Immunodeficiency characterized by impairment of humoral immune
Reduction in cellular responses of B cells

Leitges, C. Schmedt, R. Guinamard, J. Davoust, S. Schaal, S. Stabel & A. Tarakhovsky:
Immunodeficiency in Protein Kinase C beta-Deficient Mice.
Science 273, 789 (1996)