Anti-longevity genes in Caenorhabditis Elegans

Name

Symbol

Entrez ID

Max average lifespan change

Amino Acid Transporter

aat-8

185079

30% 

ABC transporter, eXtended

abcx-1

183860

16%  Upregulatedd

Acyl CoA DeHydrogenase

acdh-13

177654

57%  Upregulatedd

Abnormal acetylcholinesterase

ace-1

181706

8%  Upregulatedd

Acyltransferase-like

acl-11

185044

Upregulatedd

Inactive angiotensin-converting enzyme-related protein

acn-1

180780

21%  Upregulatedd

ACOnitase

aco-2

176121

20%  Upregulatedd

fatty Acid CoA Synthetase family

acs-4

176005

6%  Upregulatedd

fatty Acid CoA Synthetase family

acs-5

176785

52%  Upregulatedd

hypothetical protein

acs-7

174472

20%  Upregulatedd

Ageing alteration AGE-1, abnormal DAuer Formation DAF-23

age-1

174762

1000%  Upregulatedd

AKT kinase family

akt-1

179424

Upregulatedd

AMmonium Transporter homolog

amt-2

186047

20%  Upregulatedd

Adenine Nucleotide Translocator

ant-1.1

176773

40%  Upregulatedd

Protein APS-1

aps-1

178989

8%  Upregulatedd

daPtin, Small chain (clathrin associated complex)

aps-3

171691

40%  Upregulatedd

ADP-Ribosylation Factor related

arf-1.1

191609

10%  Upregulatedd

Arrestin family

arr-1

180446

35%  Upregulatedd

Protein ASB-1

asb-1

175605

6%  Upregulatedd

ATP Synthase B homolog

asb-2

180718

Upregulatedd

ATP Synthase G homolog

asg-1

172673

Upregulatedd

ATP synthase subunit

asg-2

180956

Upregulatedd

ASH histone methyltransferase complex subunit (Drosophila absent, small or homeotic discs)

