[Frontiers in Bioscience 3, d176-193, February 15, 1998]

	[Frontiers in Bioscience 3, d176-193, February 15, 1998] Reprints PubMed CAVEAT LECTOR
	REGULATION OF BILE ACID SYNTHESIS John Y. L. Chiang Department of Biochemistry and Molecular Pathology, Northeastern Ohio Universities College of Medicine, P. O. Box 95, Rootstown, OH 44272 Received 1/22/98 Accepted 2/2/98 TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Bile Acid Biosynthesis Pathways 3.1. Classic Pathway 3.2. Alternative pathway 4. Major enzymes in Bile Acid Synthesis 4.1. Cholesterol 7alpha-hydroxylase 4.1.1. Bile acid feedback 4.1.2. Role of cholesterol 4.1.3. Hormonal regulation 4.1.4. Diurnal rhythm 4.1.5. Other factors 4.1.6. Regulation of the CYP7A gene expression 4.1.7. Molecular Mechanisms of regulation 4.2. Sterol 27-hydroxylase 4.3. Oxysterol 7alpha-hydroxylase 4.4. Sterol 12alpha-hydroxylase 5. Conclusion and Future Perspective 6. Acknowledgment 7. References 9. Entire manuscript Key words: Bile acid synthesis, Cytochrome P450, cholesterol 7alpha-hydroxylase, Sterol 27-hydroxylase, Sterol 12alpha-hydroxylase, Oxysterol 7alpha-hydroxylase, Gene regulation, Gene transcription Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 3, d176-193, February 15, 1998]
Reprints
PubMed
CAVEAT LECTOR

REGULATION OF BILE ACID SYNTHESIS

John Y. L. Chiang

Department of Biochemistry and Molecular Pathology, Northeastern Ohio Universities College of Medicine, P. O. Box 95, Rootstown, OH 44272

Received 1/22/98 Accepted 2/2/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Bile Acid Biosynthesis Pathways: 3.1. Classic Pathway
3.2. Alternative pathway
4. Major enzymes in Bile Acid Synthesis: 4.1. Cholesterol 7alpha-hydroxylase
4.1.1. Bile acid feedback
4.1.2. Role of cholesterol
4.1.3. Hormonal regulation
4.1.4. Diurnal rhythm
4.1.5. Other factors
4.1.6. Regulation of the CYP7A gene expression
4.1.7. Molecular Mechanisms of regulation
4.2. Sterol 27-hydroxylase
4.3. Oxysterol 7alpha-hydroxylase
4.4. Sterol 12alpha-hydroxylase
5. Conclusion and Future Perspective
6. Acknowledgment
7. References
9. Entire manuscript

Key words: Bile acid synthesis, Cytochrome P450, cholesterol 7alpha-hydroxylase, Sterol 27-hydroxylase, Sterol 12alpha-hydroxylase, Oxysterol 7alpha-hydroxylase, Gene regulation, Gene transcription

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.