FRONTIERS IN BIOSCIENCE;
URINE



Table of Conents

 

TYPICAL REFERENCE INTERVALS

COMPONENT

SYSTEM

CONVENTIONAL UNITS

FACTOR

RECOMMENDED SI UNITS

Acetoacetic acid

Random

Negative

--

Negative

Acetone

Random

Negative

--

Negative

Addis count

12 h collection

     
   

WBC and epithelial cells: 1,800,000/12 h

1

1.8 x 106/12h

   

RBC 500,000/12 h

1

0.5 x 106/12h

   

Hyaline casts: <5000/12 h

1

<5.0 x 103/12 h

Albumin

 

 

 

 

Qualitative

Random

Negative

--

Negative

Quantitative

24 h

15-150 mg/d

0.001

0.015-0.150 g/d

Aldosterone

24 h

2-26 mg/d

2.774

6-72 nmol/d

Alkapton bodies

Random

Negative

--

Nagative

a- Amino acid nitrogen

24 h

100-290 mg/d

0.07139

7.1-20.7 mmol/d

d-Aminoevulinic acid

24 h

     
 

Random

0.1-0.6 mg/dl

76.26

8-46 mmol/L

 

Adult

<o.5 mg/dL

7.626

<38 mmol/L

 

Children

1.5 - 7.5 mg/d

 

11-57 mmol/d

Ammonia nitrogen

24 h

20-70 mEq/d

500-1200 mg/d

1

0.07139

20-70 mmol/d

35.6-85.7 mmol/d

Amylase

2 h

35-260 Somogyi units/h

0.1850

6.5-48.1 U/h

Arsenic

24 h

<50 mg/L

0.01335

<0.67 mmol/L

Ascorbic acid

       
 

Random

1-7 mg/dL

56.78

57-397 mmol/L

 

24 h

>50 mg/d

5.678

>284 mmol/d

Bence Jones protien

Random

Negative

--

Negative

Beryllium

24 h

< 0.05 mg/d

111.0

<5.555 nmol/d

Bilirubin, qualitative

Random

Negative

__

Negative

Blood, occult

Random

Negative

__

Negative

Borate

24 h

<2mg/L

16.44

<32 mmol/L

Calcium

 

 

 

 

Qualitative(Sulkowitch)

Random

1 + turbidity

1

1 + turbidity

Quantitative

Average diet (24 h)

100-240 mg/d

0.02495

2.5-6.0 mmol/d

 

low calcium diet (24 h)

< 150 mg/d

 

 

 

high calcium diet (24 h)

240-300 mg/d

 

 

Catecholamines

Random

< 14 mg/dL

59.11*

<828 nmol/L

 

24 h

<100 mg/d (varies with activity)

5.911*

<591 nmol/d

Epinephrine

 

<10 ng/d

5.458

<55 nmol/d

Norepinephrine

 

<100 ng/d

5.911

<591 nmol/d

Total free catecholamines

 

4-126 mg/d

5.911*

24-745 nmol/d

Total metanephrines

 

0.1-1.6 mg/d

5.458+

0.5-8.7 mmol/d

Chloride

24 h

140-250 mEq/d

1

140-250 nmol/d

Concentration test (Fishberg)

Random--after fluid restriction

   

 

Specific gravity

 

>1.025

1

>1.025

Osmolality

 

>850 mOsm/kg

1

>850 mmol/kg

Copper

24 h

<50 mg/d

0.01574

<0.8 mmol/d

Coproporphyrin

 

 

 

 

 

Random, Adult

3-20 mg/dL

15.27

46-305 nmol/L

 

Adult, 24 hr

50-160 mg/d

1.527

76-244 nmol/d

 

Children, 24 hr

<80 mg/d

 

<122 nmol/d

Creatine

 

 

 

 

 

Male, 24 hr

<40 mg/d

7.625

<305 mmol/d

 

Female, 24 hr

<100 mg/d

higher in children and during pregnancy

--

<763 mmol/d

higher in children and during pregnancy

Creatinine

 

 

 

 

 

Male, 24 hr

20-26 mg/kg/d

1.0-2.0 g/d

8.840

8.840

177-230 mmol/kg/d

8.8-17.7 mmol/d

 