ash-2

174838

30%  Upregulatedd

Acid SphingoMyelinase

asm-3

176879

50%  Upregulatedd

ATPase family AAA domain-containing protein 3

atad-3

174590

29%  Upregulatedd

ATF (cAMP-dependent transcription factor) family

atf-6

181405

18%  Upregulatedd

Activating Transcription Factor associated with Stress

atfs-1

179922

26%  Downregulated

ATP synthase F1 subunit gamma

atp-2

175716

43%  Upregulatedd

ATP synthase subunit

atp-3

172195

21%  Upregulatedd

ATP synthase subunit

atp-4

179025

Upregulatedd

ATP synthase subunit

atp-5

179541

Upregulatedd

Protein ATX-3

atx-3

180049

50%  Upregulatedd

hypothetical protein

B0024.4

179432

15%  Upregulatedd

Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial

B0250.5

180344

10%  Upregulatedd

Protein B0303.2

B0303.2

176217

5%  Upregulatedd

Protein B0491.5

B0491.5

174734

60%  Upregulatedd

Protein B0511.6

B0511.6

172954

50%  Upregulatedd

Protein B0546.3

B0546.3

182030

27%  Upregulatedd

Branched-chain-amino-acid aminotransferase, cytosolic

bcat-1

181423

25%  Upregulatedd

Yeast BUB homolog

bub-3

175018

6%  Upregulatedd

hypothetical protein

C03H5.3

173427

20%  Upregulatedd

transposase

C09B7.2

182438

Upregulatedd

Protein C18E9.10

C18E9.10

174427

Upregulatedd

Protein C18E9.4

C18E9.4

174428

60%  Upregulatedd

Protein C26B2.2

C26B2.2

182926

Upregulatedd

Protein C27B7.7

C27B7.7

177708

Upregulatedd

Protein C28H8.11

C28H8.11

175836

15%  Upregulatedd

Protein C33F10.12

C33F10.12

183168

Upregulatedd

Lon protease homolog, mitochondrial

C34B2.6

172966

11%  Upregulatedd

Protein C35A11.3

C35A11.3

183228

Upregulatedd

Protein C36H8.1

C36H8.1

178230

Upregulatedd

Protein C42C1.3

C42C1.3

183399

60%  Upregulatedd

Protein C46G7.2

C46G7.2

177367

44%  Upregulatedd

Protein C47D12.2

C47D12.2

174789

6%  Upregulatedd

Protein C47E12.2

C47E12.2

177858

36%  Upregulatedd

Protein C48E7.2

C48E7.2

172321

26%  Upregulatedd

Protein C56G2.1

C56G2.1

175898

20%  Upregulatedd

C. Briggsae CBR-DAF-2 protein

Cbr-daf-2

8582838

40%  Upregulatedd

Cytochrome C Heme-Lyase

cchl-1

174713

50%  Upregulatedd

Cytochrome C Oxidase

cco-1

172832

80%  Upregulatedd

Cytochrome C Oxidase

cco-2

176707

60%  Upregulatedd

T-complex protein 1 subunit alpha

cct-1

174318

10%  Upregulatedd

Chaperonin Containing TCP-1

cct-4

174330

28%  Upregulatedd

Chaperonin Containing TCP-1

cct-6

175819

20%  Upregulatedd

Chaperonin Containing TCP-1

cct-8

176928

16%  Upregulatedd

Cell Division Cycle related

cdc-25.1

172353

Upregulatedd

Cell Division Cycle related

cdc-25.3

176260

40%  Upregulatedd

Protein CDC-48.1

cdc-48.1

174624

50%  Upregulatedd

Protein CEC-3

cec-3

174265

Upregulatedd

Cell Death abnormality

ced-3

178272

19%  Upregulatedd

Protein CEH-18

ceh-18

180671

Upregulatedd

hypothetical protein

CELE_C17H1.7

182749

15%  Upregulatedd

hypothetical protein

CELE_C25H3.9

173963

30%  Upregulatedd

hypothetical protein

CELE_C31B8.4

183078

13%  Upregulatedd

Protein C32H11.1

CELE_C32H11.1

183126

Upregulatedd

Protein C32H11.5

CELE_C32H11.5

183129

Upregulatedd

Protein C33A12.1

CELE_C33A12.1

177786

50%  Upregulatedd

Protein D1054.14

CELE_D1054.14

179499

36%  Upregulatedd

Dehydrogenase

CELE_D1054.8

183917

Upregulatedd

Protein E03H12.5

CELE_E03H12.5

177262

Upregulatedd

hypothetical protein

CELE_F11A3.2

179331

14%  Upregulatedd

hypothetical protein

CELE_F23F12.3

175926

15%  Upregulatedd

Protein F29C4.2

CELE_F29C4.2

176828

100%  Upregulatedd

Protein F49F1.12

CELE_F49F1.12

186068

Upregulatedd

Protein F53F4.11

CELE_F53F4.11

179849

27%  Upregulatedd

hypothetical protein

CELE_F53H1.3

176945

30%  Upregulatedd

Protein F56D5.5

CELE_F56D5.5

177772

20%  Upregulatedd

Protein F59C6.5

CELE_F59C6.5

172933

70%  Upregulatedd

Protein R02D3.3

CELE_R02D3.3

176838

13%  Upregulatedd

hypothetical protein

CELE_R03D7.4

174683

13%  Upregulatedd

Protein R05A10.5

CELE_R05A10.5

187596

Upregulatedd

Protein T06G6.4

CELE_T06G6.4

173140

Upregulatedd

Protein W09C5.8

CELE_W09C5.8

173237

100%  Upregulatedd

hypothetical protein

CELE_Y39B6A.3

180262

50%  Upregulatedd

Protein Y39F10C.1

CELE_Y39F10C.1

189761

Upregulatedd

Protein Y39G10AR.8

CELE_Y39G10AR.8

171792

24%  Upregulatedd

hypothetical protein

CELE_Y41C4A.11

189814

13%  Upregulatedd

Protein Y43F8B.12

CELE_Y43F8B.12

189875

Upregulatedd

hypothetical protein

CELE_Y46G5A.20

174915

15%  Upregulatedd

hypothetical protein

CELE_Y47H9C.1

173061

10%  Upregulatedd

Protein Y53F4B.23

CELE_Y53F4B.23

190220

Upregulatedd

Protein Y54E10BR.4

CELE_Y54E10BR.4

171874

15%  Upregulatedd

Protein Y69A2AR.19

CELE_Y69A2AR.19

177036

19%  Upregulatedd

Protein Y75B8A.13

CELE_Y75B8A.13

176648

Upregulatedd

Protein Y75B8A.33

CELE_Y75B8A.33

190713

Upregulatedd

C. Elegans P-53-like protein

cep-1

172616

33%  Upregulatedd

Ceramide glucosyltransferase 2

cgt-2

181790

40%  Upregulatedd

Abnormal chemotaxis

che-11

179666

40%  Upregulatedd

Abnormal chemotaxis

che-13

186607

40%  Upregulatedd

Abnormal chemotaxis

che-2

180401

50%  Upregulatedd

Abnormal chemotaxis

che-3

172593

100%  Upregulatedd

CHeckpoint Kinase

chk-1

3565921

25%  Upregulatedd

Protein CHN-1

chn-1

172303

7%  Upregulatedd

Caffeine Induced Death (S. pombe Cid) homolog

cid-1

175707

Upregulatedd

Caenorhabditis KU

cku-70

176546

Upregulatedd

C-type LECtin

clec-186

178238

Upregulatedd

C-type LECtin

clec-227

184216

Upregulatedd

Coenzyme Q7 homolog

clk-1

175729

Upregulated and Downregulated

CalciNeurin B

cnb-1

179572

30%  Upregulatedd

Collagen

col-93

259335

Upregulatedd

CalPoNin

cpn-3

171986

10%  Upregulatedd

Protein CPNA-3

cpna-3

3565393

Upregulatedd

Cell-death-Related Nuclease

crn-5

174634

41%  Upregulatedd

hypothetical protein

crtc-1

259368

53%  Upregulatedd

Caspase

csp-2

177391

Upregulatedd

C-terminal-binding protein 1

ctbp-1

180853

20%  Upregulatedd

CUTiclin-Like

cutl-28

176895

28%  Upregulatedd

Coexpressed With Polycystins

cwp-4

178894

Upregulatedd

Cytochrome c1

cyc-1

172582

87%  Upregulatedd

CYtochrome C

cyc-2.1

177243

80%  Upregulatedd

cyk-3

cyk-3

175853

15%  Upregulatedd

CYtochrome P450 family

cyp-13B1

181462

20%  Upregulatedd

CYtochrome P450 family

cyp-33E2

185653

18%  Upregulatedd

Alpha-1,2-mannosidase I

D2030.1

172510

9%  Upregulatedd

Protein D2030.4

D2030.4

172513

40%  Upregulatedd

Protein D2085.3

D2085.3

174387

Upregulatedd

Abnormal dauer Formation

daf-1

176829

46%  Upregulatedd

Abnormal dauer Formation

daf-10

184883

60%  Upregulatedd

Abnormal dauer Formation

daf-12

181263

Upregulatedd

Abnormal dauer Formation

daf-14

177908

44%  Upregulatedd

Abnormal dauer Formation

daf-15

177770

Upregulatedd

Abnormal dauer Formation

daf-19

174577

50%  Upregulatedd

Abnormal dauer Formation DAF-2, fork head-related transcription factor (daf-2)

