P-Selectin and ICAM-1

Normal neutrophil emigration into the alveolar spaces during acute Streptococcus pneumoniae-induced peritonitis
Complete loss of acute neutrophil emigration into the peritoneum during S. pneumoniae-induced peritonitis

Bullard et al, 1995

( (p-selectin))

	Line Name	DNA Construct
1.	P-selectin (+/-)	An amplified mouse genomic library constructed from the liver DNA of black agouti 129Sv mouse strain (kindly provided by Drs. H. Wu and R. Jaenisch (G00-100-762) was scr....
2.	Sele (-/-)	Murine E-selectin genomic clones were isolated from lambda libraries derived from either 129SV DNA (Stratagene, Incorporated) or BALB/c DNA (Clonetec, Incorporated). In....
3.	P-selectin (-/-)	An amplified mouse genomic library constructed from the liver DNA of black agouti 129Sv mouse strain (kindly provided by Drs. H. Wu and R. Jaenisch (G00-100-762) was scr....

((icam-1))

	Line Name	DNA Construct
1.	K14/ICAM-1 I13	A 1.9-kb cDNA for mouse ICAM-1 containing all coding sequences and a stop codon, was converted into a BamHI fragment with linkers and cloned into a single
2.	K14/ICAM-1 I31	A 1.9-kb cDNA for mouse ICAM-1 containing all coding sequences and a stop codon, was converted into a BamHI fragment with linkers and cloned into a single
3.	K14/ICAM-1 I12	A 1.9-kb cDNA for mouse ICAM-1 containing all coding sequences and a stop codon, was converted into a BamHI fragment with linkers and cloned into a single
4.	K14/ICAM-1 I21	A 1.9-kb cDNA for mouse ICAM-1 containing all coding sequences and a stop codon, was converted into a BamHI fragment with linkers and cloned into a single
5.	ICAM-1 (+/-)	To prepare the targeting construct, a 5.5-kb segment of the ICAM-1 gene containing exons 4-7 was cloned into pBluescript ll KS(--) (Stratagene). A neomycin-resistance....
6.	ICAM-1 (-/-)	To prepare the targeting construct, a 5.5-kb segment of the ICAM-1 gene containing exons 4-7 was cloned into pBluescript ll KS(--) (Stratagene). A neomycin-resistance....