Female, 24 hr

14-22 mg/kg/d

0.8-1.8 g/d

8.840

8.840

124-195 mmol/kg/d

7.1-15.9 mmol/d

Cystine, qualitative

Random

Negative

---

Negative

Cystine and cysteine

24 h

10-100 mg/d

4.161 (based on cystine)

42-416 mmol/d

Dehydroepiandrosterone

 

 

 

 

 

Male, 24 hr

0.2-2 mg/d

3.467

0.7-6.9 mmol/d

 

Female, 24 hr

0.2-1.8 mg/d

 

0.7-6.2 mmol/d

Diacetic acid

Random

Negative

---

Negative

Epinephrine

24 h

<20 mg/d

5.458

<109 nmol/d

Estrogens

 

 

 

 

 

Male, 24 hr

5-18 mg/d

3.468 (based on estriol)

17-62 nmol/d

Total

Female, 24 hr

 

 

 

 

Ovulation

28-100 mg/d

0.003468

97-347 nmol/d

 

Luteal peak

22-80 mg/d

3.468

76-364 nmol/d

 

At menses

4-25 mg/d

3.699

14-87 nmol/d

 

Pregnancy

up to 45,000 mg/d

3.671

up to 156 mmol/d

 

Postmenopausal

up to 10 mg/d

3.468

up to 35 nmol/d

Fractioned

24 h, nonpregnant, midcycle

 

 

 

Estrone(E1)

__

2-25 mg/d

 

7-93 nmol/d

Estradiol (E2)

__

<10 mg/d

 

<37 nmol/d

Estriol(E3)

__

2-30 mg/d

 

7-104 nmol/d

Fat, qualitative

Random

Negative

__

Negative

FIGLU (N-formiminoglutamic acid)

 

 

 

 

 

24 h

<3 mg/d

5.740

<17.2 mmol/d

 

after 15g of L-histidine

4 mg/d

 

23.0 mmol/d

Floride

24 h

<1 mg/d

52.63

<53 mmol/d

Follicle-simulating hormone (FSH)

24 h

 

 

 

 

Adult

4-25 U/L

1

4-25 IU/L

 

Prepubertal

4-30 U/L

1

4-30 IU/L

 

Postmenopausal

40-50 U/L

1

40-50 IU/L

 

Midcycle

2 x baseline

1

2 x baseline

Fructose

24 h

30-65 mg/d

0.005551

0.17-0.36 mmol/d

Glucose

 

 

 

 

Qualitative

Random

Negative

__

Negative

Quantitative

24 h

 

 

 

Copper-reducing

Substances

 

0.5-1.5 g/d

1

0.5-1.5 g/d

Total sugars

 

average 250 mg/d

1

average 250 mg/d

Glucose

 

average 130 mg/d

0.005551

average 0.72 mmol/d

Gonadotropins, pituary (FSH and LH)

24 h

10-50 U/L

1

10-50 IU/d

Etiocholanolone

 

 

 

 

 

Male, 24 hr

1.4-5.0 mg/d

3.443

4.8-17.2 mmol/d

 

Female, 24 hr

0.8-4.0 mg/d

 

2.8-13.8 mmol/d

11-Hydroxyandrosterone

 

 

 

 

 

Male, 24 hr

0.1-0.8 mg/d

3.263

0.3-2.6 mmol/d

 

Female, 24 hr

<0.5 mg/d

 

<1.6 mmol/d

11-Hydroxyetiocholanolone

 

 

 

 

 

Male, 24 hr

0.2-0.6 mg/d

3.26

0.7-2.0 mmol/d

 

Female, 24 hr

0.1-1.1 mg/d

 

0.3-3.63 mmol/d

11-Ketoandrosterone

 

 

 

 

 

Male, 24 hr

0.2-1.0 mg/d

3.274

0.7-3.3 mmol/d

 

Female, 24 hr

0.2-0.8 mg/d

 

0.7-2.6 mmol/d

11-Ketoetiocholanolone

 

 

 

 

 

Male, 24 hr

0.2-1.0 mg/d

3.274

0.7-3.3 mmol/d

 

Female, 24 hr

0.2-0.8 mg/d

 

0.7-2.6 mmol/d

Lactose

24 h

14-40 mg/d

2.291

41-117 mmol/d

Lead

24 h

<100 mg/d

0.004826

<0.48 mmol/d

Magnesium

24 h

6.0-8.5 mEq/d

0.5000

3.0-4.3 mmol/d

Melanin, qualitative

Random

Negative

__

Negative

Mucin

24 h

100-150 mg/d

1

100-150 mg/d

Muramidase (lysozyme)