daf-2

175410

200%  Upregulatedd

Abnormal dauer Formation

daf-3

180431

16%  Downregulated

Abnormal dauer Formation

daf-4

175781

120%  Upregulatedd

Abnormal dauer Formation

daf-6

181584

50%  Upregulatedd

Abnormal dauer Formation

daf-7

175237

50%  Upregulatedd

Abnormal dauer Formation

daf-8

187612

31%  Upregulatedd

Abnormal dauer Formation

daf-9

180889

74%  Upregulatedd

DAF-16/FOXO Controlled, germline Tumor affecting

dct-12

190351

14%  Upregulatedd

DAF-16/FOXO Controlled, germline Tumor affecting

dct-13

178476

23%  Upregulatedd

DAF-16/FOXO Controlled, germline Tumor affecting

dct-14

189684

19%  Upregulatedd

DAF-16/FOXO Controlled, germline Tumor affecting

dct-15

189289

10%  Upregulatedd

Daf-16-Dependent Longevity (WT but not daf-16 lifespan increased)

ddl-1

173954

24%  Upregulatedd

Daf-16-Dependent Longevity (WT but not daf-16 lifespan increased)

ddl-2

190025

24%  Upregulatedd

Daf-16-Dependent Longevity (WT but not daf-16 lifespan increased)

ddl-3

175087

Upregulatedd

DEgeneration Suppressor

des-2

179574

60%  Upregulatedd

Putative diacylglycerol kinase K06A1.6

dgk-5

174068

11%  Upregulatedd

human DICE1 (Deleted In Cancer) homolog

dic-1

177676

22%  Upregulatedd

D Kinase Family

dkf-2

180121

40%  Upregulatedd

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

dlat-1

179945

10%  Upregulatedd

Protein DLD-1

dld-1

178387

61%  Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-17

187266

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-18

183813

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-19

178564

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-20

182037

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-21

183134

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-22

178247

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-23

186056

Upregulatedd

Downstream Of DAF-16 (regulated by DAF-16)

dod-24

178245

Upregulatedd

DOT1 histone methyltransferase

dot-1.1

171797

15%  Upregulatedd

Dietary Restriction Like

drl-1

3565236

60%  Upregulatedd

Protein DRR-1

drr-1

174994

Upregulatedd

Protein DRR-2

drr-2

259546

Upregulatedd

EATing: abnormal pharyngeal pumping

eat-1

 

