FcR gamma chain
Normal populations of thymic and peripheral T cells
Inability of activated macrophages to phagocytose antibody-coated particles, despite normal binding
Defective NK cell-mediated antibody-dependent cytotoxicity
Defective mast cell-mediated allergic responses
Takai et al., 1994
| Line Name | DNA Construct | |
|---|---|---|
| 1. | FcR-gamma (+/-) | Phage clones spanning the mouse FcR (Fc receptor) gamma subunit gene were isolated from the genomic library of 129/Ola origin (te Riele et al.., 1990; G00-373-065) using.... |
| 2. | FcR-gamma (-/-) | Phage clones spanning the mouse FcR (Fc receptor) gamma subunit gene were isolated from the genomic library of 129/Ola origin (te Riele et al.., 1990; G00-373-065) using.... |
