Insulin (Ins1, Ins2)

Growth retardation
Lack of glycosuria at birth
Diabetes with ketoacidosis and liver steatosis
Diabetes mellitus soon after suckling
Beta cells and glucagon positive cells present
Somatostatin and pancreatic polypeptide mRNAs present at reduced levels
Enlargement of islets of Langerhans
Death within 48 hours after birth

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