30%  Upregulatedd

EATing: abnormal pharyngeal pumping

eat-18

13183021

60%  Upregulatedd

hypothetical protein

eat-18

24105308

14%  Upregulatedd

EATing: abnormal pharyngeal pumping EAT-2

eat-2

175072

Upregulatedd

EATing: abnormal pharyngeal pumping

eat-3

174476

10%  Upregulatedd

EATing: abnormal pharyngeal pumping

eat-6

179796

40%  Upregulatedd

Elongation factor 1-alpha

eef-1A.1

175975

18%  Upregulatedd

EGg Laying defective

egl-10

179707

Upregulatedd

Erythroid-Like Transcription factor family

egl-18

176992

Upregulatedd

EGg Laying defective

egl-3

179412

65%  Upregulatedd

EGg Laying defective

egl-30

171751

38%  Upregulatedd

EGg Laying defective

egl-45

176094

52%  Upregulatedd

EGg Laying defective

egl-8

178537

83%  Upregulatedd

EGg Laying defective

egl-9

179461

20%  Upregulatedd

Protein EIF-1

eif-1

266853

25%  Upregulatedd

Eukaryotic Initiation Factor

eif-3.B

175138

51%  Upregulatedd

Eukaryotic Initiation Factor

eif-3.F

174478

32%  Upregulatedd

Eukaryotic translation initiation factor 3 subunit K

eif-3.K

179779

40%  Upregulatedd

ELongin C

elc-1

190775

12%  Upregulatedd

fatty acid ELOngation

elo-1

177787

11%  Upregulatedd

fatty acid ELOngation

elo-2

178532

9%  Upregulatedd

Erythroid-Like Transcription factor family

elt-6

176993

34%  Upregulatedd

Protein EMB-27

emb-27

174314

10%  Upregulatedd

hypothetical protein

ent-5

184599

20%  Upregulatedd

Enhancer of PolyComb-like

epc-1

176679

20%  Upregulatedd

Endogenous-RNAi deficient arGOnaute

ergo-1

178602

19%  Upregulatedd

Ezrin/Radixin/Moesin

erm-1

172174

15%  Upregulatedd

Endoplasmic Reticulum Oxidase

ero-1

173325

32%  Upregulatedd

ETS class transcription factor

ets-4

180927

40%  Upregulatedd

EXOSome (multiexonuclease complex) component

exos-3

186604

12%  Upregulatedd

Phosphate carrier protein, mitochondrial

F01G4.6

178020

12%  Upregulatedd

Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

F02A9.4

176285

13%  Upregulatedd

Protein F08B4.7

F08B4.7

177674

21%  Upregulatedd

Protein F09F7.3

F09F7.3

175767

8%  Upregulatedd

hypothetical protein

F09F7.4

175766

11%  Upregulatedd

Protein F09F7.5

F09F7.5

175764

Upregulatedd

hypothetical protein

F11G11.13

184367

20%  Upregulatedd

Protein F13B6.1

F13B6.1

184407

50%  Upregulatedd

Protein F13G3.7

F13G3.7

172478

25%  Upregulatedd

Protein F14B4.3

F14B4.3

172752

15%  Upregulatedd

hypothetical protein

F15B9.6

184523

17%  Upregulatedd

hypothetical protein

F15D3.8

184528

10%  Upregulatedd

Protein F19B6.1

F19B6.1

178181

35%  Upregulatedd

Protein F21H12.1

F21H12.1

174019

Upregulatedd

hypothetical protein

F22D3.5

184826

10%  Upregulatedd

hypothetical protein

F25B3.5

184916

20%  Upregulatedd

Protein F26A3.4

F26A3.4

172525

27%  Upregulatedd

Protein F26E4.4

F26E4.4

259393

17%  Upregulatedd

Protein F26E4.6

F26E4.6

3565338

60%  Upregulatedd

Protein F28B3.5

F28B3.5

172111

30%  Upregulatedd

Protein F33D4.5

F33D4.5

177549

57%  Upregulatedd

Protein F35D2.3

F35D2.3

174229

Upregulatedd

hypothetical protein

F36A2.7

172692

80%  Upregulatedd

Protein F40F8.5

F40F8.5

174702

Upregulatedd

hypothetical protein

F42A6.1

185645

22%  Upregulatedd

Protein F42G10.1

F42G10.1

181214

Upregulatedd

hypothetical protein

F45H10.2

174992

40%  Upregulated >

Protein F49C12.9

F49C12.9

177752

19%  Upregulatedd

Protein F55B11.1

F55B11.1

178381

Upregulatedd

Protein F55B11.3

F55B11.3

178383

Upregulatedd

Protein F55B11.5

F55B11.5

3565591

Upregulatedd

Protein F57B10.3

F57B10.3

172376

20%  Upregulatedd

hypothetical protein

F58F9.7

177386

15%  Upregulatedd

Delta(5) fatty acid desaturase fat-4

fat-4

177819

25%  Upregulatedd

fructose-1,6-bisphosphatase

fbp-1

266822

Upregulatedd

F-box A protein

fbxa-188

185954

13%  Upregulatedd

F-box A protein

fbxa-220

190489

25%  Upregulatedd

Facilitated Glucose Transporter

fgt-1

173525

25%  Upregulatedd

ForKHead transcription factor family

fkh-7

177340

Upregulatedd

FiZzY (CDC20 protein family) homolog

fzy-1

266859

25%  Upregulatedd

Guanylyl CYclase

gcy-18

178237

25%  Upregulatedd

Guanylyl CYclase

gcy-28

172051

Upregulatedd

Guanylyl CYclase

gcy-6

191644

25%  Upregulatedd

Glutamate dehydrogenase

gdh-1

178130

11%  Upregulatedd

GEX Interacting protein

gei-15

180951

13%  Upregulatedd

Abnormal germ line proliferation

glp-1

176286

33%  Upregulatedd

G Protein, Alpha subunit

gpa-1

179546

Upregulated and Downregulated

G Protein, Alpha subunit

gpa-15

172645

20%  Downregulated

G Protein, Alpha subunit

gpa-5

180527

Upregulated and Downregulated

G Protein, Alpha subunit

gpa-6

181442

10%  Upregulatedd

G Protein, Alpha subunit

gpa-8

179731

Upregulated and Downregulated

G Protein, Gamma subunit

gpc-1

181424

10%  Upregulatedd

GPD (glyceraldehyde 3-phosphate dehydrogenase)

gpd-2

3565504

Upregulatedd

Protein GPD-3

gpd-3

180601

5%  Upregulatedd

Glucose-6-Phosphate Isomerase

gpi-1

173227

Upregulatedd

GRound-Like (grd related)

grl-19

176843

27%  Upregulatedd

hypothetical protein

grld-1

176827

10%  Upregulatedd

Protein H06H21.8

H06H21.8

186700

Upregulatedd

Protein H28O16.1

H28O16.1

173134

27%  Upregulatedd

human HCF1 related

hcf-1

177560

40%  Upregulatedd

Homolog of Hedgehog AcylTransferase

hhat-2

190374

50%  Upregulatedd

Histone H4

his-37

179341

4%  Upregulatedd

Protein HMG-4

hmg-4

176052

6%  Upregulatedd

hypothetical protein

hpa-1

186781

30%  Upregulatedd

hypothetical protein

hpa-2

188415

15%  Upregulatedd

Protein HPL-2

hpl-2

176506

17%  Upregulatedd

human HnRNP A1 homolog

hrp-1

177101

49%  Upregulatedd

Him-Three Paralog

htp-3

172099

19%  Upregulatedd

human HUS1 related

hus-1

171939

11%  Upregulatedd

Protein IDH-1

idh-1

177775

Upregulatedd

Protein IDHA-1

idha-1

172655

Upregulatedd

Intermediate filament protein ifa-3

ifa-3

181699

Upregulatedd

Intermediate filament protein ifd-1

ifd-1

187585

Upregulatedd

Initiation Factor 4E (eIF4E) family

ife-1

176755

Upregulatedd

Initiation Factor 4E (eIF4E) family

ife-2

180393

Upregulatedd

Initiation Factor Five (eIF-5A) homologs

iff-1

176373

Upregulatedd

Initiation Factor 4G (eIF4G) family

ifg-1

174322

55%  Upregulatedd

Intermediate filament protein ifp-1

ifp-1

181182

Upregulatedd

IntraFlagellar Transport Associated

ifta-2

189055

50%  Upregulatedd

eIFTwoBeta (eIF2beta translation initiation factor)

