Apc(delta716)

 Intestinal polyps
 Reduced polyp formation by low fat, high fiber diet

Reference:

Hioki K, Shivapurkar N, Oshima H, Alabaster O, Oshima M, Taketo MM.:Suppression of intestinal polyp development by low-fat and high fiber diet in Apc(delata716) knockout mice. Carcinogenesis 1997 Oct;18 (10):1863-1865.


METHODOLOGY ( FROM T-BASE)

cis Apc (delta-716) A 6.8 kb StuI-XhoI fragment containing exons 2, 3, and 4 was isolated for the long homology arm, another


Database Links

OMIM MEDLINE Citations Protein Links Nucleotide Links Gene Map GDB