeptidase 15 Gene


Mmp15


17388


27


0


5


2.93E-4


metallothionein 1 Gene


Mt1


17748


61


12


2


3.54E-8


metallothionein 2 Gene


Mt2


17750


59


14


5


1.85E-10


major urinary protein 4 Gene


Mup4


17843


24


0


5


1.63E-4


N-acetyltransferase 8 (GCN5-related, putative) Gene


Nat8


68396


26


9


0


8.53E-9


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Gene


Nfkbia


18035


61


8


0


1.44E-4


niacin receptor 1 Gene


Niacr1


80885


13


4


0


2.38E-4


nuclear receptor subfamily 1, group D, member 1 Gene


Nr1d1


217166


34


3


6


9.56E-5


nuclear receptor subfamily 1, group I, member 3 Gene


Nr1i3


12355


40


9


0


5.43E-7


neurotrophin 3 Gene


Ntf3


18205


42


8


0


8.79E-6


netrin 3 Gene


Ntn3


18209


15


0


4


2.75E-4


protein disulfide isomerase associated 3 Gene


Pdia3


14827


62


0


7


4.56E-4


period homolog 1 (Drosophila) Gene


Per1


18626


38


6


1


3.50E-4


period homolog 2 (Drosophila) Gene


Per2


18627


44


12


1


6.38E-10


PHD finger protein 19 Gene


Phf19


74016


27


0


5


2.93E-4


pleckstrin homology-like domain, family A, member 1 Gene


Phlda1


21664


39


1


7


2.23E-5


proviral integration site 3 Gene


Pim3


223775


57


9


0


1.21E-5


phospholipase A2, group XIIA Gene


Pla2g12a


66350


39


6


1


4.04E-4


phosphatidylinositol-specific phospholipase C, X domain containing 3 Gene


Plcxd3


239318


14


4


0


3.27E-4


perilipin 4 Gene


Plin4


57435


15


4


0


4.37E-4


perilipin 5 Gene


Plin5


66968


17


5


1


4.83E-5


P450 (cytochrome) oxidoreductase Gene


Por


18984


61


13


0


3.41E-9


peroxisome proliferator activated receptor alpha Gene


Ppara


19013


40


8


1


5.99E-6


proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) Gene


Psmb8


16913


39


0


6


2.11E-4


protein tyrosine phosphatase, receptor type, J Gene


Ptprj


668629


14


1


4


2.05E-4


R3H domain containing 2 Gene


R3hdm2


71750


49


0


7


1.02E-4


retinol binding protein 7, cellular Gene


Rbp7


63954


26


5


3


4.25E-4


regulator of G-protein signaling 16 Gene


Rgs16


19734


27


6


2


4.75E-5


rhomboid domain containing 2 Gene


Rhbdd2


215160


51


7


0


2.79E-4


Rho-related BTB domain containing 1 Gene


Rhobtb1


69288


26


5


0


4.25E-4


regulatory solute carrier protein, family 1, member 1 Gene


Rsc1a1


69994


13


0


4


1.49E-4


sal-like 1 (Drosophila) Gene


Sall1


58198


25


5


0


3.51E-4


sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) Gene


Sc5d


235293


38


0


6


1.82E-4


selenocysteine lyase Gene


Scly


50880


31


1


6


5.54E-5


scratch homolog 1, zinc finger protein (Drosophila) Gene


Scrt1


170729


25


0


5


2.00E-4


serine dehydratase Gene


Sds


231691


25


8


0


1.18E-7


serine (or cysteine) peptidase inhibitor, clade H, member 1 Gene


Serpinh1


12406


63


4


8


7.83E-5


solute carrier family 10, member 2 Gene


Slc10a2


20494


39


0


6


2.11E-4


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 Gene


Slc25a25


227731


41


7


0


6.74E-5


solute carrier family 25, member 42 Gene


Slc25a42


73095


25


5


1


3.51E-4


solute carrier family 37 (glucose-6-phosphate transporter), member 4 Gene


Slc37a4


14385


35


8


0


2.05E-6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6 Gene


Slc6a6


21366


60


1


12


7.66E-9


SPARC related modular calcium binding 1 Gene


Smoc1


64075


55


7


0


4.48E-4


sterol regulatory element binding transcription factor 1 Gene


Srebf1


20787


60


1


10


8.13E-7


ST3 beta-galactoside alpha-2,3-sialyltransferase 5 Gene


St3gal5


20454


41


7


1


6.74E-5


SH3 and cysteine rich domain 3 Gene


Stac3


237611


15


0


4


2.75E-4


sulfotransferase family 1A, phenol-preferring, member 1 Gene


Sult1a1


20887


37


6


0


3.01E-4


sulfotransferase family, cytosolic, 1C, member 2 Gene


Sult1c2


69083


27


6


1


4.75E-5


sulfotransferase family 1D, member 1 Gene


Sult1d1


53315


45


9


3


1.57E-6


sulfotransferase family 3A, member 1 Gene


Sult3a1


57430


23


5


1


2.32E-4


Sad1 and UNC84 domain containing 2 Gene


Sun2


223697


34


6


1


1.86E-4


tensin like C1 domain-containing phosphatase Gene


Tenc1


209039


60


10


0


2.41E-6


transmembrane protein 132D Gene


Tmem132d


243274


4


0


3


4.34E-5


transmembrane protein 218 Gene


Tmem218


66279


21


6


0


9.91E-6


tumor necrosis factor (ligand) superfamily, member 10 Gene


Tnfsf10


22035


19


0


5


4.89E-5


transducer of ErbB-2.1 Gene


Tob1


22057


40


6


0


4.66E-4


transformation related protein 53 inducible protein 13 Gene


Trp53i13


216964


29


7


1


6.10E-6


TSC22 domain family, member 3 Gene


Tsc22d3


14605


26


6


0


3.77E-5


tubulin tyrosine ligase-like family, member 12 Gene


Ttll12


223723


21


0


5


8.25E-5


ubiquitin specific peptidase 2 Gene


Usp2


53376


60


11


0


2.79E-7


WEE 1 homolog 1 (S. pombe) Gene


Wee1


22390


37


8


2


3.22E-6


zinc finger and BTB domain containing 16 Gene


Zbtb16


235320


19


7


0


2.46E-7


zinc finger protein 354A Gene


Zfp354a


21408


54


7


0


4.00E-4


zinc finger protein 64 Gene


Zfp64


22722


34


1


8


6.52E-7


RIKEN cDNA 1110051M20 gene Gene


1110051M20Rik


228356


33


0


6


8.03E-5


RIKEN cDNA 1110054M08 gene


1110054M08Rik


68841


16


1


4


3.60E-4


RIKEN cDNA 2810051F02 gene


2810051F02Rik


72704


7


0


3


3.61E-4


RIKEN cDNA 2900086B20 gene


2900086B20Rik


73074


15


0


4


2.75E-4


4432414F05Rik RIKEN cDNA 4432414F05 gene


4432414F05Rik


77027


4


3


0


6.24E-5


4833417J20Rik RIKEN cDNA 4833417J20 gene


4833417J20Rik


74604


4


3


0


6.24E-5

Reference: HAGR
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