Retinoic acid receptor alpha (RAR alpha)

 Testis degeneration
 Early postnatal lethality

Lufkin et al., 1993


METHODOLOGY ( FROM T-BASE)

((rar))

Line Name DNA Construct
1. RAR alpha1 (+/-) For RAR alpha1 (retinoic acid receptor alpha1) isoform disruption, a 9-kb EcoRV-Sall fragment from lambda-G1mRARalpha was subcloned into pBluescript KS(+) to....
2. RAR alpha (+/-) For full RAR alpha (retinoic acid receptor alpha) disruption, an 11kb EcoRl-Spel fragment (containing the A2 and B regions) from lambdaG2mRAR alpha was subcloned into th....
3. RAR alpha1 (-/-) For RAR alpha1 (retinoic acid receptor alpha1) isoform disruption, a 9-kb EcoRV-Sall fragment from lambda-G1mRARalpha was subcloned into pBluescript KS(+) to....
4. RAR alpha (-/-) For full RAR alpha (retinoic acid receptor alpha) disruption, an 11kb EcoRl-Spel fragment (containing the A2 and B regions) from lambdaG2mRAR alpha was subcloned into th....
5. RARalpha1 (+/-) For the construction of the targeting vector, genomic clones were isolated from a DBA/2 mouse liver genomic library (Clontech) screened with a RAR(retinoic acid receptor....
6. RARalpha1 (-/-) For the construction of the targeting vector, genomic clones were isolated from a DBA/2 mouse liver genomic library (Clontech) screened with a RAR(retinoic acid receptor....


Database links

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors