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INTEGRINS DURING MUSCLE DEVELOPMENT AND IN MUSCULAR DYSTROPHIES
Donald Gullberg, Teet Velling, Lars Lohikangas, Carl-Fredrik Tiger
Department of Animal Physiology, Uppsala University, BMC, Box 596, S-751 24 Uppsala , Sweden
Received 9/7/98 Accepted 9/21/98
TABLE OF CONTENTS
- 1. Abstract
- 2. In vivo myogenesis
- 2.1. Early vertebrate myogenesis
2.2. Lessons from Drosophila myogenesis
- 3. In vitro myogenesis
- 4. Integrins during Muscle Development
- 4.1. Integrins as cell-cell receptors
4.2. Integrins as migration receptors
4.3. Integrins as signaling receptors
4.4. Integrins as mechanical links
- 5. Integrins in Muscular Dystrophy
- 5.1. Muscle regeneration
5.2. Fibrosis
5.3. Integrins as cell-cell receptors
5.4. Integrins as migration receptors
5.5. Integrins as signaling receptors
5.6. Integrins as mechanical links
- 6. Perspective
- 7. References
- 8. Entire manuscript
Key words: Somite, Drosophila, Muscle Development, Muscular dystrophy, Integrin, Extracellular Matrix
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