Pxr1

Lack of morphologically identifiable peroxisomes
Intrauterine growth retardation
Severe hypotomia at birth
Impaired neuronal migration and maturation and extensive apoptotic death of neurons
Death within 72 hours after birth

Reference:

Baes M., Gressens P., Baumgart E., Carmeliet P., asteels M., Fransen M., Evrard P., Fahimi D., Declerq PE, Collen D., van Veldhoven PP, Mannaerts GP.: A mouse model for Zellweger syndrome. Nat Genet 1997 Sep;17 (1):49-57.

Pxr1 (+/-)	The Pxr1 mouse cDNA was isolated by reverse transcriptase--PCR on mouse-liver RNA with primers based on the human PXR1 sequence (forward primer 5'-CAGGCAGAACAGTGGGCAG....
Pxr1 (-/-)	The Pxr1 mouse cDNA was isolated by reverse transcriptase--PCR on mouse-liver RNA with primers based on the human PXR1 sequence (forward primer 5'-CAGGCAGAACAGTGGGCAG....