E-cadherin

 Failure to form trophectoderm epithelium
 Death around the time of implantation

Larue et al., 1994


METHODOLOGY ( FROM T-BASE)

((e-cadherin))

Line Name DNA Construct
1. E-cadherin (+/-) E-cadherin DNA was isolated from a 129/J genomic library; mouse cDNA corresponding to positions 953-1322 was used as a probe. The targeting vector was constructed by st....
2. E-cadherin (-/-) E-cadherin DNA was isolated from a 129/J genomic library; mouse cDNA corresponding to positions 953-1322 was used as a probe. The targeting vector was constructed by st....
3. E-cad (-/-) To construct the pKOUNS3 plasmid, the 5' NsiI-SacI fragment (positions -991 to +96) and the 3' SacI-AccI fragment (positions....
4. E-cad (+/-) To construct the pKOUNS3 plasmid, the 5' NsiI-SacI fragment (positions -991 to +96) and the 3' SacI-AccI fragment (positions....


Database links

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB MEDLINE Neighbors