Anti-longevity genes in Drosophila Melanogaster

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Name


Symbol


Entrez ID


Max average lifespan change


5-hydroxytryptamine (serotonin) receptor 2A


5-HT2A


40575


90% 


Adenosylhomocysteinase like 1


AhcyL1


38342


13% 


Adenosylhomocysteinase like 2


AhcyL2


42043


21% 


Alpha Mannosidase I


alpha-Man-I


31957


39% 


ATP citrate lyase


ATPCL


36760


32% 


Baboon


babo


35900


16% 


Bmcp


Bmcp


39322



CG12317-PA


JhI-21


34624


32% 


CG17367 gene product from transcript CG17367-RC


Lnk


43130


33% 


CG17856 gene product from transcript CG17856-RA


CG17856


43369


18% 


CG18809 gene product from transcript CG18809-RA


CG18809


59170


19% 


CG2789


CG2789


33231


27% 


CG31196 gene product from transcript CG31196-RA


14-3-3epsilon


42186


49% 


CG33336-PA


p53


2768677


58% 


CG3810 gene product from transcript CG3810-RC


Edem1


31154


30% 


CG3962 gene product from transcript CG3962-RA


Keap1


42062


10% 


CG42358


CG42358


7354421



CG5389 gene product from transcript CG5389-RA


CG5389


39761


11% 


CG6824-PA


ovo


31429


50% 


CG7471-PA


Rpd3


38565


52% 


CG9172 gene product from transcript CG9172-RA


CG9172


32565


46% 


Chameau


chm


43928


24% 


Coenzyme Q biosynthesis protein 2


Coq2


40988


31% 


crooked legs


crol


34592


27% 


dawdle


daw


33474


35% 


diminutive


dm


31310


47% 


DNA polymerase Gamma


DNApol-gamma35


3772064


52% 


dunce


dnc


31309



Ecdysone receptor


EcR


35540


50% 


Enhancer of zeste


E(z)


39203


76% 


enigma


Egm


36242



escargot


esg


34903


21% 


extra sexcombs


esc


34595


59% 


Glycerol 3 phosphate dehydrogenase


Gpdh


33824


20% 


Glycogen phosphorylase


GlyP


33386


17% 


Glycogen synthase


GlyS


41823


10% 


Gustatory receptor 63a


Gr63a


38453


30% 


Hexokinase A


Hex-A


45875


10% 


Hexokinase C


Hex-C


44008



I’m not dead yet protein


Indy


40049


92% 


Insulin receptor substrate-1


chico


64880


48% 


Insulin-like 1 receptor


InR


42549


85% 


Insulin-related peptide


Ilp2


39150


47% 


Integrin linked kinase


Ilk


53573


63% 


Juvenile hormone esterase binding protein 29 (DmP29)


CG3776


37996


43% 


krasavietz


kra


40680


25% 


kugelkern


kuk


42063



l(3)neo18


l(3)neo18


46260


24% 


Lamin B receptor


LBR


37482



lethal (3) DTS3


l(3)DTS3


249462


42% 


locomotion defects


loco


42672



mir-184 stem loop


mir-184


12798434



mir-277 stem loop


mir-277


12798086


70% 


mushroom-body expressed


mub


40436


21% 


myospheroid


mys


44885


44% 


NADH:ubiquinone reductase 75kD subunit precursor


ND75


31762


15% 


neuropeptide F


NPF


42018


25% 


Odorant receptor co-receptor


Orco


40650


56% 


pickpocket 23


ppk23


32731


4% 


pickpocket 28


ppk28


32671


44% 


puckered


puc


40958



retinal degeneration A


rdgA


31826


44% 


Ribose-5-phosphate isomerase


Rpi


246599


38% 


RNA polymerase III subunit C53


RpIIIC53


40002


11% 


RPS6-p70-protein kinase


S6k


38654



Smad on X


Smox


31738


10% 


snazarus (sorting nexin lazarus)


snz


31704


85% 


Stunted


sun


44046



surfeit gene 1


Surf1


44498



Target of rapamycin


Tor


47396



Tequila


teq


39048


31% 


Tetraspanin 42Ef


Tsp42Ef


35615


18% 


trachealess


trh


38065


90% 

Reference: HAGR
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