Krox-20

 Marked reduction or elimination of rhombomeres 3 and 5 in the developing hindbrain
 Fusion of the trigeminal ganglion with the facial and vestibular ganglia
 Fusion of the superior ganglia of glossopharyngeal and vagus nerves
 Death during first two weeks after birth

Schneider-Maunoury et al., 1993
Swiatek and Gridley, 1993


METHODOLOGY ( FROM T-BASE)

((krox-20))

Line Name DNA Construct
1. Krox-20 (-/-) A 10-kb genomic fragment spanning the Krox-20 gene from the BglII site located 4 kb 5' of the transcription initiation site of the SpeI site locate....
2. Krox-20 (+/-) A 10-kb genomic fragment spanning the Krox-20 gene from the BglII site located 4 kb 5' of the transcription initiation site of the SpeI site locate....
3. Krox-20 (-/-) A 10-kb genomic fragment spanning the Krox-20 gene from the BglII site located 4 kb 5' of the transcription initiation site of the SpeI site locate....


Database links

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors