Ftz-F1
Normal survival in utero
Lack of adrenal glands
Lack of gonads
Severe deficiency in corticosterone
Female internal genitalia in both males and females
Postnatal mortality (on day 8)
| Line Name | DNA Construct | |
|---|---|---|
| 1. | Ftz-F1 (+/-) | Genomic sequences containing the Ftz-F1 (fuzi tarazu factor 1-designated as such due to its resemblance to FTZ-F1, an orphan nuclear receptor isolated from Drosophila) c.... |
| 2. | Ftz-F1 (-/-) | Genomic sequences containing the Ftz-F1 (fuzi tarazu factor 1-designated as such due to its resemblance to FTZ-F1, an orphan nuclear receptor isolated from Drosophila) c.... |
| 3. | Ftz-F1 (+/-) | Genomic sequences containing the Ftz-F1 coding sequence were isolated from a 129 mouse genomic library, and a 10-kb region of the phage insert was subcloned and used to.... |
| 4. | Ftz-F1 (-/-) | Genomic sequences containing the Ftz-F1 coding sequence were isolated from a 129 mouse genomic library, and a 10-kb region of the phage insert was subcloned and used to.... |
| 5. | Ftz-F1(+/-) | Genomic sequences containing the Ftz-F1 (fuzi tarazu factor 1-designated as such due to its resemblance to FTZ-F1, an orphan nuclear receptor isolated from Drosophila) c.... |
| 6. | Ftz-F1 (-/-) | Genomic sequences containing the Ftz-F1 (fuzi tarazu factor 1-designated as such due to its resemblance to FTZ-F1, an orphan nuclear receptor isolated from Drosophila) c.... |