24 h

1.3-36 mg/d

1

1.3-36 mg/d

Myoglobin

 

 

 

 

Qualitative

Random

Negative

__

Negative

Quantitative

24 h

<4 mg/L

1

<4 mg/L

Osmolality

Random

500-800 mOsm/kg water

1

500-800 mmol/kg

Pentoses

24 h

2-5 mg/kg/d

1

2-5 mg/kg/d

pH

Random

4.6-8.0

1

4.6-8.0

Phenossulfonphthalein (PSP)

Urine timed after 6 mg PSP IV

 

 

 

 

15 min

20-50% dye excreted

0.01

Fraction dye excreted: 0.20-0.50

 

30 min

16-24% dye excreted

 

0.16-0.24

 

60 min

9-17% dye excreted

 

0.09-0.17

 

120 min

3-10% dye excreted

 

0.03-0.10

Phenylpyruvic acid, qualitative

Random

Negative

__

Negative

Phosphorus

Random

0.9-1.3 g/d

32.29

29-42 mmol/d

Porphobilinogen

 

 

 

 

Qualitative

Random

Negative

__

Negative

Quantitative

24 h

<1.0 mg/d

4.420

4.4 mmol/d

Potassium

24 h

40-80 mEq/d

1

40-80 mmol/d

Pregnancy tests

Concentrated morning specimen

Positive in normal pregnancies or with tumors producing chorionic gonadotropin

__

Positive in normal pregnancies or with tumors producing chorionic gonadotropin

Pregnanediol

24 h

 

 

 

 

Male

<1.5 mg/d

3.120

<4.7 mmol/d

 

Female

1-8 mg/d

3.120

3-25 mmol/d

 

Peak

1 week after ovulation

__

1 week after ovulation

 

Pregnancy

 <50 mg/d

 

 

 

Children

Negative

 

<156 mmol/d

Negative

Pregnanetriol

24 h

 

 

 

 

Male

0.4-2.4 mg/d

2.972

1.2-7.1 mmol/d

 

Female

0.5-2.0 mg/d

 

1.5-5.9 mmol/d

Children

up to 1 mg/d

up to 3 mmol/d

Protein, qualitative

Random

Negative

__

Negative

 

24 h

40-150 mg/d

1

40-150 mg/d

Reducing substances, total

24 h

0.5-1.5 mg/d

1

0.5-1.5 mg/d

Sodium

24 h

75-200 mEq/d

1

75-200 mmol/d

Solids, total

24 h

55-70 g/d

Decreases with age to 30 g/d

__

50-70 g/d

Decreases with age to 30 g/d

Specific gravity

Random

1.016-1.022(normal fluid intake)

1.001-1.035 (range)

1

Relative density (U 20°C/water 20°C)

1.016-1.022(normal fluid intake)

1.001-1.035 (range)

 

 

Sugars (excluding glucose)

Random

Negative

__

Negative

Titratable acidity

24 h

20-50 mEq/d

1

20-50 mmol/d

Urea nitrogen

24 h

6-17 g/d

35.70

214-607 mmol/d

Uric acid

24 h

250-750 mg/d

0.005948

1.5-4.5 mmol/d

Urobilinogen

       
 

2 h

0.3-1.0 Ehrlich units

1

0.3-1.0 U

 

24 h

0.05-2.5 mg/d or 0.5-4.0 Erhlich units/d

1.693

1

0.1-4.2 mmol/d

0.5-4.0 U/d

Uropepsin

       
 

Random

15-45 units/h (Anson)

7.37

111-332 U/h

 

 

24 h

 

1500-5000 units/d (Anson)

 

 

11-37 kU/h

Uroporphyrins

 

 

 

 

Qualitative

Random

Negative

__

Negative

Quantitative

25 h

10-30 mg/d

1.204

12-36 nmol/d

Vanillylmandelic acid (VMA)

24 h

1.5-7.5 mg/d

5.046

7.6-37.9 mmol/d

Volume, total

24 h

600-1600 mL/d

0.001

0.6-1.6 L/d

Zinc

24 h

0.15-1.2 mg/d

15.30

2.3-18.4 mmol/d