Hoxb-4

 Partial homeotic transformation of second cervical vertabra from axis to atlas
 Defective morphogenesis of sternum

Ramirez-Solis et al., 1993


METHODOLOGY ( FROM T-BASE)

((hoxb-4))

Line Name DNA Construct
1. Hoxb-4(r) (Hox-2.6) The replacement-type targeting vector to generate the hxob-4(r) allele (pHZ007) contained a 3.1 kb EcoRI-BamHI fragment of genomic Hoxb-4 DNA that....
2. Hoxb-4(r) (Hox-2.6) The replacement-type targeting vector to generate the hxob-4(r) allele (pHZ007) contained a 3.1 kb EcoRI-BamHI fragment of genomic Hoxb-4 DNA that....
3. Hoxb4(s) (+/-) pRRH11 is an insertion vector that contains a 3.1-kb Hox-2.6 fragment. This includes the two exons of the gene that have been modified by the introduction of the oligon....
4. Hoxb4(s) (-/-) pRRH11 is an insertion vector that contains a 3.1-kb Hox-2.6 fragment. This includes the two exons of the gene that have been modified by the introduction of the oligon....


Database links

OMIM Gene Map GDB