iftb-1

172584

Upregulatedd

iglr-1

iglr-1

184720

34%  Upregulatedd

Protein IMPACT homolog

impt-1

173001

16%  Upregulatedd

INSulin related

ins-18

172600

Upregulatedd

INSulin related

ins-21

191689

Upregulatedd

INSulin related

ins-7

191688

12%  Upregulatedd

INneXin

inx-14

172488

Upregulatedd

INneXin

inx-8

178101

19%  Upregulatedd

INneXin

inx-9

191694

28%  Upregulatedd

Iron-Sulfur Protein

isp-1

177609

60%  Upregulatedd

Lysine-specific demethylase 4

jmjd-2

175080

13%  Upregulatedd

Protein K01C8.7

K01C8.7

186841

20%  Upregulatedd

Protein K07H8.1

K07H8.1

177624

Upregulatedd

Protein K07H8.8

K07H8.8

187128

22%  Upregulatedd

Protein K08E3.5

K08E3.5

176814

Upregulatedd

Protein K10B4.3

K10B4.3

173397

Upregulatedd

Protein K11B4.1

K11B4.1

173349

16%  Upregulatedd

Protein K12H4.5

K12H4.5

187337

58%  Upregulatedd

kynu-1

kynu-1

180883

38%  Upregulatedd

Leucyl Amino-acyl tRNA Synthetase

lars-2

172499

Upregulatedd

Lipid Binding Protein

lbp-7

191701

Upregulatedd

LEThal

let-363

172167

150%  Upregulatedd

Protein let-418

let-418

178970

25%  Upregulatedd

hypothetical protein

let-630

172153

18%  Upregulatedd

LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog

letm-1

179854

21%  Upregulatedd

Abnormal cell LINeage

lin-14

181337

31%  Upregulatedd

Protein lin-28

lin-28

172626

20%  Upregulatedd

Protein LIN-5

lin-5

174267

16%  Upregulatedd

Lateral-signal-Induced Phosphatase

lip-1

191704

8%  Upregulatedd

LiPid Depleted

lpd-5

172037

17%  Upregulatedd

LiPid Depleted

lpd-9

179477

10%  Upregulatedd

LYSozyme

lys-10

184622

20%  Upregulatedd

LYSozyme

lys-6

178087

13%  Upregulatedd

MAO-C-like dehydratase domain

maoc-1

174181

Upregulatedd

Methionyl tRNA Synthetase

mars-1

178089

23%  Upregulatedd

Motor AXon guidance

max-1

179794

Upregulatedd

Motor AXon guidance

max-2

3565400

25%  Upregulatedd

Malate DeHydrogenase

mdh-1

179041

4%  Upregulatedd

MAD-Like

mdl-1

180942

16%  Upregulatedd

Protein MECR-1

mecr-1

174963

Upregulatedd

Protein MEL-28

mel-28

175634

6%  Upregulatedd

MEdiator of cell MOtility 1 homolog

memo-1

179163

38%  Upregulatedd

Maternal Effect Sterile

mes-1

181362

60%  Upregulatedd

Histone-lysine N-methyltransferase mes-2

mes-2

175096

6%  Upregulatedd

Protein MFN-1

mfn-1

174752

64%  Upregulatedd

MItoChondrial Scaffolding protei

mics-1

179475

54%  Upregulatedd

mir-238

mir-238

3564977

20%  Upregulatedd

mir-34

mir-34

260162

62%  Upregulatedd

microRNA-80

mir-80

3565575

Upregulatedd

Mitochondrial Rho GTPase 1

miro-1

177238

50%  Upregulatedd

MKK (MAP Kinase Kinase) homolog

mkk-4

185682

Downregulated

Multiple PDZ domain protein

mpz-1

174657

31%  Upregulatedd

Temporarily Assigned Gene name

mpz-2

177736

Upregulatedd

Multidrug Resistance Protein family

mrp-5

181587

Upregulatedd

Protein MRPL-10

mrpl-10

186840

17%  Upregulatedd

Protein MRPL-12

mrpl-12

176495

51%  Upregulatedd

Protein MRPL-2

mrpl-2

176903

54%  Upregulatedd

Protein MRPL-24

mrpl-24

172204

14%  Upregulatedd

Protein MRPL-37

mrpl-37

175001

41%  Upregulatedd

Protein MRPL-47

mrpl-47

172164

20%  Upregulatedd

Protein MRPL-50

mrpl-50

174422

17%  Upregulatedd

Protein MRPS-10

mrps-10

189618

39%  Upregulatedd

Temporarily Assigned Gene name

mrps-30

172957

21%  Upregulatedd

Protein MRPS-33

mrps-33

184770

36%  Upregulatedd

Protein MRPS-5

mrps-5

179721

60%  Upregulatedd

Protein MRPS-9

mrps-9

184267

60%  Upregulatedd

Protein MTCH-1

mtch-1

174207

21%  Upregulatedd

MeTaLlothionein

mtl-2

179899

Upregulatedd

NADC (Na+-coupled dicarboxylate transporter) family

nac-2

187898

19%  Upregulatedd

NADC (Na+-coupled dicarboxylate transporter) family

nac-3

176429

15%  Upregulatedd

asparagiNyl tRNA Synthetase

nars-1

172442

11%  Upregulatedd

Nematode AStacin protease

nas-38

180407

Upregulatedd

hypothetical protein

ndg-4

175582

71%  Upregulatedd

Nucleoside diphosphate kinase

ndk-1

172939

