Lama2

 Growth retardation
 Severe muscular dystrophic symptoms
 Muscle fiber degeneration and apoptosis fiber
 Death by 5 weeks of age

Reference:

Miyagoe Y, Hanaoka K, Nonaka I, Hayasaka M, Nabeshima Y, Arahata K, Nabeshima Y, Takeda S.: Laminin alpha2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin2)-deficient congenital muscualr dystrophy. FEBS Lett 1997 Sep22;415 (1):33-39.


METHODOLOGY ( FROM T-BASE)


Database Links

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