Int- 2

Defects in development of tail and inner ear
Low rate of survival to adulthood

Mansour et al., 1993

((int-2))

	Line Name	DNA Construct
1.	int-2(neo) (+/-)	The int-2 gene (also designated Fgf-3 for Fibroblast growth factor-3) is a member of the fibroblast growth factor (FGF) family. The neo(r) gene employed in this study w....
2.	int-2-lac-Z (+/-) E	The int-2-lac-Z replacement vector, pINT-2-LACZN/TK, was constructed by starting with pINT-2-NpA, which contains a 10-kb EcoRI fragment of int-2 genomic DNA d....
3.	Hox-A1(+/-), int-2+	Mice carrying a targeted E. coli lac-Z insertion into the int-2 gene (int-2(lacZ)) were generated (G00-387-368). The int-2 gene (also designated Fgf-3 for Fibroblast gr....
4.	Hox-A1(-/-), int-2+	Mice carrying a targeted E. coli lac-Z insertion into the int-2 gene (int-2(lacZ)) were generated (G00-387-368). The int-2 gene (also designated Fgf-3 for Fibroblast gr....
5.	int-2(neo) (-/-)	The int-2 gene (also designated Fgf-3 for Fibroblast growth factor-3) is a member of the fibroblast growth factor (FGF) family. The neo(r) gene employed in this study w....