Upregulatedd

NADH Ubiquinone oxidoreductase Fe-S protein

nduf-2.2

188912

20%  Upregulatedd

Nuclear Hormone Receptor family

nhr-14

181102

Upregulatedd

Nuclear Hormone Receptor family

nhr-154

182565

Upregulatedd

Protein NHR-23

nhr-23

172460

5%  Upregulatedd

Protein NHR-265

nhr-265

185603

4%  Upregulatedd

Na/H eXchanger

nhx-2

174242

40%  Upregulatedd

Protein NKCC-1

nkcc-1

3565648

23%  Upregulatedd

NucleOLar protein

nol-1

173437

31%  Upregulatedd

NucleOLar protein

nol-5

171901

15%  Upregulatedd

Nematode Polyprotein Allergen related

npa-1

179095

32%  Upregulatedd

NeuroPeptide Receptor family

npr-1

180752

16%  Upregulatedd

GLIoTactin (Drosophila neuroligin-like) homolog

nrx-1

179503

Downregulated

Nop2 (NOP2)/SUN domain family member

nsun-5

175153

17%  Upregulatedd

Abnormal nuclease

nuc-1

181174

Upregulatedd

NADH Ubiquinone Oxidoreductase

nuo-1

174696

50%  Upregulatedd

NADH Ubiquinone Oxidoreductase

nuo-2

172363

Upregulatedd

NADH Ubiquinone Oxidoreductase

nuo-3

178404

77%  Upregulatedd

NADH Ubiquinone Oxidoreductase

nuo-4

176001

38%  Upregulatedd

NADH Ubiquinone Oxidoreductase

nuo-5

178735

Upregulatedd

Protein NUO-6

nuo-6

172438

73%  Upregulatedd

Osm-9 and Capsaicin receptor-Related

ocr-2

188314

Upregulatedd

hypothetical protein

odr-2

179098

25%  Upregulatedd

ODoRant response abnormal

odr-3

179806

30%  Upregulatedd

Nuclear hormone receptor family member odr-7

odr-7

181403

27%  Upregulatedd

Protein OGDH-1

ogdh-1

177235

79%  Upregulatedd

OSMotic avoidance abnormal

osm-1

181715

40%  Upregulatedd

OSMotic avoidance abnormal

osm-3

177141

Upregulatedd

OSMotic avoidance abnormal

osm-5

180585

150%  Upregulatedd

OSMotic avoidance abnormal

osm-6

179631

40%  Upregulatedd

PolyA Binding protein

pab-1

172920

30%  Upregulatedd

PolyA Binding protein

pab-2

181473

Upregulatedd

Paralysed Arrest at Two-fold

pat-4

175175

24%  Upregulatedd

Paralysed Arrest at Two-fold

pat-6

176848

60%  Upregulatedd

R11A5.4b

pck-2

172556

Upregulatedd

PDK-class protein kinase

pdk-1

180475

60%  Upregulatedd

OligoPeptide Transporter

pept-1

180919

40%  Upregulatedd

Patterned Expression Site

pes-2.1

173025

Upregulatedd

ProFiliN

pfn-2

180808

Upregulatedd

Protein PGHM-1

pghm-1

171746

Upregulatedd

P GranuLe abnormality

pgl-1

177461

Upregulatedd

EGg Laying defective

pkg-1

176991

55%  Upregulatedd

Protein PME-1

pme-1

266823

29%  Upregulatedd

Polarity and Osmotic sensitivity Defect

pod-1

176784

45%  Upregulatedd

POsterior Segregation

pos-1

179224

20%  Upregulatedd

PeRoXisome assembly factor

prx-5

174392

30%  Upregulatedd

Poly(U) Polymerase

pup-2

175708

Upregulatedd

PYruvate Carboxylase

pyc-1

179616

5%  Upregulatedd

glutaminyl(Q) tRNA Synthetase

qars-1

178415

40%  Upregulatedd

hypothetical protein

R07E4.3

180862

20%  Upregulatedd

Protein R08E3.3

R08E3.3

180757

Upregulatedd

Protein R10H10.7

R10H10.7

177932

22%  Upregulatedd

hypothetical protein

R12E2.2

172011

50%  Upregulatedd

Protein R53.4

R53.4

174554

20%  Upregulatedd

RAB family

rab-10

266836

16%  Upregulatedd

Guanine nucleotide-binding protein subunit beta-2-like 1

rack-1

177895

10%  Upregulatedd

RAs-related GTP-binding protein A

raga-1

174726

27%  Upregulatedd

RAs-related GTP binding protein C homolog

ragc-1

178084

26%  Upregulatedd

RAL (Ras-related GTPase) homolog

ral-1

175433

19%  Upregulatedd

Probable arginine--tRNA ligase, cytoplasmic

rars-1

175659

27%  Upregulatedd

Regulator of CAalciNeurin

rcan-1

175788

38%  Upregulatedd

hypothetical protein

rec-8

178295

26%  Upregulatedd

RNA HelicAse

rha-2

176207

32%  Upregulatedd

Protein RHEB-1

rheb-1

176327

19%  Upregulatedd

Resistance to Inhibitors of Cholinesterase

ric-4

179427

Downregulated

RNAi-Induced Longevity

ril-1

179958

32%  Upregulatedd

RNAi-Induced Longevity

ril-2

179725

Upregulatedd

60S acidic ribosomal protein P0

rla-0

172943

7%  Upregulatedd

