Hoxa-4

 Mutant mice are viable
 Mutant mice are fertile
 Low rate of alteration in sternal morphogenesis

Horan et al., 1994


METHODOLOGY ( FROM T-BASE)

((hoxa-4))

Line Name DNA Construct
1. Hoxa-4 (+/-) A gene-targeting vector was generated from a lambda phage DNA clone containing the Hoxa-4 gene previously isolated from a C57BL/6J (B6) mouse genomic library. The vecto....
2. Hoxa-4 (-/-) A gene-targeting vector was generated from a lambda phage DNA clone containing the Hoxa-4 gene previously isolated from a C57BL/6J (B6) mouse genomic library. The vecto....
3. Hoxb-4(r) (Hox-2.6) The replacement-type targeting vector to generate the hxob-4(r) allele (pHZ007) contained a 3.1 kb EcoRI-BamHI fragment of genomic Hoxb-4 DNA that....
4. Hoxd-4 (+/-) A replacement gene targeting vector was generated from a cosmid clone designated "cosE" containing the Hoxd-4 gene previously isolated from a 129/Sv cosmid genomic libra....
5. Hoxd-4 (-/-) A replacement gene targeting vector was generated from a cosmid clone designated "cosE" containing the Hoxd-4 gene previously isolated from a 129/Sv cosmid genomic libra....


Database links

Gene Map GDB