B cell (µMT/µMT)

 Viable
 CD4+ T cells respond in vitro to B cell antigen (Ag) presentation
 Peripheral tolerance to Ag in vivo shown by loss of T cell proliferation and cytokine production


METHODOLOGY ( FROM T-BASE)

( (mumt))

Line Name DNA Construct
1. muMT/muMT The vector used for the disruption of one of the membrane exons (muM) on B lymphocytes contains 9 kb of genomic DNA spanning exons 1 and 2 of muM and the first three exo....
2. muMT/muMT (& alleli The vector used for the disruption of one of the membrane exons (muM) on B lymphocytes contains 9 kb of genomic DNA spanning exons 1 and 2 of muM and the first three exo....
3. muMT/+ (& allelic e The vector used for the disruption of one of the membrane exons (muM) on B lymphocytes contains 9 kb of genomic DNA spanning exons 1 and 2 of muM and the first three exo....
4. muMT/+ The vector used for the disruption of one of the membrane exons (muM) on B lymphocytes contains 9 kb of genomic DNA spanning exons 1 and 2 of muM and the first three exo....