Regulation of Longevity by E3 ubiquitin ligase

rle-1

176525

Upregulatedd

RiNg Finger protein

rnf-5

175532

Upregulatedd

Protein RNR-2

rnr-2

175525

14%  Upregulatedd

Protein RPA-1

rpa-1

174238

5%  Upregulatedd

Protein RPB-8

rpb-8

175660

6%  Upregulatedd

RNA Polymerase, Class III

rpc-1

177491

36%  Upregulatedd

60S ribosomal protein L10a

rpl-1

171853

23%  Upregulatedd

60S ribosomal protein L10

rpl-10

174311

20%  Upregulatedd

60S ribosomal protein L17

rpl-17

171692

13%  Upregulatedd

Ribosomal Protein, Large subunit

rpl-19

172201

Upregulatedd

60S ribosomal protein L23

rpl-23

175796

18%  Upregulatedd

60S ribosomal protein L3

rpl-3

175501

29%  Upregulatedd

Ribosomal Protein, Large subunit

rpl-30

172921

13%  Upregulatedd

60S ribosomal protein L31

rpl-31

173235

16%  Upregulatedd

Ribosomal Protein, Large subunit

rpl-4

172074

Upregulatedd

60S ribosomal protein L7

rpl-7

171602

10%  Upregulatedd

60S ribosomal protein L7a

rpl-7A

177203

12%  Upregulatedd

Ribosomal Protein, Large subunit

rpl-9

176071

Upregulatedd

40S ribosomal protein SA

rps-0

175628

15%  Upregulatedd

Ribosomal Protein, Small subunit

rps-10

172061

Upregulatedd

Ribosomal Protein, Small subunit

rps-11

178083

30%  Upregulatedd

Protein RPS-12

rps-12

175786

12%  Upregulatedd

Protein RPS-14

rps-14

176006

17%  Upregulatedd

Ribosomal Protein, Small subunit

rps-15

172693

50%  Upregulatedd

40S ribosomal protein S16

rps-16

179998

8%  Upregulatedd

Ribosomal Protein, Small subunit

rps-20

173309

24%  Upregulatedd

Ribosomal Protein, Small subunit

rps-22

175338

Upregulatedd

Ribosomal Protein, Small subunit

rps-23

178188

126%  Upregulatedd

Ribosomal Protein, Small subunit

rps-26

173342

Upregulatedd

Ribosomal Protein, Small subunit

rps-3

175879

32%  Upregulatedd

Ribosomal Protein, Small subunit

rps-5

178012

75%  Upregulatedd

Ribosomal Protein, Small subunit

rps-6

173260

Upregulatedd

Ribosomal Protein, Small subunit

rps-8

177503

18%  Upregulatedd

RSK-pSeventy (RSK-p70 kinase) homolog

rsks-1

176554

47%  Upregulatedd

Protein RSR-1

rsr-1

173013

6%  Upregulatedd

S-Adenosyl Methionine Synthetase

sams-1

181370

15%  Upregulatedd

 

sams-2

178446

27%  Upregulatedd

hypothetical protein

sams-3

177355

50%  Upregulatedd

Spindle ASsembly abnormal

sas-5

179592

30%  Upregulatedd

SERCA (Sarco-Endoplasmic Reticulum Calcium ATPase)

sca-1

176512

19%  Upregulatedd

SCP-Like extracellular protein

scl-4

183342

Upregulatedd

SCP-Like extracellular protein

scl-8

183345

18%  Upregulatedd

Protein SCO-1

sco-1

173763

23%  Upregulatedd

SCRaMblase (phospholipid scramblase)

scrm-8

187152

Upregulatedd

Suppressor/Enhancer of Lin-12

sel-5

175599

29%  Upregulatedd

SEx Muscle abnormal

sem-5

181055

24%  Upregulatedd

SERotonin/octopamine receptor family

ser-1

181716

46%  Upregulatedd

SET (trithorax/polycomb) domain containing

set-15

187813

10%  Upregulatedd

SET (trithorax/polycomb) domain containing

set-2

175662

30%  Upregulatedd

SET (trithorax/polycomb) domain containing

set-26

178463

22%  Upregulatedd

SET (trithorax/polycomb) domain containing

set-4

174045

20%  Upregulatedd

SET (trithorax/polycomb) domain containing

set-9

177196

22%  Upregulatedd

Serum- and Glucocorticoid- inducible kinase homolog

sgk-1

181697

Upregulatedd

Systemic RNA Interference Defective

sid-2

176805

Upregulatedd

SIN-1 (S. pombe stress activated protein kinase interactor) Homolog

sinh-1

190339

Upregulatedd

SKp1 Related (ubiquitin ligase complex component)

skr-5

180148

10%  Upregulatedd

hypothetical protein

slcf-1

186633

40%  Upregulatedd

hypothetical protein

sma-10

176849

30%  Upregulatedd

Suppressor with Morphological effect on Genitalia

smg-1

172418

30%  Upregulatedd

superoxide dismutase

sod-1

174141

Upregulatedd

Defective SPErmatogenesis

spe-26

177929

65%  Upregulatedd

Temporarily Assigned Gene name

spe-5

172137

23%  Upregulatedd

human SPG (spastic paraplegia)

