Increased primary responses to Leishmania major
Increased secondary responses to ovalbumin, in vitro
Increased accumulation of eosinophils and serum levels immunoglobulin E, in vivo

Xanthoudakis, 1996

An enhanced immune response in mice lacking the transcription factor NFAT1.
Science 272, 892-895 (1996) [96217952]

((nfat1))

	Line Name	DNA Construct
1.	NFAT1 (+/-)	NFAT1 gene fragments were cloned from a genomic library derived from mouse strain 129/Sv (Stratagene). A 4.5-kb region of the NFAT1 gene was deleted by XhoI....
2.	NFAT1 (-/-)	NFAT1 gene fragments were cloned from a genomic library derived from mouse strain 129/Sv (Stratagene). A 4.5-kb region of the NFAT1 gene was deleted by XhoI....