[Frontiers in Bioscience 2, a37-45, November 1, 1997]

	[Frontiers in Bioscience 2, a37-45, November 1, 1997] Reprints PubMed CAVEAT LECTOR
	A p53 GROWTH ARREST PROTECTS FIBROBLASTS FROM ANTICANCER AGENTS E. Siobhan McCormack, Arthur M. Bruskin, Gary V. Borzillo OSI Pharmaceuticals Inc., 106 Charles Lindbergh Blvd., Uniondale, NY 11553-3649 Received 10/27/97 Accepted October 31, 1997 TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Materials and Methods 3.1 Cell lines 3.2 Protein analyses 3.3 Chemoprotection colony assays 4. Results 4.1 Protection from taxol 4.2 Protection from vinblastine, etoposide and Ara-C 4.3 p53 enhances survival weakly for cells treated with 5-FU, and does not protect from cisplatin 5. Discussion 6. Acknowledgment 7. References 8. Entire manuscript Key words: p53, Chemoprotection, Cell cycle, G1 phase, Chemotherapy Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 2, a37-45, November 1, 1997]
Reprints
PubMed
CAVEAT LECTOR

A p53 GROWTH ARREST PROTECTS FIBROBLASTS FROM ANTICANCER AGENTS

E. Siobhan McCormack, Arthur M. Bruskin, Gary V. Borzillo

OSI Pharmaceuticals Inc., 106 Charles Lindbergh Blvd., Uniondale, NY 11553-3649

Received 10/27/97 Accepted October 31, 1997

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Materials and Methods: 3.1 Cell lines 3.2 Protein analyses 3.3 Chemoprotection colony assays
4. Results: 4.1 Protection from taxol 4.2 Protection from vinblastine, etoposide and Ara-C 4.3 p53 enhances survival weakly for cells treated with 5-FU, and does not protect from cisplatin
5. Discussion
6. Acknowledgment
7. References
8. Entire manuscript

Key words: p53, Chemoprotection, Cell cycle, G1 phase, Chemotherapy

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.