spg-7

171915

23%  Upregulatedd

SaPosin-like Protein family

spp-17

171681

20%  Upregulatedd

Suppressor of presenilin protein 3

spr-3

180722

26%  Upregulatedd

SPT transcription factor family

spt-4

175172

Upregulatedd

Serine Palmitoyl Transferase famiLy

sptl-1

173389

33%  Upregulatedd

Serpentine Receptor, class T

srt-56

190663

30%  Upregulatedd

Serpentine Receptor, class U

sru-17

188048

Upregulatedd

Serpentine Receptor, class W

srw-100

189964

Upregulatedd

Serpentine Receptor, class W

srw-20

188136

Upregulatedd

Serpentine Receptor, class W

srw-99

189965

Upregulatedd

Protein SYMK-1

symk-1

182490

24%  Upregulatedd

Protein T02H6.11

T02H6.11

173459

60%  Upregulatedd

T05A1.5b

T05A1.5

188077

20%  Upregulatedd

Protein T07A9.8

T07A9.8

176864

24%  Upregulatedd

hypothetical protein

T12E12.1

177339

30%  Upregulatedd

INSulin related

T15B12.1

188527

40%  Upregulatedd

Protein T20H4.5

T20H4.5

176023

51%  Upregulatedd

Protein T23D8.3

T23D8.3

172857

26%  Upregulatedd

hypothetical protein

T25B9.1

177968

Upregulatedd

hypothetical protein

T27E9.2

176772

20%  Upregulatedd

Protein T28A8.6

T28A8.6

176780

28%  Upregulatedd

Protein T28D6.4

T28D6.4

176566

33%  Upregulatedd

Temporarily Assigned Gene name

tag-174

175693

25%  Upregulatedd

Transaldolase

tald-1

177202

14%  Upregulatedd

Threonyl Amino-acyl tRNA Synthetase

tars-1

174790

12%  Upregulatedd

Tyrosine AminoTraNsferase

tatn-1

181574

10%  Upregulatedd

Abnormal chemotaxis

tax-4

176297

100%  Upregulatedd

Abnormal chemotaxis

tax-6

177943

27%  Upregulatedd

Tubulin alpha chain

tba-4

174680

Upregulatedd

TuBulin, Alpha

tba-7

176568

13%  Upregulatedd

Tubulin beta-2 chain

tbb-2

175519

5%  Upregulatedd

Protein TDP-1

tdp-1

174436

20%  Upregulatedd

Temporarily Assigned Gene name

tes-1

177515

60%  Upregulatedd

Protein TKT-1

tkt-1

177906

25%  Upregulatedd

TPA (tetradecanoyl phorbol acetate) resistant

tpa-1

176825

28%  Upregulatedd

Protein TRIM-9

trim-9

178619

Upregulatedd

TRYpsin-like protease

try-1

173856

Upregulatedd

TetraSPanin 3

tsp-3

192059

41%  Upregulatedd

Putative sphingolipid delta(4)-desaturase/C4-hydroxylase

ttm-5

173327

40%  Upregulatedd

TransThyretin-Related family domain

ttr-1

186958

19%  Upregulatedd

TransThyretin-Related family domain

ttr-5

176312

14%  Upregulatedd

TUBby-related

tub-1

174312

Upregulatedd

TU elongation Factor (EF-Tu), Mitochondrial

tufm-1

175398

89%  Upregulatedd

UBiquitin C-terminal Hydrolase

ubh-4

174289

Upregulatedd

Ubiquinol-Cytochrome c oxidoReductase complex

ucr-1

175772

110%  Upregulatedd

Ubiquinol-Cytochrome c oxidoReductase complex

ucr-2.3

175248

15%  Upregulatedd

Uterine Lumin Expressed/locailized

ule-1

171778

24%  Downregulated

Uterine Lumin Expressed/locailized

ule-2

4927009

26%  Downregulated

Uterine Lumin Expressed/locailized

ule-3

179497

27%  Downregulated

UPF0375 protein C08F11.11

ule-4

178331

26%  Downregulated

Uterine Lumin Expressed/locailized

ule-5

181365

27%  Downregulated

UNCoordinated

unc-10

180990

Downregulated

UNCoordinated

unc-13

172497

150%  Upregulatedd

UNCoordinated

unc-26

178284

50%  Upregulatedd

UNCoordinated

unc-31

178233

150%  Upregulatedd

UNCoordinated

unc-32

176257

Upregulatedd

unc-36

unc-36

176155

34%  Upregulatedd

UNCoordinated

unc-52

175126

11%  Upregulatedd

UNCoordinated

unc-62

178845

38%  Upregulatedd

UNCoordinated

unc-83

179033

Upregulatedd

Protein UTX-1

utx-1

181110

30%  Upregulatedd

Protein VANG-1

vang-1

180579

40%  Upregulatedd

Vacuolar H ATPase

vha-6

174743

24%  Upregulatedd

von Hippel-Lindau tumor suppressor homolog

vhl-1

181321

30%  Upregulatedd

Vitellogenin-1

vit-1

181034

40%  Upregulatedd

VITellogenin structural genes (yolk protein genes)

vit-2

180781

Upregulatedd

VITellogenin structural genes (yolk protein genes)

vit-5

180630

Upregulatedd

Protein W03G1.5

W03G1.5

189167

54%  Upregulatedd

hypothetical protein

W03G1.8

189168

20%  Upregulatedd

Worm AIF (apoptosis inducing factor) Homolog

wah-1

176635

13%  Upregulatedd

WD Repeat protein

wdr-23

172518

24%  Upregulatedd

Temporarily Assigned Gene name

wdr-5.1

175474

30%  Upregulatedd

WarTS (Drosophila) protein kinase homolog

wts-1

172896

21%  Upregulatedd

Transaldolase

Y24D9A.8

177202

26%  Upregulatedd

Protein Y37D8A.12

Y37D8A.12

176705

Upregulatedd

Protein Y39H10A.6

Y39H10A.6

178791

Upregulatedd

hypothetical protein

Y43C5A.3

189848

20%  Upregulatedd

Protein Y43F4B.7

Y43F4B.7

259544

11%  Upregulatedd

Protein Y43H11AL.2

Y43H11AL.2

3565323

Upregulatedd

Protein Y46H3C.6

Y46H3C.6

189968

Upregulatedd

Protein Y48G1A.4

Y48G1A.4

171622

21%  Upregulated >

Protein Y54E5A.7

Y54E5A.7

173332

Upregulatedd

hypothetical protein

Y54G9A.7

175017

12%  Upregulatedd

Protein Y56A3A.19

Y56A3A.19

176622

37%  Upregulated >

Y56A3A.9

Y56A3A.9

190326

Upregulatedd

Protein Y65B4BR.5

Y65B4BR.5

171646

17%  Upregulatedd

hypothetical protein

Y71H2AM.5

3565081

40%  Upregulatedd

Protein Y71H2AR.2

Y71H2AR.2

190615

Upregulatedd

YARS-1

yars-1

177237

55%  Upregulatedd

Protein ZC132.3

ZC132.3

178827

26%  Upregulatedd

Protein ZK1127.5

ZK1127.5

174151

24%  Upregulated >

Protein ZK686.2

ZK686.2

176088

24%  Upregulatedd

Protein ZK809.3

ZK809.3

178096

100%  Upregulatedd

Reference: HAGR