Platelet-derived growth factor B (PDGF B)
Lack of formation of kidney glomerular tufts
Dilation of heart and some large arteries in late stage embryos
Erythroblastosis
Macrocytic anemia
Thrombocytopenia
High rate of fatal hemorrhage
Perinatal death
| Line Name | DNA Construct | |
|---|---|---|
| 1. | V717F beta-amyloidP | A platelet-derived growth factor (PDGF)-beta promoter was used to drive a human beta-amyloid precursor protein (hAPP) minigene encoding the APP(717V-->F) mutation associ.... |
