Hoxd-13
Skeletal abnormalities along all body axes
Limb abnormalities
Reduction in length of some bony elements
Loss of phalanges
Bone fusions
Presence of extra elements
| Line Name | DNA Construct | |
|---|---|---|
| 1. | Hoxd-13 (+/-) | A replacement type targeting vector was designed so that homologous recombination resulted in the disruption of the homeodomain after the first 11th residues. The neo(r.... |
| 2. | Hoxd-13 (-/-) | A replacement type targeting vector was designed so that homologous recombination resulted in the disruption of the homeodomain after the first 11th residues. The neo(r.... |
