Insulin-like growth factor type 2 (Igf2) receptor
Organ and skeletal abnormalities
Missorting of mannose-6-phosphage tagged proteins
Lethality at birth
| Line Name | DNA Construct | |
|---|---|---|
| 1. | Igf2r (m-/p-) homoz | A 20-kb fragment of the mouse Igf2r (insulin-like growth factor-II/cation-independent mannose-6-phosphate receptor) gene containing exons 8-22 was isolated by screening.... |
| 2. | Igf2r (m-/p+) heter | A 20-kb fragment of the mouse Igf2r (insulin-like growth factor-II/cation-independent mannose-6-phosphate receptor) gene containing exons 8-22 was isolated by screening.... |
