IL-1ß

Viable
Normal inflammatory response to systemic LPS administration
No acute-phase response to subcutaneous turpentine injection

( (il1b))

	Line Name	DNA Construct
1.	Il1b (+/-)	The deletion targeting vector contained a 4.2 kb BamHI fragment upstream of the ATG translation initiation codon and a 1.3 kb KpnI-BglII....
2.	Il1b (+/-)	The deletion targeting vector contained a 4.2 kb BamHI fragment upstream of the ATG translation initiation codon and a 1.3 kb KpnI-BglII....
3.	IL-1-beta (+/-)	A 4.6-kb EcoRI to EcoRV fragment containing exons 1 through 5 of the IL-1-beta gene was subcloned from cosmid beta7.1 into EcoRI- and
4.	Il1b (-/-)	The deletion targeting vector contained a 4.2 kb BamHI fragment upstream of the ATG translation initiation codon and a 1.3 kb KpnI-BglII....
5.	IL-1-beta (-/-)	A 4.6-kb EcoRI to EcoRV fragment containing exons 1 through 5 of the IL-1-beta gene was subcloned from cosmid beta7.1 into EcoRI- and
6.	Il1b (-/-)	The deletion targeting vector contained a 4.2 kb BamHI fragment upstream of the ATG translation initiation codon and a 1.3 kb KpnI-BglII....