[Frontiers in Bioscience 1, d48-58, March 1, 1996]
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CAVEAT LECTOR



DnaA- and PriA-DEPENDENT PRIMOSOMES: TWO DISTINCT REPLICATION COMPLEXES FOR REPLICATION OF Escherichia coli CHROMOSOME

Hisao Masai and Ken-ichi Arai.

Department of Molecular and Developmental Biology, Institute of Medical Science, University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo, 108, Japan

Received 01/17/96; Accepted 02/17/96; On-line 03/01/96

1. Summary
2. Introduction
3. phiX174-type (PriA-dependent) primosome
3.1 Primosomal proteins for assembly of the phiX174-type primosome
3.2 n'-pas isolated from various plasmids
4. DnaA-dependent primosome
4.1 oriC primosome
4.2 ABC primosome
4.3 ABC primosome can support progression of replication forks
5. DnaA/oriC-independent replication of the E. coli chromosome
6. Genetic study of primosomal proteins required for PriA-dependent primosome
6.1 dnaT (protein i)
6.2 PriA (protein n')
7. Two primosomes for replication of the E. coli chromosome and various plasmid replicons
8. PriA-dependent primosome for replication under hard life
9. Future perspectives
10. Acknowledgments
11. References
12. Entire manuscript