Hoxa-1

Strong reduction in Hoxb-1 and Krox-20 transcripts in a limited area of the hindbrain
Severe defects in the formation of the hindbrain
Severe defects in the formation of cranial ganglia and nerves
Reorganization of the hindbrain

Dolle et al., 1993
Carpenter et al., 1993

((hoxa-1))

	Line Name	DNA Construct
1.	Hoxa-1 (-/-)	An 8.4-kb EcoRI genomic fragment spanning from 6.8-kb 5' to the Hox-1.6 transcription initiation site to nucleotide 1235 located in the Hox-1.6 3' transcribed....