[Frontiers in Bioscience, 3 d152-168, February 1, 1998]

	[Frontiers in Bioscience, 3 d152-168, February 1, 1998] Reprints PubMed CAVEAT LECTOR
	REGULATION OF TRANSCRIPTION FACTOR NF KAPPA B IN IMMUNE SENESCENCE Usha Ponnappan Department of Geriatrics, Medicine, Microbiology and Immunology, University of Arkansas for Medical Sciences, and GRECC, John L. McClellan Memorial VA hospital, VA Medical Research, GC143, 151/LR, 4300 West 7^th street, Little Rock, Arkansas 72205 Received 1/15/97 Accepted 1/29/98 TABLE OF CONTENTS 1. Abstract 2 Introduction: Aging and Immune function 2.1. T Lymphocyte function in Immune senescence 3 Transcription factor NF kappa B 3.1. Inhibitor of Kappa B: I kappa B 4.Signals and signaling pathways for NF kappa B 4.1.Modification and degradation of I kappa B 4.2. Autoregulation of NF kappa B and I kappa B 4.3.Role of NF kappa B in immune response 5. NF kappa B and immune senescence 6. Conclusions and Perspectives 7. Acknowledgment 8. References 9. Entire manuscript Key words: Immunology, Immune function, Aging, Immune senesence, NF kappa B, I kappa B, Proteasome, Ubiquitin mediated degradation, T lymphocytes, TNF-alpha, Phosphorylation, Immune response, Cytokines, Signal transduction, rel family, c-rel, RelB, p50, p65, Memory and naive T cell subsets, IL-2, IL-2 receptor-alpha, Autoimmunity, Immune dysregulation Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience, 3 d152-168, February 1, 1998]
Reprints
PubMed
CAVEAT LECTOR

REGULATION OF TRANSCRIPTION FACTOR NF KAPPA B IN IMMUNE SENESCENCE

Usha Ponnappan

Department of Geriatrics, Medicine, Microbiology and Immunology, University of Arkansas for Medical Sciences, and GRECC, John L. McClellan Memorial VA hospital, VA Medical Research, GC143, 151/LR, 4300 West 7^th street, Little Rock, Arkansas 72205

Received 1/15/97 Accepted 1/29/98

TABLE OF CONTENTS

1. Abstract
2 Introduction: Aging and Immune function: 2.1. T Lymphocyte function in Immune senescence
3 Transcription factor NF kappa B: 3.1. Inhibitor of Kappa B: I kappa B
4.Signals and signaling pathways for NF kappa B: 4.1.Modification and degradation of I kappa B
4.2. Autoregulation of NF kappa B and I kappa B
4.3.Role of NF kappa B in immune response
5. NF kappa B and immune senescence
6. Conclusions and Perspectives
7. Acknowledgment
8. References
9. Entire manuscript

Key words: Immunology, Immune function, Aging, Immune senesence, NF kappa B, I kappa B, Proteasome, Ubiquitin mediated degradation, T lymphocytes, TNF-alpha, Phosphorylation, Immune response, Cytokines, Signal transduction, rel family, c-rel, RelB, p50, p65, Memory and naive T cell subsets, IL-2, IL-2 receptor-alpha, Autoimmunity, Immune dysregulation

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.