Anti-longevity genes in Mus Musculus

[raw]









































































































































































































































Name


Symbol


Entrez ID


Max average lifespan change


adenylate cyclase 5


Adcy5


224129


30%  Upregulatedd


Adrenergic receptor, alpha 1b


Adra1b


11548


11%  Downregulated


Angiotensin II receptor, type 1a


Agtr1a


11607


26%  Upregulatedd


thymoma viral proto-oncogene 1


Akt1


11651


12%  Upregulatedd


thymoma viral proto-oncogene 2


Akt2


11652


9%  Upregulatedd


Cyclin-dependent kinase inhibitor 1A


Cdkn1a


12575


Upregulatedd


demethyl-Q 7


Coq7


12850


30%  Upregulatedd


Cardiotrophin 1


Ctf1


13019


18%  Upregulatedd


diacylglycerol O-acyltransferase 1


Dgat1


13350


23%  Upregulatedd


Eukaryotic translation elongation factor 1 epsilon 1


Eef1e1


66143


50%  Downregulated


eukaryotic translation initiation factor 5A2


Eif5a2


208691


Downregulated


Epidermal growth factor receptor pathway substrate 8


Eps8


13860


37%  Upregulatedd


Growth hormone


Gh


14599


Downregulated


Growth hormone receptor


Ghr


14600


40%  Upregulatedd


growth hormone releasing hormone


Ghrh


14601


46%  Upregulatedd


Growth hormone releasing hormone receptor


Ghrhr


14602


20%  Upregulatedd


glia maturation factor beta


GMFB


2764


6%  Downregulated


Glutathione peroxidase 4


Gpx4


625249


7%  Upregulatedd


glutathione S-transferase, alpha 4


Gsta4


14860


13%  Upregulatedd


Huntingtin


Htt


15194


18%  Upregulatedd


Insulin-like growth factor 1 receptor


Igf1r


16001


40%  Upregulatedd


inhibitor of kappaB kinase beta


Ikbkb


16150


23%  Upregulatedd


Insulin receptor


Insr


16337


33%  Upregulatedd


insulin receptor substrate 1


Irs1


16367


18%  Upregulatedd


insulin receptor substrate 2


Irs2


384783


18%  Upregulatedd


Potassium voltage-gated channel, shaker-related subfamily, member 3


Kcna3


16491


22%  Upregulatedd


macrophage migration inhibitory factor


Mif


17319


16%  Upregulatedd


myostatin


Mstn


17700


15%  Upregulatedd


Mdm2, transformed 3T3 cell double minute p53 binding protein


Mtbp


105837


20%  Upregulatedd


mechanistic target of rapamycin (serine/threonine kinase)


Mtor


56717


20%  Upregulatedd


myelocytomatosis oncogene


Myc


17869


21%  Upregulatedd


Pregnancy-associated plasma protein A


Pappa


18491


30%  Upregulatedd


period circadian clock 2


Per2


18627


Upregulatedd


POU domain, class 1, transcription factor 1


Pou1f1


18736


40%  Upregulatedd


protein kinase, cAMP dependent regulatory, type II beta


Prkar2b


19088


14%  Upregulatedd


Prophet of Pit1, paired-like homeodomain transcription factor


Prop1


19127


Upregulatedd


ribosomal protein S6 kinase, polypeptide 1


Rps6kb1


72508


19%  Upregulatedd


serine (or cysteine) peptidase inhibitor, clade E, member 1


Serpine1


18787


Upregulatedd


SHC (Src homology 2 domain containing) transforming protein 1


Shc1


20416


30%  Upregulatedd


Solute carrier family 13 (sodium/sulfate symporters), member 1


Slc13a1


55961


25%  Upregulatedd


surfeit gene 1


Surf1


20930


20%  Upregulatedd


telomeric repeat binding factor 2


Terf2


21750


Downregulated


Transformation related protein 53 binding protein 1


Trp53bp1


27223


Upregulatedd


transient receptor potential cation channel, subfamily V, member 1


Trpv1


193034


16%  Upregulatedd


ubiquitin D


Ubd


24108


20%  Upregulatedd

Reference: HAGR
[/raw]