Bcl-x

 Extensive apoptosis of neurons in brain, spinal cord and dorsal root ganglia
 Apoptosis of hematopoietic cells in liver
 Diminished maturation of lymphocytes
 Death of embryo around Day 13
Motoyama, 1995
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice.
Science 267, 1506-1510 (1995) [95184013]
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METHODOLOGY ( FROM T-BASE)

( (bcl-x))

Line Name DNA Construct
1. AATbcl2#32 A 2.9-kb DNA fragment containing an internal poliovirus sequence (ribosome landing pad) followed by a CAT gene and a SV40 poly(A) sequence was purified after PstI


Database links

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